midazolam has been researched along with Dystonia in 5 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| " She was managed successfully with midazolam infusion, calcium and vitamin D supplementation, and oral anti-dystonia drugs." | 3.85 | Status Dystonicus in a Child with Familial Idiopathic Hypoparathyroidism. ( Angurana, SK; Dayal, D; Ismail, J; Muralidharan, J, 2017) |
| " All our patients underwent continuous infusion of midazolam, in association with pimozide and trihexyphenidyl, which led to complete resolution of muscular spasms in two patients." | 3.78 | Management of status dystonicus in children. Cases report and review. ( Balestri, P; Grosso, S; Messina, M; Sacchini, M; Verrotti, A, 2012) |
| "This now includes progressive paroxysmal dystonia and adolescent-onset super-refractory myoclonic status epilepticus contributing to strikingly rapid and progressive cortical atrophy and death." | 2.58 | De Novo DNM1L Variant in a Teenager With Progressive Paroxysmal Dystonia and Lethal Super-refractory Myoclonic Status Epilepticus. ( Babovic-Vuksanovic, D; Boczek, NJ; Chan, DC; Cohen, AL; Fine, AL; Liu, R; Patterson, MC; Payne, ET; Renaud, DL; Ryan, CS; Schiltz, BM; Wirrell, EC, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ryan, CS | 1 |
| Fine, AL | 1 |
| Cohen, AL | 1 |
| Schiltz, BM | 1 |
| Renaud, DL | 1 |
| Wirrell, EC | 1 |
| Patterson, MC | 1 |
| Boczek, NJ | 1 |
| Liu, R | 1 |
| Babovic-Vuksanovic, D | 1 |
| Chan, DC | 1 |
| Payne, ET | 1 |
| Angurana, SK | 1 |
| Muralidharan, J | 1 |
| Dayal, D | 1 |
| Ismail, J | 1 |
| Grosso, S | 1 |
| Verrotti, A | 1 |
| Messina, M | 1 |
| Sacchini, M | 1 |
| Balestri, P | 1 |
| Knott, JC | 1 |
| Taylor, DM | 1 |
| Castle, DJ | 1 |
| Stolarek, IH | 1 |
| Ford, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oro-dispersible Olanzapine (Wafer) Versus Conventional Oral Haloperidol or Diazepam Tablets for the Management of Acute Agitation in the Accident and Emergency Department - a Multicentre Randomised Clinical Trial[NCT03246620] | Phase 4 | 12 participants (Actual) | Interventional | 2017-09-01 | Terminated (stopped due to The study was terminated prematurely due to difficulties in patient recruitment and associated potential for selection bias.) | ||
| Intramuscular Olanzapine Versus Haloperidol or Midazolam for the Management of Acute Agitation in the Emergency Department - a Multicentre Randomised Clinical Trial[NCT02380118] | Phase 4 | 167 participants (Actual) | Interventional | 2014-12-31 | Terminated (stopped due to Primary endpoint reached based on data projection from interim analysis.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for midazolam and Dystonia
| Article | Year |
|---|---|
De Novo DNM1L Variant in a Teenager With Progressive Paroxysmal Dystonia and Lethal Super-refractory Myoclonic Status Epilepticus.
Topics: Adolescent; Brain; Dynamins; Dystonia; Electroencephalography; GTP Phosphohydrolases; Humans; Hypnot | 2018 |
1 trial available for midazolam and Dystonia
| Article | Year |
|---|---|
Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department.
Topics: Adolescent; Adult; Aged; Apnea; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Dose-R | 2006 |
Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department.
Topics: Adolescent; Adult; Aged; Apnea; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Dose-R | 2006 |
Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department.
Topics: Adolescent; Adult; Aged; Apnea; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Dose-R | 2006 |
Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department.
Topics: Adolescent; Adult; Aged; Apnea; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Dose-R | 2006 |
3 other studies available for midazolam and Dystonia
| Article | Year |
|---|---|
Status Dystonicus in a Child with Familial Idiopathic Hypoparathyroidism.
Topics: Anti-Dyskinesia Agents; Calcium; Child; Drug Therapy, Combination; Dystonia; Female; Humans; Hypopar | 2017 |
Management of status dystonicus in children. Cases report and review.
Topics: Adolescent; Anti-Dyskinesia Agents; Baclofen; Brain; Case Management; Child; Cysts; Dystonia; Electr | 2012 |
Acute dystonia induced by midazolam and abolished by flumazenil.
Topics: Acute Disease; Adolescent; Dystonia; Flumazenil; Humans; Male; Midazolam | 1990 |