midazolam has been researched along with Esophageal Varices in 8 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the efficacy and gastroenterologist/patient satisfaction of midazolam combined with oxycodone, relative to that of midazolam combined with sufentanil, for anesthesia during endoscopic injection sclerotherapy (EIS) in patients with cirrhosis and esophageal varices." | 9.27 | Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices. ( Chi, P; He, H; Luo, C; Quan, Z; Wang, L, 2018) |
| "Propofol-based sedation exacerbated MHE after EIS similarly to midazolam-based sedation in patients with liver cirrhosis." | 9.27 | Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( Hashimoto, M; Hikichi, T; Irie, H; Kikuchi, H; Konno, N; Nakamura, J; Obara, K; Ohira, H; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M; Watanabe, K, 2018) |
| "Midazolam sedation for upper gastrointestinal (GI) endoscopy exacerbates minimal hepatic encephalopathy (HE) in patients with liver cirrhosis, therefore an alternative drug regimen for these patients is warranted." | 9.14 | Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study. ( Frenz, MB; Lechowicz, I; Riphaus, A; Wehrmann, T, 2009) |
| "BACKGROUND The aim of the present study was to evaluate the effects of different doses of oxycodone during endoscopic injection sclerotherapy (EIS) for esophageal varices with painless sclerosing agents." | 8.02 | Different Doses of Oxycodone for Endoscopic Injection Sclerotherapy of Esophageal Varices. ( He, H; Quan, Z; Song, C; Yao, J; Zhou, C, 2021) |
| "We evaluated the efficacy and gastroenterologist/patient satisfaction of midazolam combined with oxycodone, relative to that of midazolam combined with sufentanil, for anesthesia during endoscopic injection sclerotherapy (EIS) in patients with cirrhosis and esophageal varices." | 5.27 | Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices. ( Chi, P; He, H; Luo, C; Quan, Z; Wang, L, 2018) |
| "Propofol-based sedation exacerbated MHE after EIS similarly to midazolam-based sedation in patients with liver cirrhosis." | 5.27 | Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( Hashimoto, M; Hikichi, T; Irie, H; Kikuchi, H; Konno, N; Nakamura, J; Obara, K; Ohira, H; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M; Watanabe, K, 2018) |
| "Midazolam sedation for upper gastrointestinal (GI) endoscopy exacerbates minimal hepatic encephalopathy (HE) in patients with liver cirrhosis, therefore an alternative drug regimen for these patients is warranted." | 5.14 | Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study. ( Frenz, MB; Lechowicz, I; Riphaus, A; Wehrmann, T, 2009) |
| "BACKGROUND The aim of the present study was to evaluate the effects of different doses of oxycodone during endoscopic injection sclerotherapy (EIS) for esophageal varices with painless sclerosing agents." | 4.02 | Different Doses of Oxycodone for Endoscopic Injection Sclerotherapy of Esophageal Varices. ( He, H; Quan, Z; Song, C; Yao, J; Zhou, C, 2021) |
| " However, adverse events (AEs) may occur more frequently in patients with cirrhosis due to altered MDZ metabolism." | 1.48 | Safety and effectiveness of midazolam for cirrhotic patients undergoing endoscopic variceal ligation. ( Jang, DK; Jo, HB; Kang, HW; Kim, JH; Koh, MS; Lee, JH; Lee, JK; Lim, YJ, 2018) |
| "Shock was more common in patients with variceal bleeding compared to those with non-variceal bleeding (12." | 1.43 | Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding. ( Eun, CS; Han, DS; Jeon, YC; Jeong, JY; Park, CH; Sohn, JH; Yoo, KS, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Yao, J | 1 |
| Song, C | 1 |
| Zhou, C | 1 |
| He, H | 2 |
| Quan, Z | 2 |
| Luo, C | 1 |
| Chi, P | 1 |
| Wang, L | 1 |
| Jo, HB | 1 |
| Lee, JK | 1 |
| Jang, DK | 1 |
| Kang, HW | 1 |
| Kim, JH | 1 |
| Lim, YJ | 1 |
| Koh, MS | 1 |
| Lee, JH | 1 |
| Watanabe, K | 1 |
| Hikichi, T | 1 |
| Takagi, T | 1 |
| Suzuki, R | 1 |
| Nakamura, J | 1 |
| Sugimoto, M | 1 |
| Kikuchi, H | 1 |
| Konno, N | 1 |
| Takasumi, M | 1 |
| Sato, Y | 1 |
| Hashimoto, M | 1 |
| Irie, H | 1 |
| Obara, K | 1 |
| Ohira, H | 1 |
| Kim, SI | 1 |
| Jin, YJ | 1 |
| Lee, SH | 1 |
| Lee, JW | 1 |
| Lee, DH | 1 |
| Lee, D | 1 |
| Park, CH | 1 |
| Han, DS | 1 |
| Jeong, JY | 1 |
| Eun, CS | 1 |
| Yoo, KS | 1 |
| Jeon, YC | 1 |
| Sohn, JH | 1 |
| Riphaus, A | 1 |
| Lechowicz, I | 1 |
| Frenz, MB | 1 |
| Wehrmann, T | 1 |
| Weston, BR | 1 |
| Chadalawada, V | 1 |
| Chalasani, N | 1 |
| Kwo, P | 1 |
| Overley, CA | 1 |
| Symms, M | 1 |
| Strahl, E | 1 |
| Rex, DK | 1 |
4 trials available for midazolam and Esophageal Varices
| Article | Year |
|---|---|
Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices.
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia; Body Mass Index; Double-Blind Method; Drug Therapy, Com | 2018 |
Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial.
Topics: Aged; Esophageal and Gastric Varices; Female; Hepatic Encephalopathy; Humans; Hypnotics and Sedative | 2018 |
Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study.
Topics: Aged; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Hepatic Encephalopathy; H | 2009 |
Nurse-administered propofol versus midazolam and meperidine for upper endoscopy in cirrhotic patients.
Topics: Aged; Ambulatory Care; Chronic Disease; Conscious Sedation; Dose-Response Relationship, Drug; Drug A | 2003 |
4 other studies available for midazolam and Esophageal Varices
| Article | Year |
|---|---|
Different Doses of Oxycodone for Endoscopic Injection Sclerotherapy of Esophageal Varices.
Topics: Adult; China; Dose-Response Relationship, Drug; Endoscopy; Esophageal and Gastric Varices; Female; G | 2021 |
Safety and effectiveness of midazolam for cirrhotic patients undergoing endoscopic variceal ligation.
Topics: Aged; Esophageal and Gastric Varices; Esophagoscopy; Female; Gastrointestinal Hemorrhage; Humans; Hy | 2018 |
Conscious Sedation Using Midazolam and Sequential Flumazenil in Cirrhotic Patients for Prophylactic Endoscopic Variceal Ligation.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Conscious Sedation; Esophageal and Gastric Varices; Esoph | 2015 |
Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding.
Topics: Adult; Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Cohort Studies; Comorbidity; Di | 2016 |