midazolam has been researched along with Intraocular Pressure in 21 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effect of propofol, alfaxalone and ketamine on intraocular pressure (IOP) in cats." | 9.69 | Effect of anesthetic induction with propofol, alfaxalone or ketamine on intraocular pressure in cats: a randomized masked clinical investigation. ( Abu Ahmad, W; Ofri, R; Pe'er, O; Shilo-Benjamini, Y, 2023) |
| "To determine the effects of intravenous ketamine-midazolam anesthesia on intraocular pressure (IOP) in ocular normotensive dogs." | 9.14 | The effects of ketamine-midazolam anesthesia on intraocular pressure in clinically normal dogs. ( Ghaffari, MS; Khorami, N; Mirani, AH; Rezaei, MA, 2010) |
| "The effect of midazolam on intraocular pressure (IOP) in adults was studied as an initial step in determining whether it can be used as a preoperative anxiolytic or sedative agent in children with glaucoma who are undergoing examination for IOP measurements." | 9.09 | A randomized trial of the effect of midazolam on intraocular pressure. ( Berman, LS; Carter, K; Faberowski, LK; McGorray, S; Sherwood, MB, 1999) |
| "A programmed study on the effect of sodium thiopentone and midazolam on systemic blood pressure, pulse rate and intraocular pressure was done on sixty patients." | 9.06 | Effect of sodium thiopentone and midazolam on intraocular pressure, pulse rate and blood pressure--a comparative study. ( Badran, I; Farah, I; Ukra, HS, 1988) |
| "The effect on intraocular pressure of induction of anesthesia with 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazol[1,5-a][1,4]benzodiazepine (midazolam, Ro 21-3981, Dormicum) as maleate or 7-chloro-1,3-dihydro-1-methyl-5-phenyl-(2H)-1,4-benzodiazepin-2-one (diazepam) has not previously been reported." | 9.05 | The effect of midazolam maleate and diazepam on intraocular pressure in adults. ( Fragen, RJ; Hauch, T, 1981) |
| "This article describes the development of decreased intraocular pressure (IOP) under general anesthesia with medetomidine, midazolam, and fentanyl in mice with normal and elevated IOP." | 8.12 | Changes in Intraocular Pressure following Narcosis With Medetomidine, Midazolam, and Fentanyl in Association With Initial Intraocular Pressure in Mice. ( Binter, M; Framme, C; Heider, M; Langer, F; Lüdtke, P; Schigiel, T; Tode, J, 2022) |
| "To evaluate selected effects of midazolam or lidocaine administered prior to etomidate for co-induction of anesthesia in healthy dogs." | 7.96 | The effect of midazolam or lidocaine administration prior to etomidate induction of anesthesia on heart rate, arterial pressure, intraocular pressure and serum cortisol concentration in healthy dogs. ( Ambrisko, TD; Carroll, MQ; Keating, SC; Martins, B; Oba, PM; Sage, AM; Somrak, A; Swanson, KS, 2020) |
| "To compare the effect of propofol, alfaxalone and ketamine on intraocular pressure (IOP) in cats." | 5.69 | Effect of anesthetic induction with propofol, alfaxalone or ketamine on intraocular pressure in cats: a randomized masked clinical investigation. ( Abu Ahmad, W; Ofri, R; Pe'er, O; Shilo-Benjamini, Y, 2023) |
| "Flumazenil was given at 45 and 90 min as in Group 2." | 5.28 | Intraocular pressure in anaesthetized dogs given flumazenil with and without prior administration of midazolam. ( Artru, AA, 1991) |
| "A programmed study on the effect of sodium thiopentone and midazolam on systemic blood pressure, pulse rate and intraocular pressure was done on sixty patients." | 5.06 | Effect of sodium thiopentone and midazolam on intraocular pressure, pulse rate and blood pressure--a comparative study. ( Badran, I; Farah, I; Ukra, HS, 1988) |
| "The effect on intraocular pressure of induction of anesthesia with 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazol[1,5-a][1,4]benzodiazepine (midazolam, Ro 21-3981, Dormicum) as maleate or 7-chloro-1,3-dihydro-1-methyl-5-phenyl-(2H)-1,4-benzodiazepin-2-one (diazepam) has not previously been reported." | 5.05 | The effect of midazolam maleate and diazepam on intraocular pressure in adults. ( Fragen, RJ; Hauch, T, 1981) |
| "This article describes the development of decreased intraocular pressure (IOP) under general anesthesia with medetomidine, midazolam, and fentanyl in mice with normal and elevated IOP." | 4.12 | Changes in Intraocular Pressure following Narcosis With Medetomidine, Midazolam, and Fentanyl in Association With Initial Intraocular Pressure in Mice. ( Binter, M; Framme, C; Heider, M; Langer, F; Lüdtke, P; Schigiel, T; Tode, J, 2022) |
| "To compare effects of anesthetic induction with midazolam-propofol or midazolam-etomidate on intraocular pressure (IOP), pupillary diameter (PD), pulse rate, blood pressure, and respiratory rate in clinically normal dogs." | 3.79 | Effects of anesthetic induction with midazolam-propofol and midazolam-etomidate on selected ocular and cardiorespiratory variables in clinically normal dogs. ( Ashton, MM; Gunderson, EG; Lukasik, VM; Madsen, R; Merideth, RE, 2013) |
| "Intraocular pressure was measured by rebound tonometry." | 1.51 | Effects of injectable dexmedetomidine-ketamine-midazolam and isoflurane inhalation anesthetic protocols on ocular variables in captive black-tailed prairie dogs ( ( Beaufrère, H; Browning, GR; Eshar, D; Meekins, JM; Roberts, JK, 2019) |
| "Flumazenil was given at 45 and 90 min as in Group 2." | 1.28 | Intraocular pressure in anaesthetized dogs given flumazenil with and without prior administration of midazolam. ( Artru, AA, 1991) |
| "A new water-soluble benzodiazepine, midazolam maleate, was used at a dosage of 0." | 1.27 | [Midazolam as an induction agent for surgery of the anterior segment of the eye]. ( Basili, P; Gasparetto, A; Pinto, G; Silvi, MB, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 5 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Bayraktaroglu, M | 1 |
| Kurtay, A | 1 |
| Horasanli, E | 1 |
| Binter, M | 1 |
| Lüdtke, P | 1 |
| Langer, F | 1 |
| Schigiel, T | 1 |
| Framme, C | 1 |
| Heider, M | 1 |
| Tode, J | 1 |
| Shilo-Benjamini, Y | 2 |
| Pe'er, O | 2 |
| Abu Ahmad, W | 2 |
| Ofri, R | 2 |
| Roberts, JK | 1 |
| Meekins, JM | 1 |
| Browning, GR | 1 |
| Beaufrère, H | 1 |
| Eshar, D | 1 |
| Keating, SC | 1 |
| Sage, AM | 1 |
| Ambrisko, TD | 1 |
| Somrak, A | 1 |
| Carroll, MQ | 1 |
| Oba, PM | 1 |
| Martins, B | 1 |
| Swanson, KS | 1 |
| Dhingra, D | 1 |
| Ghai, B | 1 |
| Sabharwal, P | 1 |
| Saini, V | 1 |
| Snehi, S | 1 |
| Kaur, M | 1 |
| Pandav, SS | 1 |
| Kaushik, S | 1 |
| Gunderson, EG | 1 |
| Lukasik, VM | 1 |
| Ashton, MM | 1 |
| Merideth, RE | 1 |
| Madsen, R | 1 |
| Kavitha, J | 1 |
| Parida, S | 1 |
| Kundra, P | 1 |
| Srinivasan, R | 1 |
| Mayordomo-Febrer, A | 1 |
| Rubio, M | 1 |
| Martínez-Gassent, M | 1 |
| López-Murcia, MM | 1 |
| Ghaffari, MS | 1 |
| Rezaei, MA | 1 |
| Mirani, AH | 1 |
| Khorami, N | 1 |
| Oberacher-Velten, I | 1 |
| Prasser, C | 1 |
| Rochon, J | 1 |
| Ittner, KP | 1 |
| Helbig, H | 1 |
| Lorenz, B | 1 |
| Pinto, G | 1 |
| Silvi, MB | 1 |
| Basili, P | 1 |
| Gasparetto, A | 1 |
| Fragen, RJ | 1 |
| Hauch, T | 1 |
| Virkkilä, M | 1 |
| Ali-Melkkilä, T | 1 |
| Kanto, J | 1 |
| Turunen, J | 1 |
| Scheinin, H | 1 |
| Kubo, N | 1 |
| Sakuragi, T | 1 |
| Mayama, T | 1 |
| Shinokuma, T | 1 |
| Horie, T | 1 |
| Dan, K | 1 |
| Carter, K | 1 |
| Faberowski, LK | 1 |
| Sherwood, MB | 1 |
| Berman, LS | 1 |
| McGorray, S | 1 |
| Artru, AA | 1 |
| Gobeaux, D | 1 |
| Sardnal, F | 1 |
| Ukra, HS | 1 |
| Badran, I | 2 |
| Farah, I | 2 |
| Ukra, H | 1 |
| Hirlinger, WK | 1 |
| Wick, C | 1 |
| Stodtmeister, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Dexmedetomidine and Midazolam as Intramuscular Premedication for Suspension Laryngoscopy[NCT01937611] | Phase 4 | 40 participants (Anticipated) | Interventional | 2013-03-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 trials available for midazolam and Intraocular Pressure
| Article | Year |
|---|---|
Comparison of two sedation protocols on intraocular pressure and hemodynamic responses during colonoscopy.
Topics: Adult; Aged; Colonoscopy; Eye Diseases; Hemodynamics; Humans; Hypnotics and Sedatives; Intraocular P | 2022 |
Effect of anesthetic induction with propofol, alfaxalone or ketamine on intraocular pressure in cats: a randomized masked clinical investigation.
Topics: Anesthetics; Animals; Cats; Intraocular Pressure; Ketamine; Midazolam; Pregnanediones; Propofol; Pro | 2023 |
Effect of anesthetic induction with propofol, alfaxalone or ketamine on intraocular pressure in cats: a randomized masked clinical investigation.
Topics: Anesthetics; Animals; Cats; Intraocular Pressure; Ketamine; Midazolam; Pregnanediones; Propofol; Pro | 2023 |
Effect of anesthetic induction with propofol, alfaxalone or ketamine on intraocular pressure in cats: a randomized masked clinical investigation.
Topics: Anesthetics; Animals; Cats; Intraocular Pressure; Ketamine; Midazolam; Pregnanediones; Propofol; Pro | 2023 |
Effect of anesthetic induction with propofol, alfaxalone or ketamine on intraocular pressure in cats: a randomized masked clinical investigation.
Topics: Anesthetics; Animals; Cats; Intraocular Pressure; Ketamine; Midazolam; Pregnanediones; Propofol; Pro | 2023 |
Evaluation of Intranasal Dexmedetomidine as a Procedural Sedative for Ophthalmic Examination of Children With Glaucoma.
Topics: Administration, Intranasal; Adrenergic alpha-2 Receptor Agonists; Anesthesia, General; Child; Child, | 2020 |
Oral gabapentin premedication for elderly patients undergoing intraocular surgery.
Topics: Administration, Oral; Amines; Analgesics; Anesthesia, Conduction; Anti-Anxiety Agents; Blood Pressur | 2013 |
The effects of ketamine-midazolam anesthesia on intraocular pressure in clinically normal dogs.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Dogs; Intraocular Pressure; Ketamine; | 2010 |
The effects of midazolam on intraocular pressure in children during examination under sedation.
Topics: Administration, Oral; Child; Child Behavior; Child, Preschool; Conscious Sedation; Female; Glaucoma; | 2011 |
The effect of midazolam maleate and diazepam on intraocular pressure in adults.
Topics: Adult; Anesthetics; Benzodiazepines; Blood Pressure; Diazepam; Heart Rate; Humans; Intraocular Press | 1981 |
Dexmedetomidine as intramuscular premedication for day-case cataract surgery. A comparative study of dexmedetomidine, midazolam and placebo.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Blood Pre | 1994 |
A randomized trial of the effect of midazolam on intraocular pressure.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Anti-Anxiety Agents; Double-Blind Method; Female; | 1999 |
Midazolam and flumazenil in ophthalmology.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Cornea; Double-Blind Method; Female; Flumazenil; Human | 1990 |
Effect of sodium thiopentone and midazolam on intraocular pressure, pulse rate and blood pressure--a comparative study.
Topics: Adult; Blood Pressure; Humans; Intraocular Pressure; Midazolam; Prospective Studies; Pulse; Random A | 1988 |
[Comparative study of the behavior of intraocular pressure in anesthesia induction by diazepam and midazolam].
Topics: Cataract Extraction; Clinical Trials as Topic; Diazepam; Fentanyl; Humans; Intraocular Pressure; Mid | 1986 |
9 other studies available for midazolam and Intraocular Pressure
| Article | Year |
|---|---|
Changes in Intraocular Pressure following Narcosis With Medetomidine, Midazolam, and Fentanyl in Association With Initial Intraocular Pressure in Mice.
Topics: Acetates; Animals; Dexamethasone; Female; Fentanyl; Glaucoma; Intraocular Pressure; Male; Medetomidi | 2022 |
Effects of injectable dexmedetomidine-ketamine-midazolam and isoflurane inhalation anesthetic protocols on ocular variables in captive black-tailed prairie dogs (
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Animals, Zoo; Dexmedetomidin | 2019 |
The effect of midazolam or lidocaine administration prior to etomidate induction of anesthesia on heart rate, arterial pressure, intraocular pressure and serum cortisol concentration in healthy dogs.
Topics: Anesthesia; Anesthetics, Local; Animals; Blood Pressure; Dogs; Drug Interactions; Drug Therapy, Comb | 2020 |
Effects of anesthetic induction with midazolam-propofol and midazolam-etomidate on selected ocular and cardiorespiratory variables in clinically normal dogs.
Topics: Anesthetics, Intravenous; Animals; Dogs; Drug Therapy, Combination; Etomidate; Intraocular Pressure; | 2013 |
Effects of morphine-alfaxalone-midazolam premedication, alfaxalone induction and sevoflurane maintenance on intraocular pressure and tear production in dogs.
Topics: Anesthetics; Animals; Dogs; Drug Combinations; Female; Intraocular Pressure; Methyl Ethers; Midazola | 2017 |
[Midazolam as an induction agent for surgery of the anterior segment of the eye].
Topics: Aged; Anesthesia, General; Anesthetics; Anterior Eye Segment; Benzodiazepines; Blood Gas Analysis; E | 1984 |
Collapsed anterior chamber during hypothermic cardiopulmonary bypass.
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anterior Chamber; Aqueous Humor; Cardiopulm | 1998 |
Intraocular pressure in anaesthetized dogs given flumazenil with and without prior administration of midazolam.
Topics: Anesthesia, Inhalation; Animals; Aqueous Humor; Blood Pressure; Dogs; Flumazenil; Injections, Intrav | 1991 |
The effect of midazolam and succinylcholine on systemic blood pressure and intraocular pressure.
Topics: Adolescent; Adult; Blood Pressure; Child; Female; Humans; Intraocular Pressure; Male; Midazolam; Mid | 1988 |