midazolam has been researched along with Injury, Myocardial Reperfusion in 7 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arrhythmias, Cardiac ischemia, Cardiovascular toxicity, Propofol." | 3.88 | Propofol: a safe anaesthetic drug in experimental cardiac surgery in rabbits. ( Barbieri, A; Farinetti, A; Giuliani, E; Manenti, A; Mattioli, AV, 2018) |
| "Midazolam is a benzodiazepine commonly utilized in anesthesia and intensive care." | 1.72 | Midazolam suppresses ischemia/reperfusion-induced cardiomyocyte apoptosis by inhibiting the JNK/p38 MAPK signaling pathway. ( Cai, D; Zhou, W, 2022) |
| "Midazolam is a frequently used benzodiazepine in anaesthesiology and intensive care." | 1.35 | Changes in biomechanical parameters during heart perfusion and after midazolam pre-medication--experimental pilot study. ( Bartosik, T; Bartosikova, L; Frana, P; Necas, J; Pavlik, M, 2008) |
| "With midazolam, however, the increase was comparable to that of the control group." | 1.33 | Flumazenil mimics whereas midazolam abolishes ischemic preconditioning in a rabbit heart model of ischemia-reperfusion. ( Berenshtein, E; Chevion, M; Drenger, B; Gozal, Y; Raphael, J; Rivo, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, W | 1 |
| Cai, D | 1 |
| Lassen, TR | 1 |
| Hjortbak, MV | 1 |
| Hauerslev, M | 1 |
| Tonnesen, PT | 1 |
| Kristiansen, SB | 1 |
| Jensen, RV | 1 |
| Bøtker, HE | 1 |
| Giuliani, E | 1 |
| Manenti, A | 1 |
| Barbieri, A | 1 |
| Farinetti, A | 1 |
| Mattioli, AV | 1 |
| Bettex, DA | 1 |
| Wanner, PM | 1 |
| Bosshart, M | 1 |
| Balmer, C | 1 |
| Knirsch, W | 1 |
| Dave, H | 1 |
| Dillier, C | 1 |
| Bürki, C | 1 |
| Hug, M | 1 |
| Seifert, B | 1 |
| Spahn, DR | 1 |
| Beck-Schimmer, B | 1 |
| Bartosikova, L | 1 |
| Necas, J | 1 |
| Bartosik, T | 1 |
| Frana, P | 1 |
| Pavlik, M | 1 |
| Rivo, J | 1 |
| Raphael, J | 1 |
| Drenger, B | 1 |
| Berenshtein, E | 1 |
| Chevion, M | 1 |
| Gozal, Y | 1 |
| Süzer, O | 1 |
| Köseoğlu, S | 1 |
| Senses, V | 1 |
1 trial available for midazolam and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Role of sevoflurane in organ protection during cardiac surgery in children: a randomized controlled trial.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Biomarkers; Cardiac Surgical Procedures; Cardiopu | 2015 |
6 other studies available for midazolam and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Midazolam suppresses ischemia/reperfusion-induced cardiomyocyte apoptosis by inhibiting the JNK/p38 MAPK signaling pathway.
Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; JNK Mitogen-Activated Protein Kinases; | 2022 |
Influence of strain, age, origin, and anesthesia on the cardioprotective efficacy by local and remote ischemic conditioning in an ex vivo rat model.
Topics: Analgesia; Animals; Barbiturates; Butyrophenones; Drug Combinations; Fentanyl; Hypnotics and Sedativ | 2021 |
Propofol: a safe anaesthetic drug in experimental cardiac surgery in rabbits.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Ar | 2018 |
Changes in biomechanical parameters during heart perfusion and after midazolam pre-medication--experimental pilot study.
Topics: Animals; Hypnotics and Sedatives; In Vitro Techniques; Male; Midazolam; Myocardial Contraction; Myoc | 2008 |
Flumazenil mimics whereas midazolam abolishes ischemic preconditioning in a rabbit heart model of ischemia-reperfusion.
Topics: Animals; Disease Models, Animal; Flumazenil; Heart Rate; Ischemic Preconditioning, Myocardial; Midaz | 2006 |
Midazolam is a safe agent by comparison with thiopentone on arrhythmias in ischaemia and reperfusion conditions in isolated perfused rat hearts.
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Female; Heart; In Vi | 1998 |