Page last updated: 2024-10-31

midazolam and Emphysema

midazolam has been researched along with Emphysema in 1 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Emphysema: A pathological accumulation of air in tissues or organs.

Research Excerpts

ExcerptRelevanceReference
" Serial blood samples were collected predose and up to 24 hours after each MDZ dose for pharmacokinetic (PK) evaluation."6.72Effect of R667, a novel emphysema agent, on the pharmacokinetics of midazolam in healthy men. ( Brennan, BJ; Brown, AB; Davies, BE; Gooden, C; Kolis, SJ; Rutman, O, 2006)
" Serial blood samples were collected predose and up to 24 hours after each MDZ dose for pharmacokinetic (PK) evaluation."2.72Effect of R667, a novel emphysema agent, on the pharmacokinetics of midazolam in healthy men. ( Brennan, BJ; Brown, AB; Davies, BE; Gooden, C; Kolis, SJ; Rutman, O, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brennan, BJ1
Brown, AB1
Kolis, SJ1
Rutman, O1
Gooden, C1
Davies, BE1

Trials

1 trial available for midazolam and Emphysema

ArticleYear
Effect of R667, a novel emphysema agent, on the pharmacokinetics of midazolam in healthy men.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:2

    Topics: Adult; Area Under Curve; Biotransformation; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P

2006