midazolam has been researched along with Endotoxin Shock in 11 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-five patients with septic shock were assigned to 3 groups (midazolam group, propofol group, and dexmedetomidine group) randomly." | 2.82 | [Clinical application of different sedation regimen in patients with septic shock]. ( Guo, F; Huang, HY; Tu, LY; Wang, Q; Yan, CY; Yu, X, 2016) |
| "Forty-three septic shock patients who were undergoing early goal-directed therapy resuscitated within 24 h were enrolled." | 2.80 | Propofol increases preload dependency in septic shock patients. ( Guo, F; Huang, Y; Li, Q; Liu, L; Peng, X; Qiu, H; Yang, Y; Yu, T, 2015) |
| "Midazolam and placebo were administered as bolus (0." | 2.70 | Midazolam sedation in mechanically ventilated newborns: a double blind randomized placebo controlled trial. ( Arya, V; Ramji, S, 2001) |
| "We reviewed 159 septic shock patients admitted to our intensive care unit (ICU) over a 40-month period to study the association between induction agent and clinical outcome, including vasopressor, inotrope, and steroid therapy." | 1.34 | Effect of induction agent on vasopressor and steroid use, and outcome in patients with septic shock. ( McKeown, DW; Ray, DC, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Penna, GL | 1 |
| Fialho, FM | 1 |
| Kurtz, P | 1 |
| Japiassú, AM | 1 |
| Kalichsztein, M | 1 |
| Nobre, G | 1 |
| Villela, NR | 1 |
| Bouskela, E | 1 |
| Selbst, SM | 1 |
| Yu, T | 2 |
| Peng, X | 2 |
| Liu, L | 1 |
| Li, Q | 1 |
| Huang, Y | 1 |
| Guo, F | 2 |
| Yang, Y | 2 |
| Qiu, H | 2 |
| Vistisen, ST | 1 |
| Wang, Q | 1 |
| Yan, CY | 1 |
| Huang, HY | 1 |
| Yu, X | 1 |
| Tu, LY | 1 |
| Kim, TY | 1 |
| Rhee, JE | 1 |
| Kim, KS | 1 |
| Cha, WC | 1 |
| Suh, GJ | 1 |
| Jung, SK | 1 |
| Ray, DC | 1 |
| McKeown, DW | 1 |
| Tobias, JD | 1 |
| Berkenbosch, JW | 1 |
| Arya, V | 1 |
| Ramji, S | 1 |
| Shelly, MP | 1 |
| Mendel, L | 1 |
| Park, GR | 1 |
3 trials available for midazolam and Endotoxin Shock
| Article | Year |
|---|---|
Propofol increases preload dependency in septic shock patients.
Topics: Aged; Aged, 80 and over; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Midazolam; Mid | 2015 |
[Clinical application of different sedation regimen in patients with septic shock].
Topics: Anesthesia; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive | 2016 |
Midazolam sedation in mechanically ventilated newborns: a double blind randomized placebo controlled trial.
Topics: Conscious Sedation; Double-Blind Method; Female; Humans; India; Infant, Newborn; Intensive Care Unit | 2001 |
8 other studies available for midazolam and Endotoxin Shock
| Article | Year |
|---|---|
Changing sedative infusion from propofol to midazolam improves sublingual microcirculatory perfusion in patients with septic shock.
Topics: Aged; Algorithms; APACHE; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Microcirculat | 2013 |
Pediatric emergency medicine: legal briefs.
Topics: Accidents, Traffic; Amputation, Surgical; Baseball; Brain Damage, Chronic; Child; Colon; Commitment | 2013 |
Propofol—or regression toward the mean—increases preload dependency.
Topics: Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Propofol; Shock, Septic | 2015 |
Response to letter to the editor on the article "Propofol increases preload dependency in septic shock patients".
Topics: Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Propofol; Shock, Septic | 2015 |
Etomidate should be used carefully for emergent endotracheal intubation in patients with septic shock.
Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Aged; Anesthetics, Intravenous; Etomidate; Female; H | 2008 |
Effect of induction agent on vasopressor and steroid use, and outcome in patients with septic shock.
Topics: Aged; Anesthetics, Intravenous; Etomidate; Female; Fentanyl; Humans; Intensive Care Units; Ketamine; | 2007 |
Tolerance during sedation in a pediatric ICU patient: effects on the BIS monitor.
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthetics; Anesthetics, Intravenous; Child; Down Syndrome; Drug | 2001 |
Failure of critically ill patients to metabolise midazolam.
Topics: Aged; Critical Care; Female; Humans; Hypnotics and Sedatives; Kinetics; Male; Midazolam; Middle Aged | 1987 |