midazolam has been researched along with Heart Failure in 11 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The longterm effects of ketamine on haemodynamic parameters and exogenous catecholamine requirements were studied in twenty-five critically ill patients with catecholamine-dependent heart failure." | 9.08 | Adverse cardiovascular effects of ketamine infusion in patients with catecholamine-dependent heart failure. ( Christ, G; Heinz, G; Kratochwill, C; Merhaut, C; Mundigler, G; Siostrzonek, P; Zehetgruber, M, 1997) |
| "We herein report a case of dyspnea in an older patient with end-stage heart failure and renal insufficiency successfully controlled with high-dose oxycodone plus midazolam." | 8.31 | [The use of high-dose oxycodone with midazolam for dyspnea due to end-stage heart failure in an older patient with renal insufficiency]. ( Konishi, H; Mano, A; Matsui, H; Nagasawa, Y; Saito, E, 2023) |
| "The disposition of midazolam was investigated in six patients with congestive heart failure (CHF) and six age- and weight-matched healthy subjects by administering two single doses of the drug (3." | 7.68 | The pharmacokinetics of midazolam in patients with congestive heart failure. ( Boudoulas, H; Fukuda, EK; Leier, CV; Patel, IH; Smith, DF; Soni, PP, 1990) |
| "The longterm effects of ketamine on haemodynamic parameters and exogenous catecholamine requirements were studied in twenty-five critically ill patients with catecholamine-dependent heart failure." | 5.08 | Adverse cardiovascular effects of ketamine infusion in patients with catecholamine-dependent heart failure. ( Christ, G; Heinz, G; Kratochwill, C; Merhaut, C; Mundigler, G; Siostrzonek, P; Zehetgruber, M, 1997) |
| "We herein report a case of dyspnea in an older patient with end-stage heart failure and renal insufficiency successfully controlled with high-dose oxycodone plus midazolam." | 4.31 | [The use of high-dose oxycodone with midazolam for dyspnea due to end-stage heart failure in an older patient with renal insufficiency]. ( Konishi, H; Mano, A; Matsui, H; Nagasawa, Y; Saito, E, 2023) |
| "The disposition of midazolam was investigated in six patients with congestive heart failure (CHF) and six age- and weight-matched healthy subjects by administering two single doses of the drug (3." | 3.68 | The pharmacokinetics of midazolam in patients with congestive heart failure. ( Boudoulas, H; Fukuda, EK; Leier, CV; Patel, IH; Smith, DF; Soni, PP, 1990) |
| "Patients with congestive heart failure had a greater drop in oxygen saturation compared with patients who were not in heart failure (p < 0." | 2.68 | Routine arterial oxygen saturation monitoring is not necessary during transesophageal echocardiography. ( Ikonomidis, I; Joshi, J; Kassimatis, A; Nihoyannopoulos, P; Tsoukas, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Domínguez-Rodríguez, A | 1 |
| Suero-Mendez, C | 1 |
| Burillo-Putze, G | 1 |
| Gil, V | 1 |
| Calvo-Rodriguez, R | 1 |
| Piñera-Salmeron, P | 1 |
| Llorens, P | 1 |
| Martín-Sánchez, FJ | 1 |
| Abreu-Gonzalez, P | 1 |
| Miró, Ò | 1 |
| Neto Gonçalves, T | 1 |
| Margarida Andrade, M | 1 |
| Konishi, H | 1 |
| Nagasawa, Y | 1 |
| Matsui, H | 1 |
| Mano, A | 1 |
| Saito, E | 1 |
| Hamatani, Y | 1 |
| Nakai, E | 1 |
| Nakamura, E | 1 |
| Miyata, M | 1 |
| Kawano, Y | 1 |
| Takada, Y | 1 |
| Anchi, Y | 1 |
| Funabashi, S | 1 |
| Hirayama, A | 1 |
| Kuroda, K | 1 |
| Amano, M | 1 |
| Sugano, Y | 1 |
| Anzai, T | 1 |
| Izumi, C | 1 |
| Berry, CJ | 1 |
| Thedens, DR | 1 |
| Light-McGroary, K | 1 |
| Miller, JD | 1 |
| Kutschke, W | 1 |
| Zimmerman, KA | 1 |
| Weiss, RM | 1 |
| Shekar, K | 1 |
| Roberts, JA | 1 |
| Mullany, DV | 1 |
| Corley, A | 1 |
| Fisquet, S | 1 |
| Bull, TN | 1 |
| Barnett, AG | 1 |
| Fraser, JF | 1 |
| Olivier, P | 1 |
| D'Attellis, N | 1 |
| Baron, JF | 1 |
| Kassimatis, A | 1 |
| Tsoukas, A | 1 |
| Ikonomidis, I | 1 |
| Joshi, J | 1 |
| Nihoyannopoulos, P | 1 |
| Christ, G | 1 |
| Mundigler, G | 1 |
| Merhaut, C | 1 |
| Zehetgruber, M | 1 |
| Kratochwill, C | 1 |
| Heinz, G | 1 |
| Siostrzonek, P | 1 |
| Kubota, T | 1 |
| Hirota, K | 1 |
| Yoshida, H | 1 |
| Yatsu, Y | 1 |
| Maeda, A | 1 |
| Matsuki, A | 1 |
| Patel, IH | 1 |
| Soni, PP | 1 |
| Fukuda, EK | 1 |
| Smith, DF | 1 |
| Leier, CV | 1 |
| Boudoulas, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane[NCT05680545] | 10 participants (Anticipated) | Interventional | 2024-07-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for midazolam and Heart Failure
| Article | Year |
|---|---|
Midazolam versus morphine in acute cardiogenic pulmonary oedema: results of a multicentre, open-label, randomized controlled trial.
Topics: Adolescent; Heart Failure; Hospital Mortality; Humans; Midazolam; Morphine; Pulmonary Edema | 2022 |
Morphine use in acute cardiogenic pulmonary oedema: is MIMO trial enough to change practice? Letter regarding the article 'Midazolam versus morphine in acute cardiogenic pulmonary oedema: results of a multicentre, open-label, randomized controlled trial'.
Topics: Acute Disease; Heart Failure; Humans; Midazolam; Morphine; Pulmonary Edema | 2022 |
Survey of Palliative Sedation at End of Life in Terminally Ill Heart Failure Patients - A Single-Center Experience of 5-Year Follow-up.
Topics: Aged; Aged, 80 and over; Dexmedetomidine; Female; Follow-Up Studies; Heart Failure; Humans; Male; Mi | 2019 |
Routine arterial oxygen saturation monitoring is not necessary during transesophageal echocardiography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Echocardiography, Transesophag | 1997 |
Adverse cardiovascular effects of ketamine infusion in patients with catecholamine-dependent heart failure.
Topics: Aged; Anesthetics, Dissociative; Anesthetics, Intravenous; Catecholamines; Critical Care; Drug Inter | 1997 |
Haemodynamic comparison of propofol-fentanyl anaesthesia with midazolam-fentanyl anaesthesia in CABG patients without preoperative heart failure.
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Coronary Artery Bypass; Female; Fentanyl; H | 2000 |
5 other studies available for midazolam and Heart Failure
| Article | Year |
|---|---|
[The use of high-dose oxycodone with midazolam for dyspnea due to end-stage heart failure in an older patient with renal insufficiency].
Topics: Aged, 80 and over; Dyspnea; Female; Heart Failure; Humans; Midazolam; Oxycodone; Renal Insufficiency | 2023 |
Effects of deep sedation or general anesthesia on cardiac function in mice undergoing cardiovascular magnetic resonance.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Body Temperature; Conscious Sedation; Deep Se | 2009 |
Increased sedation requirements in patients receiving extracorporeal membrane oxygenation for respiratory and cardiorespiratory failure.
Topics: Adolescent; Adult; Aged; APACHE; Extracorporeal Membrane Oxygenation; Female; Heart Failure; Humans; | 2012 |
[Midazolam in patients with cardiac insufficiency].
Topics: Anesthesia; Anesthetics; Drug Combinations; Fentanyl; Heart Failure; Hemodynamics; Humans; Midazolam | 1995 |
The pharmacokinetics of midazolam in patients with congestive heart failure.
Topics: Adult; Blood Pressure; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Heart Failure; Heart | 1990 |