midazolam has been researched along with Infarction, Middle Cerebral Artery in 5 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To quantify effects of a loading dose of midazolam and lidocaine on the EEG frequency spectrum of full-term neonates with perinatal arterial ischemic stroke (PAIS), 11 full-term infants underwent multi-channel amplitude-integrated EEG (aEEG) and EEG recordings." | 7.78 | Effects of midazolam and lidocaine on spectral properties of the EEG in full-term neonates with stroke. ( Andriessen, P; Dankers, F; de Vries, L; Janssen, F; Jennekens, W; Niemarkt, H; Toet, M; van der Aa, N; van Pul, C, 2012) |
| "Midazolam (MDZ) is a benzodiazepine drug that is clinically used during surgical procedures and for the treatment of insomnia, with a potential ability to treat stroke." | 5.51 | Neuroprotective effects of midazolam on focal cerebral ischemia in rats through anti‑apoptotic mechanisms. ( Chen, Z; Dai, M; Kang, F; Meng, Y; Wang, X; Yu, H, 2019) |
| " To quantify effects of a loading dose of midazolam and lidocaine on the EEG frequency spectrum of full-term neonates with perinatal arterial ischemic stroke (PAIS), 11 full-term infants underwent multi-channel amplitude-integrated EEG (aEEG) and EEG recordings." | 3.78 | Effects of midazolam and lidocaine on spectral properties of the EEG in full-term neonates with stroke. ( Andriessen, P; Dankers, F; de Vries, L; Janssen, F; Jennekens, W; Niemarkt, H; Toet, M; van der Aa, N; van Pul, C, 2012) |
| "Midazolam (MDZ) is a benzodiazepine drug that is clinically used during surgical procedures and for the treatment of insomnia, with a potential ability to treat stroke." | 1.51 | Neuroprotective effects of midazolam on focal cerebral ischemia in rats through anti‑apoptotic mechanisms. ( Chen, Z; Dai, M; Kang, F; Meng, Y; Wang, X; Yu, H, 2019) |
| "Midazolam is an anesthetic agent commonly used during clinical and surgical procedures, which has been shown to exert ROS‑suppressing and apoptosis‑modulating pharmacological activities in various cellular systems." | 1.46 | Midazolam anesthesia protects neuronal cells from oxidative stress-induced death via activation of the JNK-ERK pathway. ( Guo, F; Liu, JS; Liu, JY; Wang, Y; Wu, HL, 2017) |
| "Midazolam at a lower dose (10 mg/kg) had no significant effects." | 1.35 | Effects of midazolam on brain injury after transient focal cerebral ischemia in rats*. ( Cottrell, JE; Kass, IS; Lei, B; Popp, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, H | 1 |
| Wang, X | 1 |
| Kang, F | 1 |
| Chen, Z | 1 |
| Meng, Y | 1 |
| Dai, M | 1 |
| Liu, JY | 1 |
| Guo, F | 1 |
| Wu, HL | 1 |
| Wang, Y | 1 |
| Liu, JS | 1 |
| Lei, B | 1 |
| Popp, S | 1 |
| Cottrell, JE | 1 |
| Kass, IS | 1 |
| Jennekens, W | 1 |
| Dankers, F | 1 |
| Janssen, F | 1 |
| Toet, M | 1 |
| van der Aa, N | 1 |
| Niemarkt, H | 1 |
| van Pul, C | 1 |
| de Vries, L | 1 |
| Andriessen, P | 1 |
| Zhang, PB | 1 |
| Liu, Y | 1 |
| Li, J | 1 |
| Chen, XL | 1 |
| Tian, YF | 1 |
| Sun, JJ | 1 |
| Liu, JX | 1 |
5 other studies available for midazolam and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Neuroprotective effects of midazolam on focal cerebral ischemia in rats through anti‑apoptotic mechanisms.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Gene Expression Regulation; Glutamic Acid; Infarction, Mi | 2019 |
Midazolam anesthesia protects neuronal cells from oxidative stress-induced death via activation of the JNK-ERK pathway.
Topics: Adjuvants, Anesthesia; Animals; Apoptosis; Cell Death; Cell Survival; Cells, Cultured; Female; Infar | 2017 |
Effects of midazolam on brain injury after transient focal cerebral ischemia in rats*.
Topics: Animals; Blood Pressure; Brain; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Hemog | 2009 |
Effects of midazolam and lidocaine on spectral properties of the EEG in full-term neonates with stroke.
Topics: Anticonvulsants; Brain Ischemia; Data Interpretation, Statistical; Electroencephalography; Epilepsy; | 2012 |
[Effects of ketamine-midazolam anesthesia on focal cerebral ischemic injury in rats].
Topics: Adjuvants, Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Apoptosis; Infarct | 2004 |