midazolam has been researched along with Emphysema in 1 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Emphysema: A pathological accumulation of air in tissues or organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Serial blood samples were collected predose and up to 24 hours after each MDZ dose for pharmacokinetic (PK) evaluation." | 6.72 | Effect of R667, a novel emphysema agent, on the pharmacokinetics of midazolam in healthy men. ( Brennan, BJ; Brown, AB; Davies, BE; Gooden, C; Kolis, SJ; Rutman, O, 2006) |
| " Serial blood samples were collected predose and up to 24 hours after each MDZ dose for pharmacokinetic (PK) evaluation." | 2.72 | Effect of R667, a novel emphysema agent, on the pharmacokinetics of midazolam in healthy men. ( Brennan, BJ; Brown, AB; Davies, BE; Gooden, C; Kolis, SJ; Rutman, O, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brennan, BJ | 1 |
| Brown, AB | 1 |
| Kolis, SJ | 1 |
| Rutman, O | 1 |
| Gooden, C | 1 |
| Davies, BE | 1 |
1 trial available for midazolam and Emphysema
| Article | Year |
|---|---|
Effect of R667, a novel emphysema agent, on the pharmacokinetics of midazolam in healthy men.
Topics: Adult; Area Under Curve; Biotransformation; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P | 2006 |