midazolam has been researched along with Strabismus in 14 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Strabismus: Misalignment of the visual axes of the eyes. In comitant strabismus the degree of ocular misalignment does not vary with the direction of gaze. In noncomitant strabismus the degree of misalignment varies depending on direction of gaze or which eye is fixating on the target. (Miller, Walsh & Hoyt's Clinical Neuro-Ophthalmology, 4th ed, p641)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In paediatric patients undergoing strabismus surgery intranasal dexmedetomidine 2 μg kg premedication decreases the incidence of emergence delirium and PONV, and improves parents' satisfaction compared with oral midazolam." | 9.34 | Intranasal dexmedetomidine versus oral midazolam premedication to prevent emergence delirium in children undergoing strabismus surgery: A randomised controlled trial. ( Chen, W; Lin, J; Lin, Y; Sun, Y; Yao, Y; Zheng, X, 2020) |
| "03 mg/kg of midazolam just before the end of surgery reduces emergence agitation without delaying the emergence time in children having strabismus surgery with sevoflurane anesthesia." | 9.19 | Comparison of the effects of 0.03 and 0.05 mg/kg midazolam with placebo on prevention of emergence agitation in children having strabismus surgery. ( Cho, EJ; Cho, JE; Lee, HW; Yoon, SZ, 2014) |
| "Prophylactic administration of either of either granisetron, ondansetron, midazolam combined with dexamethasone markedly decreases the incidence of PONV following strabismus surgery in pediatrics." | 9.14 | Combination therapy in the prevention of PONV after strabismus surgery in children: granisetron, ondansetron, midazolam with dexamethasone. ( Marouf, H; Riad, W, 2009) |
| "One hundred and twenty children, 1-9 years old, undergoing elective strabismus surgery, were randomly assigned to receive sevoflurane or remifentanil." | 9.13 | Effect of remifentanil on oculocardiac reflex in paediatric strabismus surgery. ( Choi, SR; Chung, CJ; Lee, JH; Lee, JM; Lee, SC, 2008) |
| "Prophylactic midazolam with or without dexamethasone reduces the incidence of PONV in children undergoing strabismus repair." | 9.12 | Effect of midazolam, dexamethasone and their combination on the prevention of nausea and vomiting following strabismus repair in children. ( Abdulla, A; Altaf, R; Oudan, H; Riad, W, 2007) |
| "This is a prospective randomized double-blind trial conducted to determine whether preoperative orally administered clonidine causes or potentiates postoperative vomiting in 140 children (3-12 yr) undergoing strabismus surgery." | 9.08 | Oral clonidine premedication reduces vomiting in children after strabismus surgery. ( Asano, M; Maekawa, N; Mikawa, K; Nishina, K; Obara, H, 1995) |
| " Comaintenance of anesthesia was accomplished using a stepped-down infusion of propofol with midazolam." | 7.71 | The immediate postoperative adjustment of sutures in strabismus surgery with comaintenance of anesthesia using propofol and midazolam. ( Cogen, MS; Guthrie, ME; Vinik, HR, 2002) |
| "In paediatric patients undergoing strabismus surgery intranasal dexmedetomidine 2 μg kg premedication decreases the incidence of emergence delirium and PONV, and improves parents' satisfaction compared with oral midazolam." | 5.34 | Intranasal dexmedetomidine versus oral midazolam premedication to prevent emergence delirium in children undergoing strabismus surgery: A randomised controlled trial. ( Chen, W; Lin, J; Lin, Y; Sun, Y; Yao, Y; Zheng, X, 2020) |
| "03 mg/kg of midazolam just before the end of surgery reduces emergence agitation without delaying the emergence time in children having strabismus surgery with sevoflurane anesthesia." | 5.19 | Comparison of the effects of 0.03 and 0.05 mg/kg midazolam with placebo on prevention of emergence agitation in children having strabismus surgery. ( Cho, EJ; Cho, JE; Lee, HW; Yoon, SZ, 2014) |
| "In total, 405 paediatric patients (aged 4-12 years) undergoing strabismus surgery were enrolled and randomly assigned to one of two groups, ramosetron or ramosetron with midazolam." | 5.16 | Comparison of the antiemetic effect of ramosetron and combined ramosetron and midazolam in children: a double-blind, randomised clinical trial. ( Byon, HJ; Kim, HS; Kim, JT; Lee, SJ, 2012) |
| "Propofol or remifentanil anesthesia was associated with a higher incidence of OCR during pediatric strabismus surgery than sevoflurane and desflurane anesthesia, when either ketamine or midazolam was used as an induction agent." | 5.14 | Effect of different anesthetic agents on oculocardiac reflex in pediatric strabismus surgery. ( Choi, SR; Chung, CJ; Lee, JH; Lee, SC; Park, SW, 2009) |
| "Prophylactic administration of either of either granisetron, ondansetron, midazolam combined with dexamethasone markedly decreases the incidence of PONV following strabismus surgery in pediatrics." | 5.14 | Combination therapy in the prevention of PONV after strabismus surgery in children: granisetron, ondansetron, midazolam with dexamethasone. ( Marouf, H; Riad, W, 2009) |
| "One hundred and twenty children, 1-9 years old, undergoing elective strabismus surgery, were randomly assigned to receive sevoflurane or remifentanil." | 5.13 | Effect of remifentanil on oculocardiac reflex in paediatric strabismus surgery. ( Choi, SR; Chung, CJ; Lee, JH; Lee, JM; Lee, SC, 2008) |
| "Prophylactic midazolam with or without dexamethasone reduces the incidence of PONV in children undergoing strabismus repair." | 5.12 | Effect of midazolam, dexamethasone and their combination on the prevention of nausea and vomiting following strabismus repair in children. ( Abdulla, A; Altaf, R; Oudan, H; Riad, W, 2007) |
| "This is a prospective randomized double-blind trial conducted to determine whether preoperative orally administered clonidine causes or potentiates postoperative vomiting in 140 children (3-12 yr) undergoing strabismus surgery." | 5.08 | Oral clonidine premedication reduces vomiting in children after strabismus surgery. ( Asano, M; Maekawa, N; Mikawa, K; Nishina, K; Obara, H, 1995) |
| "Droperidol can reduce the high incidence of vomiting after pediatric strabismus surgery; however, its use may be associated with sedation, delayed hospital discharge, dysphoria and extrapyramidal signs." | 5.07 | Antiemetic prophylaxis for strabismus surgery. ( Bonn, G; Clarke, W; Noël, LP; Rhine, E; Roberts, D; Splinter, W, 1994) |
| " Our anesthetic protocol for strabismus surgery included postoperative nausea and vomiting prevention using dexamethasone and ondansetron." | 3.91 | Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery. ( Couret, C; Ducloyer, JB; Le Meur, G; Lebranchu, P; Lejus-Bourdeau, C; Magne, C; Weber, M, 2019) |
| "8 years) who were treated with SSASS using intravenous midazolam, fentanyl, and topical anesthesia." | 3.72 | Single-stage adjustable strabismus surgery for restrictive strabismus. ( Reinecke, RD; Sharma, P, 2003) |
| " Comaintenance of anesthesia was accomplished using a stepped-down infusion of propofol with midazolam." | 3.71 | The immediate postoperative adjustment of sutures in strabismus surgery with comaintenance of anesthesia using propofol and midazolam. ( Cogen, MS; Guthrie, ME; Vinik, HR, 2002) |
| "Midazolam and propofol have been examined with the aim of reducing emergence agitation after sevoflurane anaesthesia." | 2.76 | Prophylactic use of midazolam or propofol at the end of surgery may reduce the incidence of emergence agitation after sevoflurane anaesthesia. ( Kim, YH; Lim, HJ; Yoon, SM; Yoon, SZ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Yao, Y | 1 |
| Sun, Y | 1 |
| Lin, J | 1 |
| Chen, W | 1 |
| Lin, Y | 1 |
| Zheng, X | 1 |
| Ducloyer, JB | 1 |
| Couret, C | 1 |
| Magne, C | 1 |
| Lejus-Bourdeau, C | 1 |
| Weber, M | 1 |
| Le Meur, G | 1 |
| Lebranchu, P | 1 |
| Cho, EJ | 1 |
| Yoon, SZ | 2 |
| Cho, JE | 1 |
| Lee, HW | 1 |
| Chung, CJ | 2 |
| Lee, JM | 1 |
| Choi, SR | 2 |
| Lee, SC | 2 |
| Lee, JH | 2 |
| Park, SW | 1 |
| Riad, W | 2 |
| Marouf, H | 1 |
| Kim, YH | 1 |
| Lim, HJ | 1 |
| Yoon, SM | 1 |
| Byon, HJ | 1 |
| Lee, SJ | 1 |
| Kim, JT | 1 |
| Kim, HS | 1 |
| Cogen, MS | 1 |
| Guthrie, ME | 1 |
| Vinik, HR | 1 |
| Dal, D | 1 |
| Celiker, V | 1 |
| Sharma, P | 1 |
| Reinecke, RD | 1 |
| Altaf, R | 1 |
| Abdulla, A | 1 |
| Oudan, H | 1 |
| Splinter, W | 1 |
| Noël, LP | 1 |
| Roberts, D | 1 |
| Rhine, E | 1 |
| Bonn, G | 1 |
| Clarke, W | 1 |
| Mikawa, K | 1 |
| Nishina, K | 1 |
| Maekawa, N | 1 |
| Asano, M | 1 |
| Obara, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dexmedetomidine Versus Midazolam Premedication on Emergence Agitation After Strabismus Surgery in Children[NCT01895023] | Phase 4 | 156 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| Midazolam Effect on Agitation Postnasal Surgery: A Double Blinded Randomized Controlled Trial[NCT05165914] | 100 participants (Actual) | Interventional | 2021-05-27 | Completed | |||
| Late Onset Postoperative Nausea and Vomiting Following Strabismus Surgery in Pediatric.What Combination is Better[NCT00918190] | 75 participants (Anticipated) | Interventional | 2009-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 trials available for midazolam and Strabismus
| Article | Year |
|---|---|
Intranasal dexmedetomidine versus oral midazolam premedication to prevent emergence delirium in children undergoing strabismus surgery: A randomised controlled trial.
Topics: Child; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Hypnotics and Sedatives; Mi | 2020 |
Comparison of the effects of 0.03 and 0.05 mg/kg midazolam with placebo on prevention of emergence agitation in children having strabismus surgery.
Topics: Adolescent; Akathisia, Drug-Induced; Anesthesia Recovery Period; Child; Child, Preschool; Double-Bli | 2014 |
Effect of remifentanil on oculocardiac reflex in paediatric strabismus surgery.
Topics: Anesthesia; Blood Pressure; Child; Child, Preschool; Female; Heart Rate; Humans; Infant; Male; Midaz | 2008 |
Effect of different anesthetic agents on oculocardiac reflex in pediatric strabismus surgery.
Topics: Androstanols; Anesthesia; Anesthesia, General; Anesthetics; Anesthetics, Dissociative; Anesthetics, | 2009 |
Combination therapy in the prevention of PONV after strabismus surgery in children: granisetron, ondansetron, midazolam with dexamethasone.
Topics: Antiemetics; Child; Child, Preschool; Dexamethasone; Drug Therapy, Combination; Female; Granisetron; | 2009 |
Prophylactic use of midazolam or propofol at the end of surgery may reduce the incidence of emergence agitation after sevoflurane anaesthesia.
Topics: Adolescent; Akathisia, Drug-Induced; Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation | 2011 |
Comparison of the antiemetic effect of ramosetron and combined ramosetron and midazolam in children: a double-blind, randomised clinical trial.
Topics: Antiemetics; Benzimidazoles; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination | 2012 |
Effect of midazolam, dexamethasone and their combination on the prevention of nausea and vomiting following strabismus repair in children.
Topics: Adjuvants, Anesthesia; Antiemetics; Child; Child, Preschool; Dexamethasone; Double-Blind Method; Dru | 2007 |
Antiemetic prophylaxis for strabismus surgery.
Topics: Adolescent; Child; Child, Preschool; Droperidol; Humans; Incidence; Infant; Midazolam; Oculomotor Mu | 1994 |
Oral clonidine premedication reduces vomiting in children after strabismus surgery.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthesia, Inhalation; Anti-Inflammatory Agents, N | 1995 |
4 other studies available for midazolam and Strabismus
| Article | Year |
|---|---|
Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery.
Topics: Acetaminophen; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anti-Anxiety Agen | 2019 |
The immediate postoperative adjustment of sutures in strabismus surgery with comaintenance of anesthesia using propofol and midazolam.
Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Combined; Anesthetics, Intravenous; Female; Humans | 2002 |
Anaesthetic management of a strabismus patient with phenylketonuria.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Humans; Intubation, I | 2003 |
Single-stage adjustable strabismus surgery for restrictive strabismus.
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia; Anesthetics, Dissociative; Anesthetics, Intravenous; An | 2003 |