midazolam has been researched along with Muscle Spasticity in 6 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| " For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0." | 3.69 | Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994) |
| "After the maximal reduction of spasticity, the patients became drowsy." | 1.28 | Direct spinal effect of a benzodiazepine (midazolam) on spasticity in man. ( Beric, A; Dahm, LS; Dimitrijevic, MR; Wall, PD, 1989) |
| " Using an appropriate dosage of intrathecal midazolam selective blockade of spasticity of the hind legs may be demonstrated with integrated EMG." | 1.27 | [Spasticity treatment with spinal morphine or midazolam. In vitro experiments, animal studies and clinical studies on compatibility and effectiveness]. ( Boldt, J; Börner, U; Gerlach, H; Hempelmann, G; Hild, P; Müller, H; Oehler, KU; Zierski, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, R | 1 |
| Sneade, C | 1 |
| Littler, K | 1 |
| Ortiz-Gómez, JR | 1 |
| Souto-Ferro, JM | 1 |
| Geiduschek, JM | 1 |
| Haberkern, CM | 1 |
| McLaughlin, JF | 1 |
| Jacobson, LE | 1 |
| Hays, RM | 1 |
| Roberts, TS | 1 |
| Adachi, H | 1 |
| Riku, S | 1 |
| Fujishiro, K | 1 |
| Kuru, S | 1 |
| Dahm, LS | 1 |
| Beric, A | 1 |
| Dimitrijevic, MR | 1 |
| Wall, PD | 1 |
| Müller, H | 1 |
| Gerlach, H | 1 |
| Boldt, J | 1 |
| Börner, U | 1 |
| Hild, P | 1 |
| Oehler, KU | 1 |
| Zierski, J | 1 |
| Hempelmann, G | 1 |
1 trial available for midazolam and Muscle Spasticity
| Article | Year |
|---|---|
Effectiveness of sedation using nitrous oxide compared with enteral midazolam for botulinum toxin A injections in children.
Topics: Adolescent; Anesthetics, Inhalation; Anesthetics, Intravenous; Botulinum Toxins, Type A; Cerebral Pa | 2009 |
5 other studies available for midazolam and Muscle Spasticity
| Article | Year |
|---|---|
[Anesthesia for a patient with mitochondrial respiratory chain complex III deficiency].
Topics: Adjuvants, Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Electromyography; E | 2006 |
Pain management for children following selective dorsal rhizotomy.
Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva | 1994 |
[A case of Satoyoshi syndrome with symptoms resembling neuroleptic malignant syndrome].
Topics: Adult; Anti-Anxiety Agents; Humans; Male; Midazolam; Muscle Spasticity; Neuroleptic Malignant Syndro | 1998 |
Direct spinal effect of a benzodiazepine (midazolam) on spasticity in man.
Topics: Adult; Dose-Response Relationship, Drug; Humans; Injections, Epidural; Male; Midazolam; Muscle Spast | 1989 |
[Spasticity treatment with spinal morphine or midazolam. In vitro experiments, animal studies and clinical studies on compatibility and effectiveness].
Topics: Animals; Benzodiazepines; Cats; Drug Incompatibility; Electromyography; Epidural Space; Heart Rate; | 1986 |