midazolam has been researched along with Necrosis in 7 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We present here a case of a full hand mummification and necrosis following repeated injection of chopped midazolam at the elbow, forearm and hand." | 8.12 | Hand gangrene after repetitive IV midazolam injections. ( Di Summa, PG; Haselbach, C; Sapino, G, 2022) |
| " We present here a case of a full hand mummification and necrosis following repeated injection of chopped midazolam at the elbow, forearm and hand." | 4.12 | Hand gangrene after repetitive IV midazolam injections. ( Di Summa, PG; Haselbach, C; Sapino, G, 2022) |
| "Spinally administered midazolam, even in large doses, does not cause acute neurotoxicity or inflammation of the spinal cord." | 3.70 | Acute phase histopathological study of spinally administered midazolam in cats. ( Hanaoka, K; Matsukawa, T; Nishiyama, T, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Sapino, G | 1 |
| Haselbach, C | 1 |
| Di Summa, PG | 1 |
| Zombori, L | 1 |
| Bacon, M | 1 |
| Wood, H | 1 |
| Chatterjee, F | 1 |
| Venkateswaran, R | 1 |
| Lampariello, S | 1 |
| Yoong, M | 1 |
| Ohno, S | 1 |
| Kobayashi, K | 1 |
| Uchida, S | 1 |
| Amano, O | 1 |
| Sakagami, H | 1 |
| Nagasaka, H | 1 |
| Righini, M | 1 |
| Angellillo-Scherrer, A | 1 |
| Gueddi, S | 1 |
| Le Gal, G | 1 |
| Bounameaux, H | 1 |
| Erdine, S | 1 |
| Yücel, A | 1 |
| Ozyalçin, S | 1 |
| Ozyuvaci, E | 1 |
| Talu, GK | 1 |
| Ahiskali, B | 1 |
| Apak, H | 1 |
| Savci, N | 1 |
| Nishiyama, T | 1 |
| Matsukawa, T | 1 |
| Hanaoka, K | 1 |
| Hayward, IJ | 1 |
| Wall, HG | 1 |
| Jaax, NK | 1 |
| Wade, JV | 1 |
| Marlow, DD | 1 |
| Nold, JB | 1 |
7 other studies available for midazolam and Necrosis
| Article | Year |
|---|---|
Hand gangrene after repetitive IV midazolam injections.
Topics: Adult; Gangrene; Hand; Humans; Male; Midazolam; Necrosis; Upper Extremity | 2022 |
Severe cortical damage associated with COVID-19 case report.
Topics: Acute Kidney Injury; Adolescent; Airway Extubation; Anticonvulsants; Blood Coagulation Disorders; Bo | 2021 |
Cytotoxicity and type of cell death induced by midazolam in human oral normal and tumor cells.
Topics: Anesthetics, Intravenous; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Diazepam; DNA Frag | 2012 |
Management of severe ischemia of the hand following intra-arterial injection.
Topics: Adult; Amputation, Surgical; Angiography; Fibrinolytic Agents; Fingers; Forearm; Gangrene; Hand; Hum | 2005 |
Neurotoxicity of midazolam in the rabbit.
Topics: Animals; Heart Rate; Injections, Spinal; Male; Microscopy, Electron; Midazolam; Necrosis; Nerve Dege | 1999 |
Acute phase histopathological study of spinally administered midazolam in cats.
Topics: Acute-Phase Reaction; Adjuvants, Anesthesia; Animals; Atrophy; Cats; Inflammation; Injections, Spina | 1999 |
Decreased brain pathology in organophosphate-exposed rhesus monkeys following benzodiazepine therapy.
Topics: Animals; Brain; Diazepam; Macaca mulatta; Male; Midazolam; Necrosis; Neurons; Soman | 1990 |