midazolam has been researched along with Intracranial Hypertension in 6 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Intracranial Hypertension: Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketamine has traditionally been avoided as an induction agent for tracheal intubation in patients with neurologic conditions at risk for intracranial hypertension due to conflicting data in the literature." | 8.31 | Co-administration of Ketamine in Pediatric Patients with Neurologic Conditions at Risk for Intracranial Hypertension. ( Ampah, SB; Beaulieu, F; Francoeur, C; Gajjar, AA; Griffis, H; Heuer, GG; Huh, JW; Kilbaugh, TJ; Kirschen, MP; Lang, SS; Mazandi, VM; Nishisaki, A; Rahman, RK; Storm, PB; Topjian, AA; Tucker, AM; Yuan, I; Zhang, B, 2023) |
| "To evaluate the clinical effectiveness of bolus-dose fentanyl and midazolam to treat episodic intracranial hypertension in children with severe traumatic brain injury." | 7.83 | Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury. ( Doctor, A; Kharasch, ED; Leonard, JR; Pineda, JA; Wallendorf, MJ; Welch, TP, 2016) |
| "Ketamine has traditionally been avoided as an induction agent for tracheal intubation in patients with neurologic conditions at risk for intracranial hypertension due to conflicting data in the literature." | 4.31 | Co-administration of Ketamine in Pediatric Patients with Neurologic Conditions at Risk for Intracranial Hypertension. ( Ampah, SB; Beaulieu, F; Francoeur, C; Gajjar, AA; Griffis, H; Heuer, GG; Huh, JW; Kilbaugh, TJ; Kirschen, MP; Lang, SS; Mazandi, VM; Nishisaki, A; Rahman, RK; Storm, PB; Topjian, AA; Tucker, AM; Yuan, I; Zhang, B, 2023) |
| "To evaluate the clinical effectiveness of bolus-dose fentanyl and midazolam to treat episodic intracranial hypertension in children with severe traumatic brain injury." | 3.83 | Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury. ( Doctor, A; Kharasch, ED; Leonard, JR; Pineda, JA; Wallendorf, MJ; Welch, TP, 2016) |
| "Ketamine has a long history of use during pediatric procedural sedation." | 2.78 | Pretreatment with midazolam blunts the rise in intracranial pressure associated with ketamine sedation for lumbar puncture in children. ( Berkenbosch, JW; Michalczyk, K; Sullivan, JE, 2013) |
| "The propofol infusion rate was non-significantly lower with drainage." | 1.38 | Effect of continuous cerebrospinal fluid drainage on therapeutic intensity in severe traumatic brain injury. ( Boch, AL; Boroli, F; Chauvet, D; Lescot, T; Puybasset, L; Reina, V, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Mazandi, VM | 1 |
| Lang, SS | 1 |
| Rahman, RK | 1 |
| Nishisaki, A | 1 |
| Beaulieu, F | 1 |
| Zhang, B | 1 |
| Griffis, H | 1 |
| Tucker, AM | 1 |
| Storm, PB | 1 |
| Heuer, GG | 1 |
| Gajjar, AA | 1 |
| Ampah, SB | 1 |
| Kirschen, MP | 1 |
| Topjian, AA | 1 |
| Yuan, I | 1 |
| Francoeur, C | 1 |
| Kilbaugh, TJ | 1 |
| Huh, JW | 1 |
| Welch, TP | 1 |
| Wallendorf, MJ | 1 |
| Kharasch, ED | 1 |
| Leonard, JR | 1 |
| Doctor, A | 1 |
| Pineda, JA | 1 |
| van Alfen-van der Velden, AA | 1 |
| Claessen, VP | 1 |
| Hopman, JC | 1 |
| Klaessens, JH | 1 |
| Sengers, RC | 1 |
| Liem, KD | 1 |
| Baidya, DK | 1 |
| Trikha, A | 1 |
| Menon, S | 1 |
| Garg, R | 1 |
| Lescot, T | 1 |
| Boroli, F | 1 |
| Reina, V | 1 |
| Chauvet, D | 1 |
| Boch, AL | 1 |
| Puybasset, L | 1 |
| Michalczyk, K | 1 |
| Sullivan, JE | 1 |
| Berkenbosch, JW | 1 |
1 trial available for midazolam and Intracranial Hypertension
| Article | Year |
|---|---|
Pretreatment with midazolam blunts the rise in intracranial pressure associated with ketamine sedation for lumbar puncture in children.
Topics: Adolescent; Anesthetics, Dissociative; Child; Child, Preschool; Drug Administration Schedule; Female | 2013 |
5 other studies available for midazolam and Intracranial Hypertension
| Article | Year |
|---|---|
Co-administration of Ketamine in Pediatric Patients with Neurologic Conditions at Risk for Intracranial Hypertension.
Topics: Analgesics; Child; Fentanyl; Humans; Intracranial Hypertension; Ketamine; Midazolam | 2023 |
Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury.
Topics: Adolescent; Brain Injuries; Cerebrovascular Circulation; Child; Child, Preschool; Drug Administratio | 2016 |
Changes in cerebral oxygenation and hemodynamics during cranial ultrasound in preterm infants.
Topics: Aging; Analgesics, Opioid; Biomarkers; Brain; Cerebrovascular Circulation; Cranial Fontanelles; Echo | 2009 |
Anaesthetic management of emergency caesarean section in a patient with seizures and likely raised intracranial pressure due to tuberculous meningitis.
Topics: Adult; Androstanols; Anesthesia, Obstetrical; Anesthetics, Inhalation; Anesthetics, Intravenous; Ant | 2011 |
Effect of continuous cerebrospinal fluid drainage on therapeutic intensity in severe traumatic brain injury.
Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Brain Injuries; Central Nervous System Infections; Cere | 2012 |