Page last updated: 2024-10-31

midazolam and Preterm Birth

midazolam has been researched along with Preterm Birth in 3 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
" Developing modelling and simulation tools, such as physiologically based pharmacokinetic (PBPK) models that incorporate developmental physiology and maturation of drug metabolism, can be used to predict drug exposure in this group of patients, and may help to optimize drug dose adjustment."2.94Preterm Physiologically Based Pharmacokinetic Model. Part II: Applications of the Model to Predict Drug Pharmacokinetics in the Preterm Population. ( Abduljalil, K; Jamei, M; Johnson, TN; Pan, X; Pansari, A, 2020)
"Current therapeutic options to treat neonatal seizures (i."2.49Treatment of neonatal seizures. ( de Vries, LS; Hellström-Westas, L; van Rooij, LG, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Abduljalil, K1
Pan, X1
Pansari, A1
Jamei, M1
Johnson, TN1
Djabri, A1
Guy, RH1
Delgado-Charro, MB1
van Rooij, LG1
Hellström-Westas, L1
de Vries, LS1

Reviews

1 review available for midazolam and Preterm Birth

ArticleYear
Treatment of neonatal seizures.
    Seminars in fetal & neonatal medicine, 2013, Volume: 18, Issue:4

    Topics: Animals; Anticonvulsants; Brain; Child Development; Drug Resistance; Epilepsy; Humans; Infant, Newbo

2013

Trials

1 trial available for midazolam and Preterm Birth

ArticleYear
Preterm Physiologically Based Pharmacokinetic Model. Part II: Applications of the Model to Predict Drug Pharmacokinetics in the Preterm Population.
    Clinical pharmacokinetics, 2020, Volume: 59, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Alfentanil; Anti-Bacterial Agents; Caffeine; Comp

2020

Other Studies

1 other study available for midazolam and Preterm Birth

ArticleYear
Potential of iontophoresis as a drug delivery method for midazolam in pediatrics.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Feb-01, Volume: 128

    Topics: Administration, Cutaneous; Drug Delivery Systems; Humans; Hypnotics and Sedatives; Infant, Newborn;

2019