Page last updated: 2024-10-31

midazolam and Plasmodium falciparum Malaria

midazolam has been researched along with Plasmodium falciparum Malaria in 2 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
" Plasma concentration-time data were fitted using pharmacokinetic models."2.73Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions. ( Edwards, G; Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR; Ward, SA, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Muchohi, SN2
Kokwaro, GO2
Ogutu, BR1
Edwards, G2
Ward, SA2
Newton, CR2
Preston, L1

Trials

1 trial available for midazolam and Plasmodium falciparum Malaria

ArticleYear
Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:4

    Topics: Administration, Buccal; Adolescent; Africa; Anticonvulsants; Child; Child, Preschool; Drug Administr

2008

Other Studies

1 other study available for midazolam and Plasmodium falciparum Malaria

ArticleYear
Determination of midazolam and its major metabolite 1'-hydroxymidazolam by high-performance liquid chromatography-electrospray mass spectrometry in plasma from children.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Jul-05, Volume: 821, Issue:1

    Topics: Anticonvulsants; Child; Chromatography, High Pressure Liquid; Humans; Kenya; Malaria, Falciparum; Mi

2005