midazolam has been researched along with Left Ventricular Dysfunction in 5 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The MIMO trial randomized 111 patients with acute pulmonary edema to receive intravenous midazolam in 1-mg doses to a maximum of 3 mg (n = 55) or morphine in 2- to 4-mg doses to a maximum of 8 mg (n= 56)." | 9.69 | Effects of midazolam vs morphine in patients with acute pulmonary edema with left ventricular systolic dysfunction: a secondary analysis of data from the MIMO trial. ( Abreu-González, P; Burillo-Putze, G; Calvo-Rodríguez, R; Domínguez-Rodríguez, A; Formica, F; Gil, V; Hernández-Vaquero, D; Llorens, P; Martín-Sánchez, FJ; Miró, Ò; Piñera-Salmerón, P; Suero-Méndez, C, 2023) |
| "The MIMO trial randomized 111 patients with acute pulmonary edema to receive intravenous midazolam in 1-mg doses to a maximum of 3 mg (n = 55) or morphine in 2- to 4-mg doses to a maximum of 8 mg (n= 56)." | 5.69 | Effects of midazolam vs morphine in patients with acute pulmonary edema with left ventricular systolic dysfunction: a secondary analysis of data from the MIMO trial. ( Abreu-González, P; Burillo-Putze, G; Calvo-Rodríguez, R; Domínguez-Rodríguez, A; Formica, F; Gil, V; Hernández-Vaquero, D; Llorens, P; Martín-Sánchez, FJ; Miró, Ò; Piñera-Salmerón, P; Suero-Méndez, C, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Domínguez-Rodríguez, A | 1 |
| Hernández-Vaquero, D | 1 |
| Suero-Méndez, C | 1 |
| Burillo-Putze, G | 1 |
| Gil, V | 1 |
| Calvo-Rodríguez, R | 1 |
| Piñera-Salmerón, P | 1 |
| Llorens, P | 1 |
| Martín-Sánchez, FJ | 1 |
| Abreu-González, P | 1 |
| Formica, F | 1 |
| Miró, Ò | 1 |
| Couture, P | 1 |
| Denault, AY | 1 |
| Shi, Y | 1 |
| Deschamps, A | 1 |
| Cossette, M | 1 |
| Pellerin, M | 1 |
| Tardif, JC | 1 |
| Neuhäuser, C | 1 |
| Müller, M | 1 |
| Welters, I | 1 |
| Scholz, S | 1 |
| Kwapisz, MM | 1 |
| Kleinschmidt, S | 1 |
| Grueness, V | 1 |
| Molter, G | 1 |
| Gare, M | 1 |
| Parail, A | 1 |
| Milosavljevic, D | 1 |
| Kersten, JR | 1 |
| Warltier, DC | 1 |
| Pagel, PS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Remifentanil on Diastolic and Systolic Function in Patients With Diastolic Dysfunction[NCT04117009] | Phase 4 | 30 participants (Anticipated) | Interventional | 2019-11-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for midazolam and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Effects of midazolam vs morphine in patients with acute pulmonary edema with left ventricular systolic dysfunction: a secondary analysis of data from the MIMO trial.
Topics: Humans; Midazolam; Morphine; Pulmonary Edema; Stroke Volume; Ventricular Dysfunction, Left; Ventricu | 2023 |
Effect of isoflurane on echocardiographic left-ventricular relaxation indices in patients with diastolic dysfunction due to concentric hypertrophy and ischemic heart disease.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents; Cardiovascular Phy | 2006 |
Conscious sedation with midazolam or propofol does not alter left ventricular diastolic performance in patients with preexisting diastolic dysfunction: a transmitral and tissue Doppler transthoracic echocardiography study.
Topics: Adult; Diastole; Double-Blind Method; Echocardiography; Female; Heart Rate; Hemodynamics; Humans; Hy | 2001 |
2 other studies available for midazolam and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Effects of anesthetic induction in patients with diastolic dysfunction.
Topics: Aged; Anesthesia, General; Anesthetics, General; Blood Flow Velocity; Blood Pressure; Coronary Arter | 2009 |
The Bland-White-Garland syndrome. Clinical picture and anaesthesiological management.
Topics: Adrenergic alpha-Agonists; Anesthesia, Intravenous; Anesthetics, Intravenous; Aorta; Cardiopulmonary | 1996 |