midazolam has been researched along with Infant, Newborn, Diseases in 9 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since midazolam is frequently used in neonates for sedation during various examinations, future investigations on the selection of appropriate drugs and dosage for sedation in neonates, including the usage of midazolam, are necessary." | 5.37 | [Paroxysmal automatic movements mimicking neonatal seizures induced by midazolam]. ( Arakaki, Y; Ishizaki, Y; Mimaki, N; Ohtsuka, Y; Watabe, S, 2011) |
| "Neonatal stroke is the second cause of acute symptomatic neonatal seizures after hypoxic-ischemic encephalopathy." | 2.82 | Efficacy of the anti-seizure medications in acute symptomatic neonatal seizures caused by stroke. A systematic review. ( Criscione, R; Falsaperla, R; Marino, S; Pisani, F; Praticò, A; Ruggieri, M; Sortino, V, 2022) |
| " Since midazolam is frequently used in neonates for sedation during various examinations, future investigations on the selection of appropriate drugs and dosage for sedation in neonates, including the usage of midazolam, are necessary." | 1.37 | [Paroxysmal automatic movements mimicking neonatal seizures induced by midazolam]. ( Arakaki, Y; Ishizaki, Y; Mimaki, N; Ohtsuka, Y; Watabe, S, 2011) |
| " There was a large interindividual variability for the pharmacokinetic parameters." | 1.29 | Population pharmacokinetics of midazolam in neonates. ( Betremieux, P; Burtin, P; Desplanques, L; Girard, P; Jacqz-Aigrain, E; Lenclen, R; Magny, JF; Mussat, P; Tehiry, C, 1994) |
| "Midazolam is a water soluble benzodiazepine, with a short elimination half-life in adults and children." | 1.28 | Pharmacokinetics of midazolam in critically ill neonates. ( Jacqz-Aigrain, E; Robieux, I; Wood, C, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Sortino, V | 1 |
| Praticò, A | 1 |
| Marino, S | 1 |
| Criscione, R | 1 |
| Ruggieri, M | 1 |
| Pisani, F | 1 |
| Falsaperla, R | 1 |
| Moeller, AA | 1 |
| Stefanescu, AR | 1 |
| Stefanescu, BM | 1 |
| Golomb, MR | 1 |
| Boyle, FA | 1 |
| Buss, WF | 1 |
| Rose, RS | 1 |
| Wing, SE | 1 |
| Werther, T | 1 |
| Olischar, M | 2 |
| Giordano, V | 1 |
| Czaba, C | 1 |
| Waldhoer, T | 1 |
| Berger, A | 1 |
| Pollak, A | 1 |
| Deindl, P | 1 |
| Wildschut, ED | 1 |
| Hanekamp, MN | 1 |
| Vet, NJ | 1 |
| Houmes, RJ | 1 |
| Ahsman, MJ | 1 |
| Mathot, RA | 1 |
| de Wildt, SN | 1 |
| Tibboel, D | 1 |
| Ishizaki, Y | 1 |
| Watabe, S | 1 |
| Mimaki, N | 1 |
| Arakaki, Y | 1 |
| Ohtsuka, Y | 1 |
| Davidson, AJ | 1 |
| Lee, KJ | 1 |
| Hunt, RW | 1 |
| Wolf, AR | 1 |
| Burtin, P | 1 |
| Jacqz-Aigrain, E | 2 |
| Girard, P | 1 |
| Lenclen, R | 1 |
| Magny, JF | 1 |
| Betremieux, P | 1 |
| Tehiry, C | 1 |
| Desplanques, L | 1 |
| Mussat, P | 1 |
| Wood, C | 1 |
| Robieux, I | 1 |
1 review available for midazolam and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Efficacy of the anti-seizure medications in acute symptomatic neonatal seizures caused by stroke. A systematic review.
Topics: Anticonvulsants; Bumetanide; Epilepsy; Humans; Infant, Newborn; Infant, Newborn, Diseases; Levetirac | 2022 |
1 trial available for midazolam and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Effects of morphine and midazolam on sleep-wake cycling in amplitude-integrated electroencephalography in post-surgical neonates ≥ 32 weeks of gestational age.
Topics: Analgesics, Opioid; Electroencephalography; Female; Gestational Age; Humans; Hypnotics and Sedatives | 2012 |
7 other studies available for midazolam and Infant, Newborn, Diseases
| Article | Year |
|---|---|
A Standardized, 3-Tiered, Seizure Burden-Based Protocol for the Treatment of Neonatal Seizures.
Topics: Electroencephalography; Epilepsy; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Midazo | 2023 |
Bispectral index and lower margin amplitude of the amplitude-integrated electroencephalogram in neonates.
Topics: Analgesics, Opioid; Brain Waves; Deep Sedation; Electroencephalography; Female; Fentanyl; Humans; Hy | 2015 |
Feasibility of sedation and analgesia interruption following cannulation in neonates on extracorporeal membrane oxygenation.
Topics: Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Catheterization; Consciousn | 2010 |
[Paroxysmal automatic movements mimicking neonatal seizures induced by midazolam].
Topics: Diagnosis, Differential; Dyskinesia, Drug-Induced; Female; Humans; Hypnotics and Sedatives; Infant, | 2011 |
Neonatal sedation: more art than science.
Topics: Critical Illness; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Newborn, Diseases; Infus | 1994 |
Population pharmacokinetics of midazolam in neonates.
Topics: Critical Illness; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Midazolam; Models, | 1994 |
Pharmacokinetics of midazolam in critically ill neonates.
Topics: Chromatography, High Pressure Liquid; Critical Care; Diazepam; Half-Life; Humans; Infant, Newborn; I | 1990 |