midazolam has been researched along with Leukemia in 3 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This retrospective study compared the use of thiamylal plus pentazocine (TP) to ketamine plus midazolam (KM) in children with leukemia who were undergoing bone marrow aspiration and/or intrathecal chemotherapy." | 7.88 | Thiamylal Plus Pentazocine Shows Similar Efficacy as Ketamine Plus Midazolam for Painful Procedures in Children With Leukemia. ( Kawano, Y; Kodama, Y; Nakagawa, S; Nishikawa, T; Okamoto, Y; Tanabe, T, 2018) |
| "The pain and distress ratings of patients undergoing BMAs (n = 73) and LPs (n = 105) were examined in a comparison of 3 different interventions: (1) a topical eutectic mixture of lidocaine and prilocaine (EMLA cream), (2) oral midazolam and EMLA cream, or (3) propofol/fentanyl general anesthesia." | 5.10 | Pain and distress from bone marrow aspirations and lumbar punctures. ( Doran, NH; Frost, JD; Holdsworth, MT; Mathew, P; Moro, MA; Pankey, JM; Phillips, J; Raisch, DW; Winter, SS, 2003) |
| "This retrospective study compared the use of thiamylal plus pentazocine (TP) to ketamine plus midazolam (KM) in children with leukemia who were undergoing bone marrow aspiration and/or intrathecal chemotherapy." | 3.88 | Thiamylal Plus Pentazocine Shows Similar Efficacy as Ketamine Plus Midazolam for Painful Procedures in Children With Leukemia. ( Kawano, Y; Kodama, Y; Nakagawa, S; Nishikawa, T; Okamoto, Y; Tanabe, T, 2018) |
| "Children with leukemia have to undergo many times painful procedures like bone-marrow aspiration and lumbar puncture." | 1.27 | [Sedation and analgesia in interventions]. ( de Waal, FC; Huisman, J; Veerman, AJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakagawa, S | 1 |
| Okamoto, Y | 1 |
| Kodama, Y | 1 |
| Nishikawa, T | 1 |
| Tanabe, T | 1 |
| Kawano, Y | 1 |
| Holdsworth, MT | 1 |
| Raisch, DW | 1 |
| Winter, SS | 1 |
| Frost, JD | 1 |
| Moro, MA | 1 |
| Doran, NH | 1 |
| Phillips, J | 1 |
| Pankey, JM | 1 |
| Mathew, P | 1 |
| de Waal, FC | 1 |
| Huisman, J | 1 |
| Veerman, AJ | 1 |
1 trial available for midazolam and Leukemia
| Article | Year |
|---|---|
Pain and distress from bone marrow aspirations and lumbar punctures.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Biopsy, Needle; Bon | 2003 |
2 other studies available for midazolam and Leukemia
| Article | Year |
|---|---|
Thiamylal Plus Pentazocine Shows Similar Efficacy as Ketamine Plus Midazolam for Painful Procedures in Children With Leukemia.
Topics: Child; Child, Preschool; Deep Sedation; Female; Humans; Infant; Ketamine; Leukemia; Male; Midazolam; | 2018 |
[Sedation and analgesia in interventions].
Topics: Analgesics; Anesthesia; Child; Child, Preschool; Humans; Leukemia; Midazolam; Pain; Premedication | 1988 |