midazolam has been researched along with Liver Diseases in 9 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The elimination half-life of midazolam was about 3 times longer in hepatectomy group (24." | 1.29 | [Pharmacokinetics of midazolam in patients with liver damage for hepatectomy]. ( Hirasaki, A; Iwasaki, T; Konishi, H; Nishiyama, T; Seto, K; Toda, N, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Fung, BM | 1 |
| Leon, DJ | 1 |
| Beck, LN | 1 |
| Tabibian, JH | 1 |
| Sornsakrin, M | 1 |
| Helmke, K | 1 |
| Briem-Richter, A | 1 |
| Ganschow, R | 1 |
| Djurberg, H | 1 |
| Pothmann Facharzt, W | 1 |
| Joseph, D | 1 |
| Tjan, D | 1 |
| Zuleika, M | 1 |
| Ferns, S | 1 |
| Rasheed, A | 1 |
| Evans, DA | 1 |
| Bassas, A | 1 |
| Abdallah, H | 1 |
| Jerling, M | 1 |
| Nishiyama, T | 1 |
| Hirasaki, A | 1 |
| Toda, N | 1 |
| Iwasaki, T | 1 |
| Konishi, H | 1 |
| Seto, K | 1 |
| Park, GR | 1 |
| Miller, E | 1 |
| Hashida, K | 1 |
| Taniguchi, K | 1 |
| Miyakawa, H | 1 |
| Miyamoto, M | 1 |
| Oda, S | 1 |
| Honda, N | 1 |
| Woonton, B | 1 |
| Brouillette, DE | 1 |
| Yoo, YK | 1 |
| Chien, MC | 1 |
| Rabinovitz, M | 1 |
| Tarter, RE | 1 |
| Van Thiel, DH | 1 |
1 review available for midazolam and Liver Diseases
| Article | Year |
|---|---|
Pre-procedural Preparation and Sedation for Gastrointestinal Endoscopy in Patients with Advanced Liver Disease.
Topics: Conscious Sedation; Endoscopy, Gastrointestinal; Fentanyl; Humans; Hypnotics and Sedatives; Liver Di | 2022 |
2 trials available for midazolam and Liver Diseases
| Article | Year |
|---|---|
Effect of hepatic impairment on the multiple-dose pharmacokinetics of ranolazine sustained-release tablets.
Topics: Acetanilides; Area Under Curve; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Delayed-Acti | 2005 |
Use of midazolam for percutaneous liver biopsy.
Topics: Adult; Aged; Biopsy, Needle; Humans; Liver Diseases; Memory; Midazolam; Middle Aged; Patient Complia | 1989 |
6 other studies available for midazolam and Liver Diseases
| Article | Year |
|---|---|
Value of ultrasound-guided percutaneous liver biopsy in children following liver transplantation.
Topics: Adolescent; Biopsy, Needle; Child; Child, Preschool; Female; Humans; Incidence; Infant; Ketamine; Li | 2010 |
Anesthesia care for living-related liver transplantation for infants and children with end-stage liver disease: report of our initial experience.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Intravenous; Atracurium; Biliary Atresia; Child; Child, Pr | 2002 |
[Pharmacokinetics of midazolam in patients with liver damage for hepatectomy].
Topics: Aged; Female; Gastrectomy; Hepatectomy; Humans; Liver Diseases; Male; Midazolam; Middle Aged | 1993 |
What changes drug metabolism in critically ill patients--III? Effect of pre-existing disease on the metabolism of midazolam.
Topics: Adult; Biotransformation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Graft Rejection; | 1996 |
[Clinical evaluation of midazolam as an anesthetic for geriatric patients and patients with hepatic dysfunction].
Topics: Adult; Aged; Anesthetics; Female; Geriatrics; Humans; Injections, Intravenous; Liver Diseases; Male; | 1990 |
Midazolam.
Topics: Analgesia; Humans; Liver; Liver Diseases; Midazolam | 1990 |