midazolam has been researched along with Heart Diseases in 13 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam was administered during the procedure by staff who were blinded to the state/trait anxiety scores and the type of consent the patient had received." | 2.68 | Effect of informed consent on anxiety in patients undergoing diagnostic electrophysiology studies. ( Goldberger, JJ; Kadish, AH; Kruse, J; Parker, MA, 1997) |
| "All deceased patients experienced generalized convulsive status epilepticus and failure of anesthetic tapering-off, significantly higher than survivors." | 1.72 | Factors associated with mortality in patients with super-refractory status epilepticus. ( Chien, ME; Fang, YT; Hsu, KS; Huang, CW; Lee, TL; Lin, SH; Tu, YH; Wu, YJ, 2022) |
| "Prolonged dexmedetomidine administration in children with heart disease appears to be safe and is associated with decreased opioid and benzodiazepine requirement and decreased inotropic support." | 1.38 | Safety and efficacy of prolonged dexmedetomidine use in critically ill children with heart disease*. ( Gossett, JM; Gupta, P; Roth, SJ; Sabati, A; Tesoro, TM; Tobias, JD; Whiteside, W, 2012) |
| "Midazolam is a broadly used drug that can enhance tolerance to transesophageal echocardiography (TEE) in patients with cardiac conditions." | 1.31 | Central-nervous side effects of midazolam during transesophageal echocardiography. ( Bartel, T; Eggebrecht, H; Erbel, R; Philipp, T; Wenzel, RR, 2002) |
| "Midazolam appears to be a valuable alternative to conventional induction agents without adverse effects on the cardiovascular system." | 1.26 | Haemodynamic responses to induction of anaesthesia using midazolam in cardiac surgical patients. ( Hess, W; Schulte-Sasse, U; Tarnow, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, YT | 1 |
| Lee, TL | 1 |
| Tu, YH | 1 |
| Lin, SH | 1 |
| Chien, ME | 1 |
| Huang, CW | 1 |
| Hsu, KS | 1 |
| Wu, YJ | 1 |
| Gupta, P | 1 |
| Whiteside, W | 1 |
| Sabati, A | 1 |
| Tesoro, TM | 1 |
| Gossett, JM | 1 |
| Tobias, JD | 1 |
| Roth, SJ | 1 |
| Wenzel, RR | 1 |
| Bartel, T | 1 |
| Eggebrecht, H | 1 |
| Philipp, T | 1 |
| Erbel, R | 1 |
| Masue, T | 1 |
| Shimonaka, H | 1 |
| Fukao, I | 1 |
| Kasuya, S | 1 |
| Kasuya, Y | 1 |
| Dohi, S | 1 |
| Boileau, S | 1 |
| Laxenaire, MC | 1 |
| Borgo, J | 1 |
| Royer, E | 1 |
| Aliot, E | 1 |
| Schulte-Sasse, U | 1 |
| Hess, W | 1 |
| Tarnow, J | 1 |
| Clergue, F | 1 |
| Pávek, V | 1 |
| Bígl, P | 1 |
| Hess, L | 1 |
| Goldberger, JJ | 1 |
| Kruse, J | 1 |
| Parker, MA | 1 |
| Kadish, AH | 1 |
| Kovoor, P | 1 |
| Porter, R | 1 |
| Uther, JB | 1 |
| Ross, DL | 1 |
| Kurokawa, S | 1 |
| Fukuda, S | 1 |
| Shimoji, K | 1 |
| Middlehurst, RJ | 1 |
| Gibbs, A | 1 |
| Walton, G | 1 |
| Yazawa, K | 1 |
| Adachi, W | 1 |
| Owa, M | 1 |
| Koide, N | 1 |
| Hanazaki, K | 1 |
| Kajikawa, S | 1 |
| Kobayashi, S | 1 |
| Amano, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy[NCT04528173] | Phase 4 | 550 participants (Anticipated) | Interventional | 2020-07-22 | Recruiting | ||
| Auricular Acupressure as an Adjunct Treatment for Opioid Tapering in a Pediatric Cardiac Intensive Care Unit: A Pilot Feasibility Study[NCT05025384] | 40 participants (Actual) | Interventional | 2021-10-25 | Completed | |||
| Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies[NCT03182777] | 31 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for midazolam and Heart Diseases
| Article | Year |
|---|---|
Oral high-dose midazolam premedication for infants and children undergoing cardiovascular surgery.
Topics: Administration, Oral; Anesthetics, Intravenous; Anxiety; Cardiovascular Surgical Procedures; Child, | 2003 |
[Hemodynamic effects of midazolam and flunitrazepam used as induction agents in cardiac patients].
Topics: Adult; Anesthesia, Intravenous; Anesthetics; Anti-Anxiety Agents; Benzodiazepines; Cardiac Catheteri | 1982 |
Effect of informed consent on anxiety in patients undergoing diagnostic electrophysiology studies.
Topics: Anti-Anxiety Agents; Anxiety; Arrhythmias, Cardiac; Bradycardia; Cardiac Catheterization; Cardiac Ou | 1997 |
Cardiovascular risk: the safety of local anesthesia, vasoconstrictors, and sedation in heart disease.
Topics: Anesthesia, Dental; Anesthetics, Local; Arrhythmias, Cardiac; Blood Pressure; Conscious Sedation; El | 1999 |
Can sedation reduce the cardiac stress during gastrointestinal endoscopy? A study with non-invasive automated cardiac flow measurement by color Doppler echocardiography.
Topics: Adrenocorticotropic Hormone; Adult; Catecholamines; Echocardiography, Doppler, Color; Endoscopy, Gas | 2002 |
8 other studies available for midazolam and Heart Diseases
| Article | Year |
|---|---|
Factors associated with mortality in patients with super-refractory status epilepticus.
Topics: Anticonvulsants; Heart Diseases; Humans; Midazolam; Middle Aged; Retrospective Studies; Seizures; St | 2022 |
Safety and efficacy of prolonged dexmedetomidine use in critically ill children with heart disease*.
Topics: Blood Pressure; Child, Preschool; Critical Care; Critical Illness; Dexmedetomidine; Female; Heart Di | 2012 |
Safety and efficacy of prolonged dexmedetomidine use in critically ill children with heart disease*.
Topics: Blood Pressure; Child, Preschool; Critical Care; Critical Illness; Dexmedetomidine; Female; Heart Di | 2012 |
Safety and efficacy of prolonged dexmedetomidine use in critically ill children with heart disease*.
Topics: Blood Pressure; Child, Preschool; Critical Care; Critical Illness; Dexmedetomidine; Female; Heart Di | 2012 |
Safety and efficacy of prolonged dexmedetomidine use in critically ill children with heart disease*.
Topics: Blood Pressure; Child, Preschool; Critical Care; Critical Illness; Dexmedetomidine; Female; Heart Di | 2012 |
Central-nervous side effects of midazolam during transesophageal echocardiography.
Topics: Adult; Aged; Anesthetics, Intravenous; Central Nervous System Diseases; Dose-Response Relationship, | 2002 |
Haemodynamic responses to induction of anaesthesia using midazolam in cardiac surgical patients.
Topics: Adult; Aged; Anesthetics; Benzodiazepines; Blood Pressure; Coronary Artery Bypass; Coronary Disease; | 1982 |
[Use of midazolam in the patient with cardiac, neurologic or respiratory disease and the aged].
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics; Cardiac Surgical Procedures; Conscious Se | 1995 |
[5 years' experience with conscious sedation with midazolam (Dormicum Roche) in stomatology].
Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Conscious Sedation; Female; Heart Diseases; Humans; Hyp | 1995 |
Efficacy and safety of a new protocol for continuous infusion of midazolam and fentanyl and its effects on patient distress during electrophysiological studies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Clinical Protocols; Electrophy | 1997 |
[Anesthetic management of thrombectomy for left ventricular huge mobile thrombus].
Topics: Anesthesia, Intravenous; Cardiopulmonary Bypass; Echocardiography, Transesophageal; Fentanyl; Heart | 2000 |