midazolam has been researched along with Morphine Abuse in 5 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Coadministration of midazolam (2 mg/kg, ip) and morphine prevented the development of both acute and chronic morphine dependence in mice." | 3.71 | Pretreatment with midazolam suppresses morphine withdrawal response in mice and rats. ( Cao, JL; Ding, HL; Duan, SM; Zeng, YM; Zhang, LC, 2002) |
| "Midazolam was injected at four different concentrations: 0." | 1.29 | Inhibition of morphine-induced tolerance and dependence by a benzodiazepine receptor agonist midazolam in the rat. ( McDonald, JS; Rattan, AK; Sheu, MJ; Sribanditmongkol, P; Tejwani, GA; Zuniga, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, JL | 1 |
| Ding, HL | 1 |
| Zhang, LC | 1 |
| Duan, SM | 1 |
| Zeng, YM | 1 |
| Li, JX | 1 |
| McMahon, LR | 1 |
| Gerak, LR | 1 |
| Becker, GL | 1 |
| France, CP | 1 |
| Tejwani, GA | 1 |
| Rattan, AK | 1 |
| Sribanditmongkol, P | 1 |
| Sheu, MJ | 1 |
| Zuniga, J | 1 |
| McDonald, JS | 1 |
| Yaster, M | 1 |
| Kost-Byerly, S | 1 |
| Berde, C | 1 |
| Billet, C | 1 |
| Streel, E | 1 |
| Dan, B | 1 |
| Bredas, P | 1 |
| Clement, B | 1 |
| Pelc, I | 1 |
| Verbanck, P | 1 |
1 review available for midazolam and Morphine Abuse
| Article | Year |
|---|---|
The management of opioid and benzodiazepine dependence in infants, children, and adolescents.
Topics: Adolescent; Analgesia, Patient-Controlled; Anti-Anxiety Agents; Child; Child, Preschool; Drug Admini | 1996 |
4 other studies available for midazolam and Morphine Abuse
| Article | Year |
|---|---|
Pretreatment with midazolam suppresses morphine withdrawal response in mice and rats.
Topics: Adenosine Monophosphate; Animals; Anti-Anxiety Agents; Mice; Midazolam; Morphine Dependence; Naloxon | 2002 |
Interactions between Delta(9)-tetrahydrocannabinol and mu opioid receptor agonists in rhesus monkeys: discrimination and antinociception.
Topics: Analgesics; Analgesics, Opioid; Animals; Data Interpretation, Statistical; Discrimination, Psycholog | 2008 |
Inhibition of morphine-induced tolerance and dependence by a benzodiazepine receptor agonist midazolam in the rat.
Topics: Animals; Drug Tolerance; Male; Midazolam; Morphine; Morphine Dependence; Pain; Rats; Rats, Sprague-D | 1993 |
Interference with withdrawal signs of naloxone-induced opiate withdrawal under anesthesia is anesthetic-specific in opiate-dependent rats.
Topics: Anesthesia, General; Anesthetics, Dissociative; Animals; Defecation; Dose-Response Relationship, Dru | 2001 |