midazolam has been researched along with Respiration Disorders in 5 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Respiration Disorders: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was designed to: 1) compare the safety and efficacy of intravenous fentanyl, intravenous fentanyl combined with midazolam, and intramuscular meperidine-promethazine-chlorpromazine (MPC) compound when used for painful emergency department (ED) procedures: and 2) to determine whether the addition of et-CO2 monitoring enabled earlier identification of respiratory depression in this population." | 5.08 | The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department. ( Berns, SD; Boenning, DA; Hart, LS; Houck, CS, 1997) |
| "To determine the incidence of adverse events related to an endoscopy sedation regimen that included propofol, delivered by general practitioner (GP) sedationists." | 1.31 | Sedation for endoscopy: the safe use of propofol by general practitioner sedationists. ( Chiragakis, L; Clarke, AC; Hillman, LC; Kaye, GL, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Godambe, SA | 1 |
| Elliot, V | 1 |
| Matheny, D | 1 |
| Pershad, J | 1 |
| Revesz, T | 1 |
| Orban, T | 1 |
| DeBuse, P | 1 |
| Nagahama, H | 1 |
| Kikuchi, S | 1 |
| Shimazaki, K | 1 |
| Tateda, T | 1 |
| Aoki, T | 1 |
| Takahashi, K | 1 |
| Hart, LS | 1 |
| Berns, SD | 1 |
| Houck, CS | 1 |
| Boenning, DA | 1 |
| Clarke, AC | 1 |
| Chiragakis, L | 1 |
| Hillman, LC | 1 |
| Kaye, GL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Two Methods Using Intranasal Lidocaine to Alleviate Discomfort Associated With Administration of Intranasal Midazolam in Children.[NCT03054844] | Phase 2 | 55 participants (Actual) | Interventional | 2017-04-03 | Completed | ||
| A Prospective Randomized Double Blind Evaluation of Ketamine/Propofol vs Ketamine Alone for Pediatric Extremity Fracture Reduction[NCT00490997] | Phase 4 | 140 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions[NCT00596050] | Phase 4 | 50 participants (Actual) | Interventional | 2006-08-31 | Completed | ||
| Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090] | Phase 3 | 30 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| A Randomised Control Trial to Determine Whether Intervention Based on a Microstream Capnography-based Ventilation Monitoring System Will Decrease Hypoxaemaia During Intravenous Sedation With Midazolam.[NCT01949012] | 190 participants (Actual) | Interventional | 2013-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
If my child needed medications to stay calm for a procedure, I would like to use these same medications again. (NCT03054844)
Timeframe: 1 minute
| Intervention | Participants (Count of Participants) |
|---|---|
| PREMED | 10 |
| PREMIX | 12 |
Cry duration was measured in seconds and defined as the time from onset of crying following administration of an IN medication until the cessation of crying sounds and/or tears. If a patient did not cry, the cry duration was zero (NCT03054844)
Timeframe: 10 minutes
| Intervention | seconds (Mean) |
|---|---|
| PREMED | 84 |
| PREMIX | 73 |
The Faces, Legs, Activity, Cry, Consolability (FLACC) scale is comprised of five criteria (face, legs, activity, cry, consolability), with a possible score of 0 to 2 units on a scale for each criteria and a possible total score of 0 to 10 units on a scale (0 meaning no pain, 10 meaning most pain). (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 6.7 |
| PREMIX | 7 |
The Observational Scale of Behavioral Distress-Revised (OSBD-R) is an observational measure of pain and distress shown to have strong validity in children. The scale is an 8-factor, weighted observational scale used to measure distress associated with medical procedures, which has been validated in children and adults aged 1 to 20 years. The total Observational Scale of Behavioral Distress-Revised score is the sum of the scale scores for each phase, with each phase assigned a score from 0 to 23.5 units on a scale (0=no distress, 23.5=maximum distress), based on the frequency and types of behaviors observed during a predetermined number of 15-second intervals during each phase. There were four phases so the range of scores for the total OSBD-R was 0 to 94 units on a scale, with a higher score indicated a greater degree of distress. (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 6.4 |
| PREMIX | 7 |
The Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) utilizes six observational factors (cry, facial, verbal, torso, touch, and legs) to evaluate pain in young children and can be used to monitor the effectiveness of interventions for reducing the pain and discomfort of an intervention. This scale rates each behavior numerically, with a score of 4-6 units on a scale representing no pain, and a maximum score of 13 units on a scale representing (most pain perceived). (NCT03054844)
Timeframe: 10 minutes
| Intervention | Units on a scale (Mean) |
|---|---|
| PREMED | 10.6 |
| PREMIX | 10.5 |
I would like to use this method of administering intranasal midazolam and lidocaine again in the future (NCT03054844)
Timeframe: 1 minute
| Intervention | Participants (Count of Participants) |
|---|---|
| PREMED | 8 |
| PREMIX | 24 |
3 trials available for midazolam and Respiration Disorders
| Article | Year |
|---|---|
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
Comparison of propofol/fentanyl versus ketamine/midazolam for brief orthopedic procedural sedation in a pediatric emergency department.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Drug Combinations; Emergencies; Emergency S | 2003 |
[The use of low dose midazolam for the management of spinal anesthesia].
Topics: Adolescent; Adult; Aged; Anesthesia, Spinal; Anti-Anxiety Agents; Dose-Response Relationship, Drug; | 1996 |
The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department.
Topics: Capnography; Carbon Dioxide; Child; Chlorpromazine; Conscious Sedation; Drug Combinations; Emergency | 1997 |
2 other studies available for midazolam and Respiration Disorders
| Article | Year |
|---|---|
Transient respiratory depression in two patients with Down's syndrome following Midazolam premedication.
Topics: Down Syndrome; Humans; Male; Midazolam; Premedication; Respiration Disorders | 1993 |
Sedation for endoscopy: the safe use of propofol by general practitioner sedationists.
Topics: Anesthetics, Combined; Anesthetics, Intravenous; Australia; Colonoscopy; Family Practice; Fentanyl; | 2002 |