midazolam has been researched along with Hypoplastic Left Heart Syndrome in 3 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Hypoplastic Left Heart Syndrome: A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapy of hypoplastic left heart syndrome (HLHS) consists of the staged Norwood procedure or cardiac transplantation." | 1.32 | A combined stage 1 and 2 repair for hypoplastic left heart syndrome: anaesthetic considerations. ( Akintürk, H; Bräu, M; Hempelmann, G; Michel-Behnke, I; Müller, M; Schindler, E; Scholz, S; Schranz, D; Thul, J; Valeske, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michel, J | 1 |
| Hofbeck, M | 1 |
| Gerbig, I | 1 |
| Icheva, V | 1 |
| Heimberg, E | 1 |
| Jost, W | 1 |
| Schlensak, C | 1 |
| Kumpf, M | 1 |
| Blumenstock, G | 1 |
| Neunhoeffer, F | 1 |
| Müller, M | 1 |
| Akintürk, H | 1 |
| Schindler, E | 1 |
| Bräu, M | 1 |
| Scholz, S | 1 |
| Valeske, K | 1 |
| Michel-Behnke, I | 1 |
| Thul, J | 1 |
| Schranz, D | 1 |
| Hempelmann, G | 1 |
| Weber, MD | 1 |
| Thammasitboon, S | 1 |
| Rosen, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Protocolized Initiation of Clonidine to Prevent Dexmedetomidine Withdrawal: A Prospective Cohort Study[NCT05575219] | Phase 4 | 300 participants (Anticipated) | Interventional | 2022-10-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for midazolam and Hypoplastic Left Heart Syndrome
| Article | Year |
|---|---|
Nurse-driven analgesia and sedation in pediatric patients with univentricular hearts requiring extracorporeal life support after first-stage palliation surgery: A pilot study.
Topics: Advanced Cardiac Life Support; Analgesia; Analgesics, Opioid; Cardiac Surgical Procedures; Conscious | 2017 |
A combined stage 1 and 2 repair for hypoplastic left heart syndrome: anaesthetic considerations.
Topics: Anesthetics, Intravenous; Fentanyl; Humans; Hypoplastic Left Heart Syndrome; Infant; Midazolam; Neur | 2003 |
Acute discontinuation syndrome from dexmedetomidine after protracted use in a pediatric patient.
Topics: Analgesia, Epidural; Blood Pressure; Cardiac Catheterization; Cardiovascular Diseases; Child, Presch | 2008 |