midazolam has been researched along with Gastroesophageal Reflux in 5 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam was significantly associated with an increased risk of hiccups." | 1.38 | Sedation-associated hiccups in adults undergoing gastrointestinal endoscopy and colonoscopy. ( Changchien, CF; Liu, CC; Liu, PH; Lu, CY; Perng, DS, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balko, RA | 1 |
| Katzka, DA | 1 |
| Murray, JA | 1 |
| Alexander, JA | 1 |
| Mara, KC | 1 |
| Ravi, K | 1 |
| Liu, CC | 1 |
| Lu, CY | 1 |
| Changchien, CF | 1 |
| Liu, PH | 1 |
| Perng, DS | 1 |
| Wolfsen, HC | 1 |
| Hemminger, L | 1 |
| Stark, ME | 1 |
| Achem, SR | 1 |
| Loeb, DS | 1 |
| Woodward, TA | 1 |
| DeVault, KR | 1 |
| Meininger, DD | 1 |
| Byhahn, C | 1 |
| Heller, K | 1 |
| Gutt, CN | 1 |
| Westphal, K | 1 |
| Vanner, RG | 1 |
| Pryle, BJ | 1 |
| O'Dwyer, JP | 1 |
| Reynolds, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Upper Esophageal Sphincter Pressure Variation During Anesthesia Induction[NCT04413422] | 20 participants (Actual) | Observational | 2017-01-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for midazolam and Gastroesophageal Reflux
| Article | Year |
|---|---|
Same-day opioid administration in opiate naïve patients is not associated with opioid-induced esophageal dysfunction (OIED).
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Chest Pain; Conscious Sedation; Deglutiti | 2021 |
Sedation-associated hiccups in adults undergoing gastrointestinal endoscopy and colonoscopy.
Topics: Adult; Aged; Chi-Square Distribution; Colonoscopy; Dose-Response Relationship, Drug; Endoscopy, Gast | 2012 |
Resource utilization and procedure parameters for the Stretta procedure: comparison with endoscopic ultrasonography and colonoscopy.
Topics: Adjuvants, Anesthesia; Aged; Cohort Studies; Colonoscopy; Endoscopy, Digestive System; Endosonograph | 2003 |
Totally endoscopic Nissen fundoplication with a robotic system in a child.
Topics: Child; Endoscopy; Female; Fundoplication; Gastroesophageal Reflux; Humans; Midazolam; Monitoring, In | 2001 |
Upper oesophageal sphincter pressure and the intravenous induction of anaesthesia.
Topics: Adult; Anesthesia, Intravenous; Cricoid Cartilage; Esophagus; Female; Gastroesophageal Reflux; Human | 1992 |