midazolam has been researched along with Infections, Plasmodium in 4 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe the first systematic study of antimalarial 1,2,4-trioxolanes bearing a substitution pattern regioisomeric to that of arterolane." | 7.85 | Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane. ( Blank, BR; Gut, J; Renslo, AR; Rosenthal, PJ, 2017) |
| "We describe the first systematic study of antimalarial 1,2,4-trioxolanes bearing a substitution pattern regioisomeric to that of arterolane." | 3.85 | Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane. ( Blank, BR; Gut, J; Renslo, AR; Rosenthal, PJ, 2017) |
| "In a previous study, the efficacy and safety of buccal midazolam was compared to that of rectal diazepam in the treatment of prolonged seizures in children aged three months to 12 years in Kampala, Uganda." | 3.75 | Predictors of anti-convulsant treatment failure in children presenting with malaria and prolonged seizures in Kampala, Uganda. ( Byarugaba, J; Mpimbaza, A; Ndeezi, G; Rosenthal, PJ; Staedke, SG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, K | 1 |
| Okombo, J | 2 |
| Brunschwig, C | 1 |
| Ndubi, F | 1 |
| Barnard, L | 1 |
| Wilkinson, C | 1 |
| Njogu, PM | 1 |
| Njoroge, M | 1 |
| Laing, L | 1 |
| Machado, M | 1 |
| Prudêncio, M | 1 |
| Reader, J | 1 |
| Botha, M | 1 |
| Nondaba, S | 1 |
| Birkholtz, LM | 1 |
| Lauterbach, S | 1 |
| Churchyard, A | 1 |
| Coetzer, TL | 1 |
| Burrows, JN | 1 |
| Yeates, C | 1 |
| Denti, P | 1 |
| Wiesner, L | 2 |
| Egan, TJ | 2 |
| Wittlin, S | 1 |
| Chibale, K | 2 |
| Blank, BR | 1 |
| Gut, J | 1 |
| Rosenthal, PJ | 2 |
| Renslo, AR | 1 |
| Joshi, MC | 1 |
| Nsumiwa, S | 1 |
| Ndove, J | 1 |
| Taylor, D | 1 |
| Hunter, R | 1 |
| Mpimbaza, A | 1 |
| Staedke, SG | 1 |
| Ndeezi, G | 1 |
| Byarugaba, J | 1 |
4 other studies available for midazolam and Infections, Plasmodium
| Article | Year |
|---|---|
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model.
Topics: Animals; Antimalarials; Benzimidazoles; Life Cycle Stages; Malaria; Male; Mice; Plasmodium berghei; | 2017 |
Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane.
Topics: Animals; Antimalarials; Female; Ferrous Compounds; Heterocyclic Compounds, 1-Ring; Malaria; Mice; Pe | 2017 |
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice.
Topics: Administration, Oral; Aminopyridines; Aminoquinolines; Animals; Antimalarials; Cell Membrane Permeab | 2017 |
Predictors of anti-convulsant treatment failure in children presenting with malaria and prolonged seizures in Kampala, Uganda.
Topics: Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Malaria; Male; Midazolam | 2009 |