Page last updated: 2024-10-31

midazolam and Pain, Intractable

midazolam has been researched along with Pain, Intractable in 5 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.

Research Excerpts

ExcerptRelevanceReference
"Phantom pain is one of the most difficult intractable pains to manage."5.31Midazolam for the treatment of phantom limb pain exacerbation: preliminary reports. ( Pausawasdi, S; Vichitrananda, C, 2001)
"48 terminal cancer patients suffering from chronic pain."2.69Low doses of epidural ketamine or neostigmine, but not midazolam, improve morphine analgesia in epidural terminal cancer pain therapy. ( Gomes, JM; Lauretti, GR; Pereira, NL; Reis, MP, 1999)
" The mean dosage for midazolam was 18."1.32Use of sedation to relieve refractory symptoms in dying patients. ( Blitz-Lindeque, J; Bridge, D; Cameron, D, 2004)
"Phantom pain is one of the most difficult intractable pains to manage."1.31Midazolam for the treatment of phantom limb pain exacerbation: preliminary reports. ( Pausawasdi, S; Vichitrananda, C, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cameron, D1
Bridge, D1
Blitz-Lindeque, J1
Weber, M1
Strohscheer, I1
Samonigg, H1
Huber, C1
Lauretti, GR1
Gomes, JM1
Reis, MP1
Pereira, NL1
Vichitrananda, C1
Pausawasdi, S1
Klepstad, P1
Borchgrevink, P1
Hval, B1
Flaat, S1
Kaasa, S1

Trials

1 trial available for midazolam and Pain, Intractable

ArticleYear
Low doses of epidural ketamine or neostigmine, but not midazolam, improve morphine analgesia in epidural terminal cancer pain therapy.
    Journal of clinical anesthesia, 1999, Volume: 11, Issue:8

    Topics: Adult; Aged; Analgesia, Epidural; Double-Blind Method; Drug Synergism; Female; Humans; Ketamine; Mal

1999

Other Studies

4 other studies available for midazolam and Pain, Intractable

ArticleYear
Use of sedation to relieve refractory symptoms in dying patients.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2004, Volume: 94, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aged, 80 and over; Communication; Conscious Sedatio

2004
[Palliative sedation--an alternative to euthanasia in intractable pain at the end of life?].
    Medizinische Klinik (Munich, Germany : 1983), 2005, May-13, Volume: 100, Issue:5

    Topics: Aged; Conscious Sedation; Cross-Cultural Comparison; Ethics, Medical; Euthanasia, Active; Germany; H

2005
Midazolam for the treatment of phantom limb pain exacerbation: preliminary reports.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84, Issue:2

    Topics: Adult; Female; GABA Modulators; Humans; Male; Midazolam; Middle Aged; Pain, Intractable; Phantom Lim

2001
Long-term treatment with ketamine in a 12-year-old girl with severe neuropathic pain caused by a cervical spinal tumor.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:9

    Topics: Analgesia, Patient-Controlled; Analgesics; Brain Stem; Cervical Vertebrae; Child; Diazepam; Drug Res

2001