midazolam has been researched along with Hyperlipemia in 3 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam can also cause paradoxical reactions, including increased agitation, poor co-operation and aggressive or violent behaviour, which has been successfully managed with flumazenil." | 2.42 | Toxicity of intravenous anaesthetics. ( Short, TG; Young, Y, 2003) |
| "Hyperlipidemia (HL) was previously shown to lower liver uptake of the more potent (-) enantiomer of ketoconazole (KTZ) in rat." | 1.37 | Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat. ( Brocks, DR; Hamdy, DA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamdy, DA | 1 |
| Brocks, DR | 1 |
| Short, TG | 1 |
| Young, Y | 1 |
| Alfa, JA | 1 |
| Bamgbade, OA | 1 |
1 review available for midazolam and Hyperlipemia
| Article | Year |
|---|---|
Toxicity of intravenous anaesthetics.
Topics: Anesthetics, Intravenous; Humans; Hyperlipidemias; Ketamine; Midazolam; Nervous System; Pancreatitis | 2003 |
2 other studies available for midazolam and Hyperlipemia
| Article | Year |
|---|---|
Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat.
Topics: Animals; Blood Proteins; Drug Interactions; Hyperlipidemias; Ketoconazole; Male; Midazolam; Protein | 2011 |
Acute myoclonus following spinal anaesthesia.
Topics: Acute Disease; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, Intr | 2008 |