Page last updated: 2024-10-31

midazolam and Ventricular Fibrillation

midazolam has been researched along with Ventricular Fibrillation in 6 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"Pericardial lidocaine (1) decreased heart rate without affecting stroke volume, (2) preserved the tachycardiac response to isoproterenol but completely blocked the response to atropine, and (3) increased the voltage thresholds for arrhythmias and ventricular fibrillation induced by an electrical fibrillator."3.74Effects of pericardial lidocaine on hemodynamic parameters and responses in dogs anesthetized with midazolam and fentanyl. ( Akamatsu, S; Dohi, S; Suzuki, A; Takada, M, 2007)
"Midazolam was administered during the procedure by staff who were blinded to the state/trait anxiety scores and the type of consent the patient had received."2.68Effect of informed consent on anxiety in patients undergoing diagnostic electrophysiology studies. ( Goldberger, JJ; Kadish, AH; Kruse, J; Parker, MA, 1997)
"Slow ventricular tachycardia (VT) in patients with devices such as an implantable cardioverter - defibrillator (ICD) is more common than in the rest of the population."1.46Slow ventricular tachycardia in a 91-year-old man with implantable cardioverter-defibrillator and acute respiratory failure. ( Candelmo, F; Carifi, G; Di Grezia, F; Landi, CAE; Landi, E; Salsano, E; Tibullo, L; Vargas, N, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vargas, N1
Tibullo, L1
Landi, CAE1
Carifi, G1
Landi, E1
Salsano, E1
Di Grezia, F1
Candelmo, F1
Compton, R1
Spiller, HA1
Bosse, GM1
Takada, M1
Dohi, S1
Akamatsu, S1
Suzuki, A1
Goldberger, JJ1
Kruse, J1
Parker, MA1
Kadish, AH1
Vrána, M2
Fejfar, Z2
Hess, L2
Blazek, Z1
Vránová, Z1

Trials

1 trial available for midazolam and Ventricular Fibrillation

ArticleYear
Effect of informed consent on anxiety in patients undergoing diagnostic electrophysiology studies.
    American heart journal, 1997, Volume: 134, Issue:1

    Topics: Anti-Anxiety Agents; Anxiety; Arrhythmias, Cardiac; Bradycardia; Cardiac Catheterization; Cardiac Ou

1997

Other Studies

5 other studies available for midazolam and Ventricular Fibrillation

ArticleYear
Slow ventricular tachycardia in a 91-year-old man with implantable cardioverter-defibrillator and acute respiratory failure.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:8

    Topics: Aged, 80 and over; Continuous Positive Airway Pressure; Defibrillators, Implantable; Humans; Hypnoti

2017
Fatal fluoxetine ingestion with postmortem blood concentrations.
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bradycardia; Child, Preschool; Dia

2005
Effects of pericardial lidocaine on hemodynamic parameters and responses in dogs anesthetized with midazolam and fentanyl.
    Journal of cardiothoracic and vascular anesthesia, 2007, Volume: 21, Issue:3

    Topics: Anesthesia; Animals; Coronary Artery Bypass, Off-Pump; Dogs; Fentanyl; Heart Rate; Lidocaine; Midazo

2007
Analgosedation-enhanced baroreflex sensitivity in acute local myocardial ischaemia.
    Cor et vasa, 1991, Volume: 33, Issue:5

    Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Electrocardiography; Fentanyl; Midazolam; Pressorec

1991
The electrostabilizing effect of a combination of midazolam and fentanyl: an experimental study in the dog.
    Cor et vasa, 1989, Volume: 31, Issue:5

    Topics: Animals; Blood Pressure; Dogs; Drug Combinations; Electrocardiography; Fentanyl; Heart Conduction Sy

1989