midazolam has been researched along with Hypoalbuminemia in 2 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Hypoalbuminemia: A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " To find clinically relevant parameters for dose individualization, we performed a pharmacokinetic study on midazolam, 1OH-midazolam (1-OH-M) and 1OH-midazolam-glucuronide (1-OH-MG) in terminally ill patients." | 2.84 | Hypoalbuminaemia and decreased midazolam clearance in terminally ill adult patients, an inflammatory effect? ( Baar, FPM; de Winter, BCM; Franken, LG; Koch, BCP; Masman, AD; Mathot, RAA; Tibboel, D; van Gelder, T, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ersoy, A | 1 |
| Kara, D | 1 |
| Ervatan, Z | 1 |
| Çakırgöz, M | 1 |
| Kıran, Ö | 1 |
| Franken, LG | 1 |
| Masman, AD | 1 |
| de Winter, BCM | 1 |
| Baar, FPM | 1 |
| Tibboel, D | 1 |
| van Gelder, T | 1 |
| Koch, BCP | 1 |
| Mathot, RAA | 1 |
2 trials available for midazolam and Hypoalbuminemia
| Article | Year |
|---|---|
Sedation in hypoalbuminemic geriatric patients under spinal anesthesia in hip surgery. Midazolam or Propofol?
Topics: Age Factors; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Spinal; Arthroplasty, | 2015 |
Hypoalbuminaemia and decreased midazolam clearance in terminally ill adult patients, an inflammatory effect?
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Drug Dosage | 2017 |