midazolam has been researched along with Uremia in 1 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of renal failure upon the "in vitro" binding of midazolam, a new water-soluble short-acting benzodiazepine, has been studied in man." | 1.28 | The influence of renal failure on the kinetics of intravenous midazolam: an "in vitro" and "in vivo" study. ( Calvo, R; Martínez, I; Rodríguez-Sasiain, JM; Suárez, E, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calvo, R | 1 |
| Suárez, E | 1 |
| Rodríguez-Sasiain, JM | 1 |
| Martínez, I | 1 |
1 other study available for midazolam and Uremia
| Article | Year |
|---|---|
The influence of renal failure on the kinetics of intravenous midazolam: an "in vitro" and "in vivo" study.
Topics: Adolescent; Adult; Animals; Blood Proteins; Brain; Disease Models, Animal; Female; Humans; Injection | 1992 |