midazolam has been researched along with Hyperactivity, Motor in 4 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " For both experiments, cumulative morphine anti-nociceptive dose-response (ED50) was tested and hyperactive behaviors such as jumping and scratching were recorded." | 1.40 | Midazolam exacerbates morphine tolerance and morphine-induced hyperactive behaviors in young rats with burn injury. ( Chen, L; Mao, J; Martyn, JA; Song, L; Wang, S; Zuo, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, L | 1 |
| Wang, S | 1 |
| Zuo, Y | 1 |
| Chen, L | 1 |
| Martyn, JA | 1 |
| Mao, J | 1 |
| Tae, CH | 1 |
| Kang, KJ | 1 |
| Min, BH | 1 |
| Ahn, JH | 1 |
| Kim, S | 1 |
| Lee, JH | 1 |
| Rhee, PL | 1 |
| Kim, JJ | 1 |
| Kovacs, N | 1 |
| Balas, I | 1 |
| Janszky, J | 1 |
| Simon, M | 1 |
| Fekete, S | 1 |
| Komoly, S | 1 |
| Morris, HV | 1 |
| Dawson, GR | 1 |
| Reynolds, DS | 1 |
| Atack, JR | 1 |
| Rosahl, TW | 1 |
| Stephens, DN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Propofol vs. Midazolam With Propofol for Sedative Endoscopy in Patients With Previous Paradoxical Reaction to Midazolam[NCT04072328] | Phase 2 | 30 participants (Actual) | Interventional | 2018-10-19 | Completed | ||
| Effect of an Adjunctive Sedative for the Patients With Histories of Paradoxical Reaction to Midazolam During Sedative Endoscopy[NCT03940391] | 220 participants (Anticipated) | Interventional | 2019-05-01 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for midazolam and Hyperactivity, Motor
| Article | Year |
|---|---|
Midazolam exacerbates morphine tolerance and morphine-induced hyperactive behaviors in young rats with burn injury.
Topics: Analgesics, Opioid; Animals; Burns; Drug Tolerance; Hyperalgesia; Hyperkinesis; Hypnotics and Sedati | 2014 |
Paradoxical reaction to midazolam in patients undergoing endoscopy under sedation: Incidence, risk factors and the effect of flumazenil.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Endoscopy, Gastrointestinal; Female; Flumazenil; Hostilit | 2014 |
Paradoxical reaction to midazolam in patients undergoing endoscopy under sedation: Incidence, risk factors and the effect of flumazenil.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Endoscopy, Gastrointestinal; Female; Flumazenil; Hostilit | 2014 |
Paradoxical reaction to midazolam in patients undergoing endoscopy under sedation: Incidence, risk factors and the effect of flumazenil.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Endoscopy, Gastrointestinal; Female; Flumazenil; Hostilit | 2014 |
Paradoxical reaction to midazolam in patients undergoing endoscopy under sedation: Incidence, risk factors and the effect of flumazenil.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Endoscopy, Gastrointestinal; Female; Flumazenil; Hostilit | 2014 |
Status dystonicus in tardive dystonia successfully treated by bilateral deep brain stimulation.
Topics: Adolescent; Antipsychotic Agents; Clonazepam; Deep Brain Stimulation; Disability Evaluation; Electro | 2011 |
Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine.
Topics: Animals; Autoradiography; Azides; Benzodiazepines; Brain Chemistry; Central Nervous System Stimulant | 2008 |