midazolam has been researched along with Hypoventilation in 8 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Hypoventilation: A reduction in the amount of air entering the pulmonary alveoli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary objective of this investigation was to examine the effect of ketamine on hypoventilation in patients receiving deep sedation for surgery with midazolam and propofol." | 9.19 | The effect of ketamine on hypoventilation during deep sedation with midazolam and propofol: a randomised, double-blind, placebo-controlled trial. ( Ahmad, S; De Oliveira, GS; Fitzgerald, PC; Hansen, N; McCarthy, RJ, 2014) |
| "To characterize the profiles of alveolar hypoventilation during colonoscopies performed under sedoanalgesia with a combination of alfentanil and either midazolam or propofol." | 5.16 | Carbon dioxide accumulation during analgosedated colonoscopy: comparison of propofol and midazolam. ( Beglinger, C; Heuss, LT; Sugandha, SP, 2012) |
| " With the little therapeutic use observed with the given premedication, a more widespread application of the substance in this dosage cannot be recommended, particularly when taking into account the possibility of complications and the loss of the patients's fitness to drive for the next twelve hours." | 2.67 | [The question of oral sedation using midazolam in outpatient dental surgery]. ( Dietrich, U; Fischer, W; Wahlmann, UW, 1992) |
| "High midazolam dose was associated with lower IPI levels during the procedure." | 1.42 | The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children. ( Adiv, OE; Garah, J; Rosen, I; Shaoul, R, 2015) |
| "Midazolam was the intravenous sedative used by a third of all respondents and 13% also used an additional intravenous agent, usually pethidine." | 1.28 | Sedation for upper gastrointestinal endoscopy: results of a nationwide survey. ( Bell, GD; Daneshmend, TK; Logan, RF, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Oliveira, GS | 1 |
| Fitzgerald, PC | 1 |
| Hansen, N | 1 |
| Ahmad, S | 1 |
| McCarthy, RJ | 1 |
| Garah, J | 1 |
| Adiv, OE | 1 |
| Rosen, I | 1 |
| Shaoul, R | 1 |
| Heuss, LT | 1 |
| Sugandha, SP | 1 |
| Beglinger, C | 1 |
| Chhajed, PN | 1 |
| Kaegi, B | 1 |
| Rajasekaran, R | 1 |
| Tamm, M | 1 |
| Litman, RS | 1 |
| Kottra, JA | 1 |
| Berkowitz, RJ | 1 |
| Ward, DS | 1 |
| Haberer, JP | 1 |
| Wahlmann, UW | 1 |
| Dietrich, U | 1 |
| Fischer, W | 1 |
| Daneshmend, TK | 1 |
| Bell, GD | 1 |
| Logan, RF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Ketamine in The Prevention of Hypoventilation in Patients With and Without a Positive Berlin Questionnaire Undergoing Deep Sedation[NCT01535976] | 54 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Bronchoscopy Procedures Under Sedation[NCT05137587] | 60 participants (Actual) | Interventional | 2022-09-01 | Completed | |||
| Comparison of Efficacy and Safety of the Postoperative Analgesia Methods for Supratentorial Craniotomy by Integrated Pulmonary Index (IPI)[NCT02929147] | Phase 4 | 90 participants (Anticipated) | Interventional | 2016-11-30 | Not yet recruiting | ||
| Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Endoscopy Procedures Under Sedation[NCT05137574] | 60 participants (Actual) | Interventional | 2021-05-10 | Completed | |||
| [NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
| Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Subjects receiving intraoperative ketamine in addition to propofol will demonstrate less hypoventilation during the surgical procedure. (NCT01535976)
Timeframe: 8 hours
| Intervention | % time (Median) |
|---|---|
| Ketamine | 1.2 |
| Placebo | 65 |
3 trials available for midazolam and Hypoventilation
| Article | Year |
|---|---|
The effect of ketamine on hypoventilation during deep sedation with midazolam and propofol: a randomised, double-blind, placebo-controlled trial.
Topics: Adult; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Hypoventilation; Ketamine; Mida | 2014 |
Carbon dioxide accumulation during analgosedated colonoscopy: comparison of propofol and midazolam.
Topics: Aged; Alfentanil; Analgesics, Opioid; Biomarkers; Blood Gas Monitoring, Transcutaneous; Carbon Dioxi | 2012 |
[The question of oral sedation using midazolam in outpatient dental surgery].
Topics: Anesthesia, Dental; Automobile Driving; Blood Pressure; Conscious Sedation; Heart Rate; Humans; Hypo | 1992 |
5 other studies available for midazolam and Hypoventilation
| Article | Year |
|---|---|
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
Detection of hypoventilation during thoracoscopy: combined cutaneous carbon dioxide tension and oximetry monitoring with a new digital sensor.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Blood Gas Monitoring, Transcutaneous; Conscious S | 2005 |
Breathing patterns and levels of consciousness in children during administration of nitrous oxide after oral midazolam premedication.
Topics: Adjuvants, Anesthesia; Administration, Oral; Airway Obstruction; Analgesia; Anesthesia, Inhalation; | 1997 |
[Premedication and sedation complications during ophthalmic anesthesia].
Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anesthesi | 2000 |
Sedation for upper gastrointestinal endoscopy: results of a nationwide survey.
Topics: Benzodiazepines; Conscious Sedation; Endoscopy, Gastrointestinal; Heart Arrest; Humans; Hypoventilat | 1991 |