midazolam has been researched along with Respiratory Insufficiency in 77 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
Excerpt | Relevance | Reference |
---|---|---|
"Continuous midazolam infusion is commonly used for the management of status epilepticus (SE)." | 9.11 | Efficacy of continuous midazolam infusion and mortality in childhood refractory generalized convulsive status epilepticus. ( Aydin, A; Gulez, P; Kavakli, T; Ozdemir, D; Uran, N; Yendur, G, 2005) |
"To discuss mainly the use of propofol and barbiturates in the anesthesia of refractory status epilepticus (RSE)." | 8.84 | Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and cons. ( Kälviäinen, R; Parviainen, I; Ruokonen, E, 2007) |
"Significant respiratory depression did not occur in either group." | 6.66 | [Is there a risk of global respiratory insufficiency with the use of intramuscular midazolam as premedication for bronchoscopy?]. ( Bertolaso, E; Wild, A, 1988) |
"Low-dose etomidate combined with oxycodone and midazolam for endoscopic injection sclerotherapy could reduce the incidence of hypoxia without increasing the incidence of complications." | 5.69 | Application of low-dose etomidate combined with oxycodone and midazolam in endoscopic injection sclerotherapy. ( Cao, Y; Hao, S; Quan, Z; Yao, J; Zhou, C, 2023) |
"Propofol was commenced in all patients at a mean infusion rate of 18." | 5.38 | Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation. ( Drewitz, I; Heitmann, K; Hoffmann, BA; Rostock, T; Salukhe, TV; Steven, D; Willems, S, 2012) |
"Because of the prevalence of substance abuse, cocaine use should be considered in the differential diagnosis of sudden cardiovascular compromise in parturients." | 5.28 | Anaesthetic management of a parturient with myocardial infarction related to cocaine use. ( Chen, K; Forrester, RM; Glassenberg, R; Liu, SS; Murphy, GS, 1992) |
"To determine whether supplemental oxygen reduces the incidence of hypoxia by 20% in study patients receiving midazolam and fentanyl for emergency department procedural sedation and analgesia." | 5.12 | The utility of supplemental oxygen during emergency department procedural sedation and analgesia with midazolam and fentanyl: a randomized, controlled trial. ( Chudnofsky, CR; Deitch, K; Dominici, P, 2007) |
"Continuous midazolam infusion is commonly used for the management of status epilepticus (SE)." | 5.11 | Efficacy of continuous midazolam infusion and mortality in childhood refractory generalized convulsive status epilepticus. ( Aydin, A; Gulez, P; Kavakli, T; Ozdemir, D; Uran, N; Yendur, G, 2005) |
"To discuss mainly the use of propofol and barbiturates in the anesthesia of refractory status epilepticus (RSE)." | 4.84 | Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and cons. ( Kälviäinen, R; Parviainen, I; Ruokonen, E, 2007) |
"0 mg of midazolam intravenously at least 20 minutes prior to the induction of anesthesia and the effects of midazolam on the patient's respiratory function were analyzed." | 3.85 | Quantification of respiratory depression during pre-operative administration of midazolam using a non-invasive respiratory volume monitor. ( Brayanov, JB; Gonzalez Castro, LN; Mehta, JH; Mullen, GJ, 2017) |
"Significantly greater incidence of respiratory depression was reported for ketofol group (11/20; 55%) when compared to propofol group (3/20; 15%) (p = 0." | 2.78 | A double blind randomized trial of ketofol versus propofol for endodontic treatment of anxious pediatric patients. ( Gauba, K; Goyal, A; Jain, K; Kapur, A; Mittal, N, 2013) |
"Midazolam + alfentanil and propofol are equally safe for sedation during bronchoscopy." | 2.76 | Propofol safety in bronchoscopy: prospective randomized trial using transcutaneous carbon dioxide tension monitoring. ( Carmi, U; Fruchter, O; Kramer, MR; Rosengarten, D; Zemtzov, D, 2011) |
"Propofol was administered until the patients did not respond to a verbal command." | 2.74 | Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy. ( Bulut, M; Ganidagli, S; Koruk, S; Mizrak, A; Oner, U, 2009) |
"Twenty-one patients (16, 6%) had respiratory depression [hypercarbia (ETco2 > 50 mm Hg) or hypoxia (oxygen saturation > 90% for over 1 minute)], 21 patients (16, 6%) had hypercarbia, and 4 patients (3." | 2.71 | The value of capnography during sedation or sedation/analgesia in pediatric minor procedures. ( Yapcoǧlu, H; Yldzdaş, D; Ylmaz, HL, 2004) |
"Significant respiratory depression did not occur in either group." | 2.66 | [Is there a risk of global respiratory insufficiency with the use of intramuscular midazolam as premedication for bronchoscopy?]. ( Bertolaso, E; Wild, A, 1988) |
"Neither midazolam-induced laryngospasm nor its reversal with flumazenil have previously been reported." | 2.40 | Reversal of midazolam-induced laryngospasm with flumazenil. ( Davis, DP; Hamilton, RS; Webster, TH, 1998) |
"Clonidine is a sedative-sparing agent and this can help reduce complications associated with prolonged use of opioids and benzodiazepines." | 1.72 | Use of continuous infusion of clonidine for sedation in critically ill infants and children. ( Bourdon, O; Dauger, S; Deho, A; Prot-Labarthe, S; Sadozai, L, 2022) |
"Administration of chloral hydrate to hospitalized infants undergoing minor procedures is associated with a lower risk for adverse events compared to other sedatives." | 1.56 | Comparative safety profile of chloral hydrate versus other sedatives for procedural sedation in hospitalized infants. ( Balevic, S; Chu, V; Clark, R; Crenshaw, EG; Dallefeld, SH; Daniel, KR; Gilleskie, ML; Greenberg, RG; Kumar, KR; Smith, DS; Smith, PB; Zimmerman, KO, 2020) |
"Midazolam pretreatment did not affect heroin-induced brain hypoxia but potentiated the initial hypothermia induced by heroin." | 1.51 | Interactions of benzodiazepines with heroin: Respiratory depression, temperature effects, and behavior. ( Afzal, A; Kiyatkin, EA, 2019) |
" The outcome measures were amount of midazolam, adverse events associated with sedation, and hemodynamics." | 1.48 | Dexmedetomidine is safe and reduces the additional dose of midazolam for sedation during endoscopic retrograde cholangiopancreatography in very elderly patients. ( Andoh, A; Bamba, S; Fujimoto, T; Hasegawa, H; Imai, T; Inatomi, O; Nishida, A; Sugimoto, M; Takahashi, K; Yamashita, N; Yokota, Y, 2018) |
"Slow ventricular tachycardia (VT) in patients with devices such as an implantable cardioverter - defibrillator (ICD) is more common than in the rest of the population." | 1.46 | Slow ventricular tachycardia in a 91-year-old man with implantable cardioverter-defibrillator and acute respiratory failure. ( Candelmo, F; Carifi, G; Di Grezia, F; Landi, CAE; Landi, E; Salsano, E; Tibullo, L; Vargas, N, 2017) |
"5 K: the standard dosage of ketamine (0." | 1.43 | [Evaluation of Anesthesia Method to Minimize Intraoperative Body Movement and Respiratory Depression for Dilatation and Curettage A Retrospective Study]. ( Kitamura, J; Yamaguchi, S, 2016) |
"Isoflurane is a representative inhalant anesthesia used in laboratory animals." | 1.42 | Effect of midazolam and butorphanol premedication on inhalant isoflurane anesthesia in mice. ( Iimuro, M; Inomata, T; Sato, R; Tsukamoto, A; Yamazaki, J, 2015) |
"To determine the risk factors for respiratory depression during retrobulbar block administration before vitreoretinal surgery." | 1.42 | Risk factors for respiratory depression in patients undergoing retrobulbar block for vitreoretinal surgery. ( Brock-Utne, JG; Drover, DR; He, L; Leng, JC; Leng, T; Silva, RA, 2015) |
"The detection of critical respiratory depression usually occurs after the event." | 1.42 | Can short-term heart rate variability be used to monitor fentanyl-midazolam induced changes in ANS preceding respiratory depression? ( Owen, H; Reynolds, KJ; Smith, AL, 2015) |
"In patients with severe neck subcutaneous emphysema, management of difficult airway is the most important safety issue in the practice of anesthesia." | 1.40 | [Anesthetic management of a patient with severe subcutaneous and mediastinal emphysema due to pertussis infection]. ( Ideno, S; Ishikawa, S; Mikasa, H; Miyazawa, N; Shinto, A; Wakamiya, R; Yamamoto, S, 2014) |
"Propofol was commenced in all patients at a mean infusion rate of 18." | 1.38 | Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation. ( Drewitz, I; Heitmann, K; Hoffmann, BA; Rostock, T; Salukhe, TV; Steven, D; Willems, S, 2012) |
"Ziprasidone is an atypical antipsychotic approved for the treatment of schizophrenia and bipolar mania in adults and is used off label in children and adolescents." | 1.36 | Respiratory failure following isolated ziprasidone ingestion in a toddler. ( Gresham, C; Ruha, AM, 2010) |
"Transcutaneous PCO(2 )(PtcCO(2)), oxygen saturation, patients' tolerance, time after FB until recovery and application of drug dosage were assessed in patients receiving either midazolam with alfentanil (n = 15) or midazolam alone (n = 15) for sedation for FB." | 1.36 | Sedation during flexible bronchoscopy in patients with pre-existing respiratory failure: Midazolam versus Midazolam plus Alfentanil. ( Dreher, M; Ekkernkamp, E; Kabitz, HJ; Storre, JH; Windisch, W, 2010) |
"Because of the resulting respiratory depression the patient had to be intubated." | 1.35 | ["Liquid ecstasy": gamma-butyrolactone withdrawal delirium with rhabdomyolysis and dialysis dependent renal failure]. ( Busch, HJ; Schwab, T; Supady, A, 2009) |
"The case is reported of a female patient with attack-like neuropathic pain following lower arm injury with repeated respiratory depression and unconsciousness even after several administrations of sufficiently dosed analgetics for suppression of the attacks." | 1.35 | [Life-threatening respiratory depression after pain therapy]. ( Gläser, M; Kohlhaas, K; Maier, C; Tegenthoff, M, 2008) |
"Conditions precipitating acute respiratory failure (ARF) were classified into two groups: type 1 (38 episodes) and type 2 (78 episodes)." | 1.35 | Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study. ( Concha, A; Díaz, JJ; Los Arcos, M; Mayordomo-Colunga, J; Medina, A; Menéndez, S; Rey, C, 2009) |
"Although the incidence of respiratory depression was higher in patients receiving deep sedation with propofol than in patients who were lightly sedated (17." | 1.32 | Use of deep intravenous sedation with propofol and the laryngeal mask airway during transesophageal echocardiography. ( Arens, J; Ferson, D; Sapire, K; Sinha, A; Swafford, J; Thakar, D, 2003) |
" Dosing of the analgesics and sedatives was based on a neonatal sedation score for ventilated infants." | 1.32 | Endogenous distress in ventilated full-term newborns with acute respiratory failure. ( Aretz, S; Licht, C; Roth, B, 2004) |
"Assessment of respiratory depression caused by long-term sedation with sufentanil, midazolam and clonidine." | 1.31 | Respiratory depression under long-term sedation with sufentanil, midazolam and clonidine has no clinical significance. ( Bause, H; Prause, A; Scholz, J; Schulte am Esch, J; Wappler, F, 2000) |
"There was no previous history of seizures." | 1.31 | Bilateral frontal haemorrhages associated with continuous spinal analgesia. ( Buist, M; Burnes, J; Crofts, TR; Monagle, J, 2001) |
"Flumazenil was administered by a randomly selected route [0." | 1.30 | Comparison of routes of flumazenil administration to reverse midazolam-induced respiratory depression in a canine model. ( Cordell, WH; Heniff, MS; Moore, GP; Nelson, DR; Trout, A, 1997) |
"Severe respiratory depression and somnolence supervened 3." | 1.30 | [Persisting respiratory depression following intrathecal administration of morphine and simultaneous sedation with midazolam]. ( Büttner, T; Dworzak, H; Fuss, F, 1999) |
"The fentanyl infusion was decreased by 1 microg/kg/hr every 12-24 hrs and the midazolam infusion was decreased by 0." | 1.30 | Subcutaneous administration of fentanyl and midazolam to prevent withdrawal after prolonged sedation in children. ( Tobias, JD, 1999) |
"Midazolam was the intravenous sedative used by a third of all respondents and 13% also used an additional intravenous agent, usually pethidine." | 1.28 | Sedation for upper gastrointestinal endoscopy: results of a nationwide survey. ( Bell, GD; Daneshmend, TK; Logan, RF, 1991) |
"Fourteen patients developed hypoxemia of less than 60 mm Hg on FIO2 adjusted to 0." | 1.28 | Fiberoptic bronchoscopy in ventilated patients. Evaluation of cardiopulmonary risk under midazolam sedation. ( Blanchet, F; Chastre, J; Dreyfuss, D; Fagon, JY; Gibert, C; Guiguet, M; Trouillet, JL, 1990) |
"Because of the prevalence of substance abuse, cocaine use should be considered in the differential diagnosis of sudden cardiovascular compromise in parturients." | 1.28 | Anaesthetic management of a parturient with myocardial infarction related to cocaine use. ( Chen, K; Forrester, RM; Glassenberg, R; Liu, SS; Murphy, GS, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (10.39) | 18.7374 |
1990's | 15 (19.48) | 18.2507 |
2000's | 20 (25.97) | 29.6817 |
2010's | 27 (35.06) | 24.3611 |
2020's | 7 (9.09) | 2.80 |
Authors | Studies |
---|---|
Sadozai, L | 1 |
Prot-Labarthe, S | 1 |
Bourdon, O | 1 |
Dauger, S | 1 |
Deho, A | 1 |
Yao, J | 1 |
Hao, S | 1 |
Zhou, C | 1 |
Cao, Y | 1 |
Quan, Z | 1 |
Yazawa, N | 1 |
Nakamura, Y | 1 |
Takemasa, A | 1 |
Uchida, N | 1 |
Kushima, Y | 1 |
Masawa, M | 1 |
Okutomi, H | 1 |
Soda, S | 1 |
Ikeda, N | 1 |
Arai, R | 1 |
Chibana, K | 1 |
Niho, S | 1 |
Shimizu, Y | 1 |
Cosentino, G | 1 |
Romano, M | 1 |
Algeri, M | 1 |
Brighina, F | 1 |
Alfonsi, E | 1 |
Tassorelli, C | 1 |
Crescimanno, G | 1 |
Wang, L | 1 |
Zhang, T | 1 |
Huang, L | 1 |
Peng, W | 1 |
Inata, Y | 1 |
Sofue, T | 1 |
Hatachi, T | 1 |
Kyogoku, M | 1 |
Takeuchi, M | 1 |
Dallefeld, SH | 1 |
Smith, PB | 1 |
Crenshaw, EG | 1 |
Daniel, KR | 1 |
Gilleskie, ML | 1 |
Smith, DS | 1 |
Balevic, S | 1 |
Greenberg, RG | 1 |
Chu, V | 1 |
Clark, R | 1 |
Kumar, KR | 1 |
Zimmerman, KO | 1 |
Vargas, N | 1 |
Tibullo, L | 1 |
Landi, CAE | 1 |
Carifi, G | 1 |
Landi, E | 1 |
Salsano, E | 1 |
Di Grezia, F | 1 |
Candelmo, F | 1 |
Tsukamoto, A | 2 |
Konishi, Y | 1 |
Kawakami, T | 1 |
Koibuchi, C | 1 |
Sato, R | 2 |
Kanai, E | 1 |
Inomata, T | 2 |
Liou, JY | 1 |
Ting, CK | 1 |
Teng, WN | 1 |
Mandell, MS | 1 |
Tsou, MY | 1 |
Yamaguchi, S | 1 |
Kitamura, J | 1 |
Inatomi, O | 1 |
Imai, T | 1 |
Fujimoto, T | 1 |
Takahashi, K | 2 |
Yokota, Y | 1 |
Yamashita, N | 1 |
Hasegawa, H | 1 |
Nishida, A | 1 |
Bamba, S | 1 |
Sugimoto, M | 1 |
Andoh, A | 1 |
Afzal, A | 1 |
Kiyatkin, EA | 1 |
Giroud, M | 1 |
Sellier, E | 1 |
Laval, G | 1 |
Mittal, N | 1 |
Goyal, A | 1 |
Gauba, K | 1 |
Kapur, A | 1 |
Jain, K | 1 |
Devlin, JW | 1 |
Al-Qadheeb, NS | 1 |
Chi, A | 1 |
Roberts, RJ | 1 |
Qawi, I | 1 |
Garpestad, E | 1 |
Hill, NS | 1 |
Ideno, S | 1 |
Miyazawa, N | 1 |
Ishikawa, S | 1 |
Wakamiya, R | 1 |
Shinto, A | 1 |
Mikasa, H | 1 |
Yamamoto, S | 1 |
Smith, AL | 1 |
Owen, H | 1 |
Reynolds, KJ | 1 |
Silva, RA | 1 |
Leng, JC | 1 |
He, L | 1 |
Brock-Utne, JG | 1 |
Drover, DR | 1 |
Leng, T | 1 |
Iimuro, M | 1 |
Yamazaki, J | 1 |
Weingarten, TN | 1 |
Bergan, TS | 1 |
Narr, BJ | 1 |
Schroeder, DR | 1 |
Sprung, J | 1 |
Ersoy, A | 1 |
Kara, D | 1 |
Ervatan, Z | 1 |
Çakırgöz, M | 1 |
Kıran, Ö | 1 |
Ninomiya, A | 1 |
Matsuura, N | 1 |
Ichinohe, T | 1 |
Gonzalez Castro, LN | 1 |
Mehta, JH | 1 |
Brayanov, JB | 1 |
Mullen, GJ | 1 |
Mayordomo-Colunga, J | 1 |
Medina, A | 1 |
Rey, C | 1 |
Díaz, JJ | 1 |
Concha, A | 1 |
Los Arcos, M | 1 |
Menéndez, S | 1 |
Gläser, M | 1 |
Kohlhaas, K | 1 |
Tegenthoff, M | 1 |
Maier, C | 1 |
Mizrak, A | 1 |
Koruk, S | 1 |
Ganidagli, S | 1 |
Bulut, M | 1 |
Oner, U | 1 |
Supady, A | 1 |
Schwab, T | 1 |
Busch, HJ | 1 |
Dreher, M | 1 |
Ekkernkamp, E | 1 |
Storre, JH | 1 |
Kabitz, HJ | 1 |
Windisch, W | 1 |
Lee, P | 1 |
Mathur, PN | 1 |
Gresham, C | 1 |
Ruha, AM | 1 |
Watanabe, K | 1 |
Chin, K | 1 |
Murata, M | 1 |
Doi, H | 1 |
Handa, T | 1 |
Oga, T | 1 |
Tsuboi, T | 1 |
Ikeda, T | 1 |
Nakahata, T | 1 |
Sakata, R | 1 |
Mishima, M | 1 |
Carmi, U | 1 |
Kramer, MR | 1 |
Zemtzov, D | 1 |
Rosengarten, D | 1 |
Fruchter, O | 1 |
Wilson, KE | 1 |
Thorpe, RJ | 1 |
McCabe, JF | 1 |
Girdler, NM | 1 |
da Silva, PS | 1 |
Passos, RM | 1 |
Waisberg, DR | 1 |
Salukhe, TV | 1 |
Willems, S | 1 |
Drewitz, I | 1 |
Steven, D | 1 |
Hoffmann, BA | 1 |
Heitmann, K | 1 |
Rostock, T | 1 |
Shekar, K | 1 |
Roberts, JA | 1 |
Mullany, DV | 1 |
Corley, A | 1 |
Fisquet, S | 1 |
Bull, TN | 1 |
Barnett, AG | 1 |
Fraser, JF | 1 |
De La Mora-González, JF | 1 |
Robles-Cervantes, JA | 1 |
Mora-Martínez, JM | 1 |
Barba-Alvarez, F | 1 |
Llontop-Pisfil, Ede L | 1 |
González-Ortiz, M | 1 |
Martínez-Abundis, E | 1 |
Llamas-Moreno, JF | 1 |
Espinel Bermúdez, MC | 1 |
Izurieta, R | 1 |
Rabatin, JT | 1 |
Ferson, D | 1 |
Thakar, D | 1 |
Swafford, J | 1 |
Sinha, A | 1 |
Sapire, K | 1 |
Arens, J | 1 |
Aretz, S | 1 |
Licht, C | 1 |
Roth, B | 1 |
Yldzdaş, D | 1 |
Yapcoǧlu, H | 1 |
Ylmaz, HL | 1 |
Mizuno, J | 1 |
Nakano, M | 1 |
Kasuya, M | 1 |
Nishiyama, T | 1 |
Hanaoka, K | 1 |
Ozdemir, D | 1 |
Gulez, P | 1 |
Uran, N | 1 |
Yendur, G | 1 |
Kavakli, T | 1 |
Aydin, A | 1 |
Martel, M | 1 |
Sterzinger, A | 1 |
Miner, J | 1 |
Clinton, J | 1 |
Biros, M | 1 |
Edwards, MJ | 1 |
Maruyama, S | 1 |
Nomura, Y | 1 |
Fukushige, T | 1 |
Eguchi, T | 1 |
Nishi, J | 1 |
Yoshinaga, M | 1 |
Kawano, Y | 1 |
Deitch, K | 1 |
Chudnofsky, CR | 1 |
Dominici, P | 1 |
Li, Y | 2 |
Zhang, WC | 1 |
Postovsky, S | 1 |
Moaed, B | 1 |
Krivoy, E | 1 |
Ofir, R | 1 |
Ben Arush, MW | 1 |
Parviainen, I | 1 |
Kälviäinen, R | 1 |
Ruokonen, E | 1 |
Byatt, CM | 1 |
Lewis, LD | 1 |
Dawling, S | 1 |
Cochrane, GM | 1 |
Castillo, J | 1 |
Bisbe, E | 1 |
Sierra, P | 1 |
Escolano, F | 1 |
Castaño, J | 1 |
Mainwaring, CJ | 1 |
Wong, C | 1 |
Lush, RJ | 1 |
Smith, JG | 1 |
Singer, CR | 1 |
Heniff, MS | 1 |
Moore, GP | 1 |
Trout, A | 1 |
Cordell, WH | 1 |
Nelson, DR | 1 |
Davis, DP | 1 |
Hamilton, RS | 1 |
Webster, TH | 1 |
Dworzak, H | 1 |
Fuss, F | 1 |
Büttner, T | 1 |
Tobias, JD | 2 |
Prause, A | 1 |
Wappler, F | 1 |
Scholz, J | 1 |
Bause, H | 1 |
Schulte am Esch, J | 1 |
Crofts, TR | 1 |
Monagle, J | 1 |
Buist, M | 1 |
Burnes, J | 1 |
Berkenbosch, JW | 1 |
Liu, SS | 1 |
Forrester, RM | 1 |
Murphy, GS | 1 |
Chen, K | 1 |
Glassenberg, R | 1 |
Classen, DC | 1 |
Pestotnik, SL | 1 |
Evans, RS | 1 |
Burke, JP | 1 |
Alexander, CM | 1 |
Teller, LE | 1 |
Gross, JB | 2 |
Weller, RS | 1 |
Conard, P | 1 |
Traynor, LA | 1 |
Daneshmend, TK | 1 |
Bell, GD | 2 |
Logan, RF | 1 |
Raine, J | 1 |
Warner, JO | 1 |
Trouillet, JL | 1 |
Guiguet, M | 1 |
Gibert, C | 1 |
Fagon, JY | 1 |
Dreyfuss, D | 1 |
Blanchet, F | 1 |
Chastre, J | 1 |
Carter, AS | 1 |
Coady, T | 1 |
Lee, J | 1 |
Morden, A | 1 |
Lim, AG | 1 |
Hyatt, J | 1 |
Coro, C | 1 |
Bergman, SA | 1 |
Wynn, RL | 1 |
Tilly-Kiesi, M | 1 |
Perttunen, K | 1 |
Somer, T | 1 |
Pentikäinen, PJ | 1 |
Dixon, D | 1 |
Wild, A | 1 |
Bertolaso, E | 1 |
Lineaweaver, WC | 1 |
Anderson, K | 1 |
Hing, DN | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Triple Drug Response Surface Modeling for Patients Receiving Airway Managements[NCT03813875] | 100 participants (Actual) | Observational | 2019-06-12 | Completed | |||
The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia[NCT05525351] | 60 participants (Anticipated) | Observational | 2022-10-31 | Not yet recruiting | |||
The Efficacy and Safety of Gastric Feeding in Critically Ill Pediatric Patients Receiving Non-invasive Positive Pressure Ventilation: A Pilot Study[NCT01301352] | 30 participants (Actual) | Interventional | 2011-02-28 | Completed | |||
Effect of BIS Monitoring on Propofol Usage During Elective Bronchoscopy[NCT01592513] | 80 participants (Anticipated) | Interventional | 2012-04-30 | Recruiting | |||
High Flow Nasal Cannula (HFNC) Versus Standard Low Flow Nasal Cannula (LFNC) in Patients With Atrial Fibrillation Undergoing Radiofrequency Catheter Ablation (RFCA) Under Deep Desaturation.[NCT04842253] | 210 participants (Anticipated) | Interventional | 2022-01-04 | Recruiting | |||
A Pilot Study to Investigate the Efficacy and Safety of Dexmedetomidine and Fentanyl Versus Midazolam and Remifentanil for Sedation in Patients Undergoing Ablation Procedures for Treatment of a Tachyarrhythmia[NCT03451227] | 6 participants (Actual) | Interventional | 2017-12-01 | Terminated (stopped due to Unable to recruit eligible participants) | |||
Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane[NCT05680545] | 10 participants (Anticipated) | Interventional | 2024-07-01 | Not yet recruiting | |||
Supraglottic Airway Use for Transesophageal Echocardiography: a Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease. (SGA-TEE)[NCT04939220] | 110 participants (Anticipated) | Interventional | 2024-02-29 | Not yet recruiting | |||
Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915] | 314 participants (Actual) | Observational | 2017-08-01 | Completed | |||
Effect of High Flow Nasal Cannula vs. Standard Care on Respiratory Stability in Pediatric Procedural Sedation: A Randomized Controlled Pilot Trial[NCT02930525] | 50 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in Critically Ill Ventilated Patients: Impact on Respiratory Mechanics and Gas Exchange[NCT04502368] | 15 participants (Anticipated) | Observational | 2020-09-01 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
5 reviews available for midazolam and Respiratory Insufficiency
Article | Year |
---|---|
Sedation during mechanical ventilation: a systematic review.
Topics: Adult; Anesthetics; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Pro | 2002 |
Opioids and benzodiazepines appear paradoxically to delay inevitable death after ventilator withdrawal.
Topics: Adult; Aged; Analgesics, Opioid; Analysis of Variance; Anti-Anxiety Agents; Conscious Sedation; Cons | 2005 |
Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and cons.
Topics: Anesthetics, Intravenous; Anticonvulsants; Barbiturates; Dose-Response Relationship, Drug; Humans; M | 2007 |
Reversal of midazolam-induced laryngospasm with flumazenil.
Topics: Anti-Anxiety Agents; Antidotes; Conscious Sedation; Electric Countershock; Flumazenil; GABA Modulato | 1998 |
Midazolam--is antagonism justified?
Topics: Adult; Aged; Cardiovascular Diseases; Flumazenil; Humans; Midazolam; Respiratory Insufficiency | 1988 |
17 trials available for midazolam and Respiratory Insufficiency
Article | Year |
---|---|
Application of low-dose etomidate combined with oxycodone and midazolam in endoscopic injection sclerotherapy.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Etomidate; Humans; Hypoxia; Midazolam; Middle Age | 2023 |
Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery.
Topics: Aged; Bradycardia; Conscious Sedation; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Seda | 2020 |
A double blind randomized trial of ketofol versus propofol for endodontic treatment of anxious pediatric patients.
Topics: Child; Child, Preschool; Dental Anxiety; Double-Blind Method; Drug Combinations; Female; Humans; Hyp | 2013 |
Efficacy and safety of early dexmedetomidine during noninvasive ventilation for patients with acute respiratory failure: a randomized, double-blind, placebo-controlled pilot study.
Topics: Acute Disease; Administration, Intravenous; Aged; Aged, 80 and over; Dexmedetomidine; Dose-Response | 2014 |
Sedation in hypoalbuminemic geriatric patients under spinal anesthesia in hip surgery. Midazolam or Propofol?
Topics: Age Factors; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Spinal; Arthroplasty, | 2015 |
Inhalation of 50% Oxygen Does Not Impair Respiratory Depression During Midazolam Sedation.
Topics: Adult; Antidotes; Capnography; Conscious Sedation; Cross-Over Studies; Female; Flumazenil; Healthy V | 2016 |
Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy.
Topics: Adult; Anesthesia; Bipolar Disorder; Blood Pressure; Depressive Disorder, Major; Dexmedetomidine; El | 2009 |
Propofol safety in bronchoscopy: prospective randomized trial using transcutaneous carbon dioxide tension monitoring.
Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia Recovery Period; Anesthetics, Intravenous; Bl | 2011 |
Hemodynamic effects of dexmedetomidine--fentanyl vs. nalbuphine--propofol in plastic surgery.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Blood Pressure; Dexmedetomidine; Drug Therapy, Combina | 2012 |
The value of capnography during sedation or sedation/analgesia in pediatric minor procedures.
Topics: Adolescent; Analgesia; Analgesics; Capnography; Carbon Dioxide; Child; Child, Preschool; Conscious S | 2004 |
Efficacy of continuous midazolam infusion and mortality in childhood refractory generalized convulsive status epilepticus.
Topics: Adolescent; Bradycardia; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Hypn | 2005 |
Management of acute undifferentiated agitation in the emergency department: a randomized double-blind trial of droperidol, ziprasidone, and midazolam.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Antipsychotic Agents; Dose-Response Relationship, Drug | 2005 |
The utility of supplemental oxygen during emergency department procedural sedation and analgesia with midazolam and fentanyl: a randomized, controlled trial.
Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Capnography; Child; Child, Preschool; Consci | 2007 |
[Effects of acupuncture in Siguan points on man-machine counteraction in respiratory failure patients during mechanical ventilation].
Topics: Acupuncture Points; Acupuncture Therapy; Adolescent; Adult; Combined Modality Therapy; Female; GABA | 2006 |
Slow injection does not prevent midazolam-induced ventilatory depression.
Topics: Adult; Carbon Dioxide; Double-Blind Method; Humans; Injections, Intravenous; Male; Midazolam; Random | 1992 |
Flumazenil antagonism of midazolam-induced ventilatory depression.
Topics: Adult; Blood Pressure; Double-Blind Method; Flumazenil; Heart Rate; Humans; Injections, Intravenous; | 1991 |
[Is there a risk of global respiratory insufficiency with the use of intramuscular midazolam as premedication for bronchoscopy?].
Topics: Blood Gas Analysis; Bronchoscopy; Fiber Optic Technology; Humans; Hydrocodone; Injections, Intramusc | 1988 |
55 other studies available for midazolam and Respiratory Insufficiency
Article | Year |
---|---|
Use of continuous infusion of clonidine for sedation in critically ill infants and children.
Topics: Bradycardia; Child, Preschool; Clonidine; Critical Care; Critical Illness; Female; Humans; Hypnotics | 2022 |
Transcutaneous gas monitoring is a useful tool to detect respiratory depression during bronchoscopy performed under propofol sedation.
Topics: Bronchoscopy; Carbon Dioxide; Conscious Sedation; Fentanyl; Humans; Hypnotics and Sedatives; Midazol | 2023 |
Intranasal midazolam for treating acute respiratory crises in a woman with stiff person syndrome.
Topics: Administration, Intranasal; Benzodiazepines; Dyspnea; Female; Humans; Midazolam; Middle Aged; Respir | 2020 |
Prone positioning without neuromuscular blockade during extracorporeal membrane oxygenation in children.
Topics: Adolescent; Child; Child, Preschool; Chlorpromazine; Dexmedetomidine; Extracorporeal Membrane Oxygen | 2020 |
Comparative safety profile of chloral hydrate versus other sedatives for procedural sedation in hospitalized infants.
Topics: Chloral Hydrate; Diagnostic Imaging; Diagnostic Techniques, Ophthalmological; Electroencephalography | 2020 |
Slow ventricular tachycardia in a 91-year-old man with implantable cardioverter-defibrillator and acute respiratory failure.
Topics: Aged, 80 and over; Continuous Positive Airway Pressure; Defibrillators, Implantable; Humans; Hypnoti | 2017 |
Pharmacological properties of various anesthetic protocols in 10-day-old neonatal rats.
Topics: Anesthesia; Anesthetics, Combined; Animals; Animals, Newborn; Butorphanol; Dose-Response Relationshi | 2017 |
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug S | 2018 |
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug S | 2018 |
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug S | 2018 |
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug S | 2018 |
[Evaluation of Anesthesia Method to Minimize Intraoperative Body Movement and Respiratory Depression for Dilatation and Curettage A Retrospective Study].
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Dental; Dilatation and Curettage; Female; Fentanyl; H | 2016 |
Dexmedetomidine is safe and reduces the additional dose of midazolam for sedation during endoscopic retrograde cholangiopancreatography in very elderly patients.
Topics: Aged, 80 and over; Blood Pressure; Cholangiopancreatography, Endoscopic Retrograde; Dexmedetomidine; | 2018 |
Interactions of benzodiazepines with heroin: Respiratory depression, temperature effects, and behavior.
Topics: Animals; Asphyxia; Behavior, Animal; Body Temperature; Brain; Drug Interactions; Electrodes, Implant | 2019 |
[Use of midazolam in hospitalized patients: analysis of medical practice].
Topics: Aged; Aged, 80 and over; Anxiety; Female; France; Hospitalization; Humans; Hypnotics and Sedatives; | 2013 |
[Anesthetic management of a patient with severe subcutaneous and mediastinal emphysema due to pertussis infection].
Topics: Airway Management; Anesthesia; Drainage; Extracorporeal Membrane Oxygenation; Female; Humans; Infant | 2014 |
Can short-term heart rate variability be used to monitor fentanyl-midazolam induced changes in ANS preceding respiratory depression?
Topics: Adolescent; Adult; Aged; Analgesics; Analgesics, Opioid; Autonomic Nervous System; Electrocardiograp | 2015 |
Risk factors for respiratory depression in patients undergoing retrobulbar block for vitreoretinal surgery.
Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia, Conduction; Anesthetics, Combined; Anestheti | 2015 |
Effect of midazolam and butorphanol premedication on inhalant isoflurane anesthesia in mice.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Animals, Laboratory; Butorphanol; Isoflura | 2015 |
Effects of changes in intraoperative management on recovery from anesthesia: a review of practice improvement initiative.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Antiemetics; | 2015 |
Quantification of respiratory depression during pre-operative administration of midazolam using a non-invasive respiratory volume monitor.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia; Female; Humans; Lung Volume Measurements; Male; Midazola | 2017 |
Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study.
Topics: Adolescent; Anti-Anxiety Agents; Anxiety; Asthma; Bronchiolitis; Child; Child, Preschool; Critical I | 2009 |
[Life-threatening respiratory depression after pain therapy].
Topics: Adult; Analgesics; Anesthetics, Local; Arm Injuries; Female; Humans; Hypnotics and Sedatives; Mepiva | 2008 |
["Liquid ecstasy": gamma-butyrolactone withdrawal delirium with rhabdomyolysis and dialysis dependent renal failure].
Topics: 4-Butyrolactone; Acute Kidney Injury; Adrenergic alpha-Agonists; Benzodiazepines; Clonidine; GABA Mo | 2009 |
Sedation during flexible bronchoscopy in patients with pre-existing respiratory failure: Midazolam versus Midazolam plus Alfentanil.
Topics: Adult; Aged; Alfentanil; Anesthesia Recovery Period; Anesthetics, Intravenous; Blood Gas Monitoring, | 2010 |
Safe to sedate for bronchoscopy despite respiratory failure.
Topics: Alfentanil; Anesthetics, Intravenous; Bronchoscopy; Humans; Midazolam; Respiratory Insufficiency | 2010 |
Respiratory failure following isolated ziprasidone ingestion in a toddler.
Topics: Accidents; Antipsychotic Agents; Chromatography, Liquid; Humans; Hypnotics and Sedatives; Infant; In | 2010 |
Avoidance of reintubation by using sedation during noninvasive positive pressure ventilation in a 3-month-old infant with postoperative respiratory failure.
Topics: Chlorpromazine; Deep Sedation; Humans; Infant; Intubation, Intratracheal; Male; Midazolam; Positive- | 2010 |
Complications associated with intravenous midazolam sedation in anxious dental patients.
Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthetics, Intravenous; Child; Clinical Audit; Consci | 2011 |
Withdrawal treatment with clonidine after prolonged use of chloral hydrate in a pediatric intensive care patient.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Chloral Hydrate; Clonidine; Fentanyl; Humans; Hypnoti | 2011 |
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St | 2012 |
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St | 2012 |
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St | 2012 |
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St | 2012 |
Increased sedation requirements in patients receiving extracorporeal membrane oxygenation for respiratory and cardiorespiratory failure.
Topics: Adolescent; Adult; Aged; APACHE; Extracorporeal Membrane Oxygenation; Female; Heart Failure; Humans; | 2012 |
Use of deep intravenous sedation with propofol and the laryngeal mask airway during transesophageal echocardiography.
Topics: Adult; Aged; Airway Obstruction; Anesthesiology; Anesthetics, Intravenous; Cardiology; Drug Therapy, | 2003 |
Endogenous distress in ventilated full-term newborns with acute respiratory failure.
Topics: Acute Disease; Analgesia; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant, Newborn; Intens | 2004 |
[A case of giant thyroid tumor with tracheal stenosis].
Topics: Anesthesia, General; Conscious Sedation; Female; Fentanyl; Humans; Intubation, Intratracheal; Midazo | 2004 |
Suspected takotsubo cardiomyopathy caused by withdrawal of bupirenorphine in a child.
Topics: Age Factors; Analgesics, Opioid; Buprenorphine; Cardiomyopathies; Child, Preschool; Echocardiography | 2006 |
Practice of palliative sedation in children with brain tumors and sarcomas at the end of life.
Topics: Adolescent; Bone Neoplasms; Brain Neoplasms; Child; Combined Modality Therapy; Consciousness; Glioma | 2007 |
Accumulation of midazolam after repeated dosage in patients receiving mechanical ventilation in an intensive care unit.
Topics: Aged; Anesthetics; Benzodiazepines; Child, Preschool; Dose-Response Relationship, Drug; Female; Huma | 1984 |
[Prolonged sedation with midazolam in critically ill patients undergoing artificial ventilation].
Topics: Aged; Aged, 80 and over; APACHE; Blood Pressure; Body Weight; Critical Care; Dose-Response Relations | 1995 |
The role of midazolam-induced sedation in bone marrow aspiration/trephine biopsies.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Antidotes; Awareness; Bone Marrow; Conscious Sedation; | 1996 |
Comparison of routes of flumazenil administration to reverse midazolam-induced respiratory depression in a canine model.
Topics: Administration, Rectal; Administration, Sublingual; Animals; Antidotes; Cross-Over Studies; Disease | 1997 |
[Persisting respiratory depression following intrathecal administration of morphine and simultaneous sedation with midazolam].
Topics: Aged; Analgesics, Opioid; Flumazenil; Humans; Hypnotics and Sedatives; Injections, Spinal; Intubatio | 1999 |
Subcutaneous administration of fentanyl and midazolam to prevent withdrawal after prolonged sedation in children.
Topics: Analgesics, Opioid; Body Weight; Child; Child, Preschool; Conscious Sedation; Fentanyl; Humans; Hypn | 1999 |
Respiratory depression under long-term sedation with sufentanil, midazolam and clonidine has no clinical significance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Intravenous; Carbon Dioxide; Ch | 2000 |
Bilateral frontal haemorrhages associated with continuous spinal analgesia.
Topics: Adjuvants, Anesthesia; Aged; Analgesia, Epidural; Cerebral Hemorrhage; Fatal Outcome; Humans; Male; | 2001 |
Tolerance during sedation in a pediatric ICU patient: effects on the BIS monitor.
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthetics; Anesthetics, Intravenous; Child; Down Syndrome; Drug | 2001 |
Anaesthetic management of a parturient with myocardial infarction related to cocaine use.
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Crack Cocaine; Female; Fentanyl; Humans; La | 1992 |
Intensive surveillance of midazolam use in hospitalized patients and the occurrence of cardiorespiratory arrest.
Topics: Aged; Drug Monitoring; Drug Utilization; Female; Heart Arrest; Hospitalization; Hospitals, Teaching; | 1992 |
Midazolam-fentanyl sedation.
Topics: Child; Child, Preschool; Drug Synergism; Fentanyl; Humans; Midazolam; Respiratory Insufficiency | 1991 |
Sedation for upper gastrointestinal endoscopy: results of a nationwide survey.
Topics: Benzodiazepines; Conscious Sedation; Endoscopy, Gastrointestinal; Heart Arrest; Humans; Hypoventilat | 1991 |
Fibreoptic bronchoscopy without general anaesthetic.
Topics: Adolescent; Adult; Anesthesia, Local; Bronchoscopes; Bronchoscopy; Child; Child, Preschool; Consciou | 1991 |
Fiberoptic bronchoscopy in ventilated patients. Evaluation of cardiopulmonary risk under midazolam sedation.
Topics: Adult; Aged; Aged, 80 and over; Bronchoscopy; Carbon Dioxide; Female; Hemodynamics; Humans; Hydrogen | 1990 |
Speed of reversal of midazolam-induced respiratory depression by flumazenil--a study in patients undergoing upper G.I. endoscopy.
Topics: Adult; Aged; Aged, 80 and over; Blood Gas Monitoring, Transcutaneous; Female; Flumazenil; Gastroscop | 1990 |
Death after flumazenil.
Topics: Aged; Aged, 80 and over; Antidotes; Female; Flumazenil; Humans; Midazolam; Respiratory Insufficiency | 1989 |
Effects of midazolam on fentanyl antinociception and respiration in a rabbit model.
Topics: Analgesics; Animals; Carbon Dioxide; Drug Combinations; Electric Stimulation; Female; Fentanyl; Infu | 1989 |
[Midazolam causing respiratory arrest and hypotension].
Topics: Humans; Hypotension; Male; Midazolam; Middle Aged; Respiratory Insufficiency | 1989 |
Respiratory depression following midazolam.
Topics: Aged; Benzodiazepines; Humans; Hypnotics and Sedatives; Male; Midazolam; Respiratory Insufficiency | 1985 |
Massive doses of midazolam infusion for delirium tremens without respiratory depression.
Topics: Adult; Alcohol Withdrawal Delirium; Amputation, Traumatic; Finger Injuries; Humans; Infusions, Intra | 1988 |