midazolam has been researched along with Overweight in 2 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Safe Apnea Time was defined as the time from administration of neuromuscular blocking drugs to oxygen saturation fell to 92%." | 9.15 | Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients. ( Huang, S; Li, S; Ma, H; Tang, L; Wang, Z, 2011) |
| "In view of the increasing prevalence of obesity in adolescents, the aim of this study was to determine the pharmacokinetics of the CYP3A substrate midazolam and its metabolites in overweight and obese adolescents." | 7.81 | Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents. ( Barrett, JS; Knibbe, CA; Moorthy, GS; van den Anker, JN; van Rongen, A; Vaughns, JD, 2015) |
| " Safe Apnea Time was defined as the time from administration of neuromuscular blocking drugs to oxygen saturation fell to 92%." | 5.15 | Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients. ( Huang, S; Li, S; Ma, H; Tang, L; Wang, Z, 2011) |
| "In view of the increasing prevalence of obesity in adolescents, the aim of this study was to determine the pharmacokinetics of the CYP3A substrate midazolam and its metabolites in overweight and obese adolescents." | 3.81 | Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents. ( Barrett, JS; Knibbe, CA; Moorthy, GS; van den Anker, JN; van Rongen, A; Vaughns, JD, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Rongen, A | 1 |
| Vaughns, JD | 1 |
| Moorthy, GS | 1 |
| Barrett, JS | 1 |
| Knibbe, CA | 1 |
| van den Anker, JN | 1 |
| Tang, L | 1 |
| Li, S | 1 |
| Huang, S | 1 |
| Ma, H | 1 |
| Wang, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Preoxygenation With Optiflow™, a High Flow Nasal Cannula (HFNC), is Superior to Preoxygenation With Facemask in Morbidly Obese Patients Undergoing General Anesthesia[NCT03009877] | 0 participants (Actual) | Interventional | 2018-07-31 | Withdrawn (stopped due to withdrawn prior to IRB approval) | |||
| "A Less-rapid Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the Duration of Apnea Without Desaturation in Paralyzed Non-obese and Morbidly Obese Patients?"[NCT02943629] | 0 participants (Actual) | Interventional | 2016-11-30 | Withdrawn (stopped due to Lack of feasibility) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for midazolam and Overweight
| Article | Year |
|---|---|
Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients.
Topics: Adult; Androstanols; Anesthesia, General; Apnea; Blood Gas Analysis; Body Mass Index; Endpoint Deter | 2011 |
Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients.
Topics: Adult; Androstanols; Anesthesia, General; Apnea; Blood Gas Analysis; Body Mass Index; Endpoint Deter | 2011 |
Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients.
Topics: Adult; Androstanols; Anesthesia, General; Apnea; Blood Gas Analysis; Body Mass Index; Endpoint Deter | 2011 |
Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients.
Topics: Adult; Androstanols; Anesthesia, General; Apnea; Blood Gas Analysis; Body Mass Index; Endpoint Deter | 2011 |
1 other study available for midazolam and Overweight
| Article | Year |
|---|---|
Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents.
Topics: Adolescent; Body Weight; Child; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Models, Bi | 2015 |