midazolam has been researched along with Dizzyness in 12 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Modafinil 200 mg was administered to the treatment group patients 1 h before sedation/analgesia." | 2.75 | Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills. ( Boesjes, H; Galvin, E; Hol, J; Klein, J; Ubben, JF; Verbrugge, SJ, 2010) |
| "In this randomized, double-blinded study, we compared the onset and recovery characteristics of an investigational benzodiazepine, Ro 48-6791 (when administered alone or combined with meperidine), a midazolam-meperidine combination for sedation during gastrointestinal (GI) endoscopic procedures." | 2.69 | Comparison of the sedation and recovery profiles of Ro 48-6791, a new benzodiazepine, and midazolam in combination with meperidine for outpatient endoscopic procedures. ( Gold, J; Gold, M; Tang, J; Wang, B; White, PF, 1999) |
| " We recorded adverse events during the endoscopic procedure and additionally retrieved questionnaires investigating subjective parameters 24 h after the endoscopic procedure." | 1.40 | Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices. ( Beck, S; Friedrich, K; Gotthardt, DN; Heil, FJ; Rex, DK; Scholl, SG; Sieg, A; Stremmel, W, 2014) |
| "The objectives of this study were to describe the type and frequency of postdischarge adverse events related to sedation for elective diagnostic imaging in children and to determine if any patient or drug characteristics were associated with such adverse events." | 1.38 | Postdischarge adverse events related to sedation for diagnostic imaging in children. ( Chen, X; Kaila, R; Kannikeswaran, N, 2012) |
| " The aim of this prospective observational audit was to evaluate our practice and report the occurrence of adverse events and behavioral reactions related to the use of ketamine, propofol, and midazolam combinations." | 1.35 | Adverse events and behavioral reactions related to ketamine based anesthesia for anorectal manometry in children. ( Dalal, PG; Seth, N; Somerville, N; Taylor, D, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, L | 1 |
| Wu, XW | 1 |
| Li, JY | 1 |
| Yan, ZW | 1 |
| Ze, HC | 1 |
| Liu, SY | 1 |
| Sieg, A | 1 |
| Beck, S | 1 |
| Scholl, SG | 1 |
| Heil, FJ | 1 |
| Gotthardt, DN | 1 |
| Stremmel, W | 1 |
| Rex, DK | 1 |
| Friedrich, K | 1 |
| Dilli, D | 1 |
| Dallar, Y | 1 |
| Sorgui, NH | 1 |
| Galvin, E | 1 |
| Boesjes, H | 1 |
| Hol, J | 1 |
| Ubben, JF | 1 |
| Klein, J | 1 |
| Verbrugge, SJ | 1 |
| Lee, JJ | 1 |
| Lee, JH | 1 |
| Hand, D | 1 |
| Averley, P | 1 |
| Lyne, J | 1 |
| Girdler, N | 1 |
| Kaila, R | 1 |
| Chen, X | 1 |
| Kannikeswaran, N | 1 |
| Dalal, PG | 1 |
| Taylor, D | 1 |
| Somerville, N | 1 |
| Seth, N | 1 |
| Donnelly, MB | 1 |
| Scott, WA | 1 |
| Daly, DS | 1 |
| Tang, J | 1 |
| Wang, B | 1 |
| White, PF | 1 |
| Gold, M | 1 |
| Gold, J | 1 |
| Short, TG | 1 |
| Galletly, DC | 1 |
| Rodrigo, MR | 1 |
| Cheung, LK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double Blind, Placebo Controlled Evaluation of Modafinil vs Placebo for the Treatment of General Anesthesia Related Delayed Emergence in Patients With the Diagnosis of Obstructive Sleep Apnea[NCT02494102] | Phase 4 | 105 participants (Actual) | Interventional | 2016-02-29 | Terminated | ||
| Use of Sevoflurane, Midazolam and Ketamine in Children for Dental Sedation Treatment: Occurrence of Adverse Events[NCT02284204] | Phase 2 | 27 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Length of time of above compared between groups (NCT02494102)
Timeframe: 24 hours
| Intervention | minutes (Mean) |
|---|---|
| Placebo | 53.5 |
| Modafinil | 61.0 |
Postanesthesia quality recovery scale (PQRS). Component and aggregate scoring on the scale. Measures physiology, nociceptive, emotional activities of daily living cognitive and overall patient perspective. The scale is dimensionless and the aggregate of all individually tested dimensions is scaled from 17-65. A higher value implies improved postanesthesia recovery. Mean difference was assessed in each patient and aggregated thus patients with no difference between pre- and post-operative scores were zeroed (received a zero score if the difference was zero). A negative value was associated with worse outcome. (NCT02494102)
Timeframe: baseline and 6 hours after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | -5.67 |
| Modafinil | -8.91 |
7 trials available for midazolam and Dizzyness
| Article | Year |
|---|---|
Intravenous ketamine plus midazolam vs. intravenous ketamine for sedation in lumbar puncture: a randomized controlled trial.
Topics: Adolescent; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Confidence Intervals; Dizzin | 2008 |
Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia Recovery Period; Anesthetics, Inha | 2010 |
Middle-ear surgery under sedation: comparison of midazolam alone or midazolam with remifentanil.
Topics: Adult; Anesthetics, Local; Anxiety; Conscious Sedation; Dizziness; Drug Therapy, Combination; Ear, M | 2011 |
Sedation for upper gastrointestinal endoscopy: a comparison of alfentanil-midazolam and meperidine-diazepam.
Topics: Age Factors; Alfentanil; Anesthesia Recovery Period; Apnea; Conscious Sedation; Diazepam; Dizziness; | 1994 |
Comparison of the sedation and recovery profiles of Ro 48-6791, a new benzodiazepine, and midazolam in combination with meperidine for outpatient endoscopic procedures.
Topics: Adjuvants, Anesthesia; Ambulatory Care; Analgesics, Opioid; Anesthesia Recovery Period; Anti-Anxiety | 1999 |
Residual psychomotor effects following reversal of midazolam sedation with flumazenil.
Topics: Adult; Affect; Dizziness; Flumazenil; Heart Rate; Humans; Hypnotics and Sedatives; Locomotion; Male; | 1989 |
Oral midazolam sedation in third molar surgery.
Topics: Administration, Oral; Adolescent; Adult; Anesthesia, Dental; Dizziness; Double-Blind Method; Female; | 1987 |
5 other studies available for midazolam and Dizzyness
| Article | Year |
|---|---|
[Effect of simulated navigation stimulation on the sedative action of midazolam in patients].
Topics: Adult; Dizziness; Humans; Hypnotics and Sedatives; Male; Midazolam; Naval Medicine; Young Adult | 2013 |
Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices.
Topics: Colonoscopy; Conscious Sedation; Dizziness; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 2014 |
Advanced paediatric conscious sedation: an alternative to dental general anaesthetic in the U.K.
Topics: Adolescent; Anesthesia, Dental; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intraven | 2011 |
Postdischarge adverse events related to sedation for diagnostic imaging in children.
Topics: Child; Child, Preschool; Dizziness; Female; Fentanyl; Follow-Up Studies; Humans; Hypnotics and Sedat | 2012 |
Adverse events and behavioral reactions related to ketamine based anesthesia for anorectal manometry in children.
Topics: Anal Canal; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, | 2008 |