midazolam has been researched along with Dissociation in 6 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously reported that ketamine has anxiolytic effects in patients with treatment-resistant generalized anxiety and social anxiety disorders." | 9.34 | Effects of ketamine in patients with treatment-refractory generalized anxiety and social anxiety disorders: Exploratory double-blind psychoactive-controlled replication study. ( Broughton, L; Glue, P; Le Nedelec, M; McNaughton, N; Medlicott, NJ; Neehoff, S; Sabadel, A; Shadli, S, 2020) |
| "Patients receiving ketamine for refractory depression and anxiety report dissociative symptoms in the first 60 min post-dose." | 9.24 | Effect of ketamine dose on self-rated dissociation in patients with treatment refractory anxiety disorders. ( Castle, C; Glue, P; Gray, A; Neehoff, S, 2017) |
| " Midazolam, S+ ketamine, placebo, or clonidine was used for the anesthesia." | 9.19 | Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: an RCT. ( Pretto, G; Silva, E; Westphal, GA, 2014) |
| " Memory for words presented during propofol and remifentanil general anesthesia was tested postoperatively by using a word-stem completion task in a process-dissociation procedure." | 7.75 | Analysis of Memory Formation during General Anesthesia (Propofol/Remifentanil) for Elective Surgery Using the Process-dissociation Procedure. ( Buchner, A; Degener, R; Hadzidiakos, D; Horn, N; Rehberg, B, 2009) |
| "We found that ketamine leads to significantly greater mystical-type effects (by Hood Mysticism Scale) and dissociation (by Clinician Administered Dissociative States Scale) compared to the active control." | 5.41 | Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial. ( Azhari, N; Dakwar, E; Haug, NA; Rothberg, RL, 2021) |
| "We previously reported that ketamine has anxiolytic effects in patients with treatment-resistant generalized anxiety and social anxiety disorders." | 5.34 | Effects of ketamine in patients with treatment-refractory generalized anxiety and social anxiety disorders: Exploratory double-blind psychoactive-controlled replication study. ( Broughton, L; Glue, P; Le Nedelec, M; McNaughton, N; Medlicott, NJ; Neehoff, S; Sabadel, A; Shadli, S, 2020) |
| " We found that ketamine leads to significantly greater acute mystical-type effects (by Hood Mysticism Scale: HMS), dissociation (by Clinician Administered Dissociative States Scale: CADSS), and near-death experience phenomena (by the Near-Death Experience Scale: NDES), relative to the active control midazolam." | 5.27 | A sub-set of psychoactive effects may be critical to the behavioral impact of ketamine on cocaine use disorder: Results from a randomized, controlled laboratory study. ( Dakwar, E; Foltin, RW; Hart, CL; Hu, MC; Levin, FR; Nunes, EV, 2018) |
| "Patients receiving ketamine for refractory depression and anxiety report dissociative symptoms in the first 60 min post-dose." | 5.24 | Effect of ketamine dose on self-rated dissociation in patients with treatment refractory anxiety disorders. ( Castle, C; Glue, P; Gray, A; Neehoff, S, 2017) |
| " Midazolam, S+ ketamine, placebo, or clonidine was used for the anesthesia." | 5.19 | Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: an RCT. ( Pretto, G; Silva, E; Westphal, GA, 2014) |
| " Memory for words presented during propofol and remifentanil general anesthesia was tested postoperatively by using a word-stem completion task in a process-dissociation procedure." | 3.75 | Analysis of Memory Formation during General Anesthesia (Propofol/Remifentanil) for Elective Surgery Using the Process-dissociation Procedure. ( Buchner, A; Degener, R; Hadzidiakos, D; Horn, N; Rehberg, B, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Glue, P | 2 |
| Neehoff, S | 2 |
| Sabadel, A | 1 |
| Broughton, L | 1 |
| Le Nedelec, M | 1 |
| Shadli, S | 1 |
| McNaughton, N | 1 |
| Medlicott, NJ | 1 |
| Rothberg, RL | 1 |
| Azhari, N | 1 |
| Haug, NA | 1 |
| Dakwar, E | 2 |
| Castle, C | 1 |
| Gray, A | 1 |
| Nunes, EV | 1 |
| Hart, CL | 1 |
| Hu, MC | 1 |
| Foltin, RW | 1 |
| Levin, FR | 1 |
| Pretto, G | 1 |
| Westphal, GA | 1 |
| Silva, E | 1 |
| Hadzidiakos, D | 1 |
| Horn, N | 1 |
| Degener, R | 1 |
| Buchner, A | 1 |
| Rehberg, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Music as a Potential Intervention to Improve Hemodynamic Tolerability of Repetitive Sub-Anesthetic IV Ketamine Infusions in Bipolar and Unipolar Depression: A Pilot Study[NCT04701866] | 32 participants (Actual) | Interventional | 2021-01-11 | Completed | |||
| Study of the Effect of Intraoperative Positive Messages on Postoperative Outcomes[NCT02765750] | 5 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to The primary investigator was transferred to another hospital) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for midazolam and Dissociation
| Article | Year |
|---|---|
Effects of ketamine in patients with treatment-refractory generalized anxiety and social anxiety disorders: Exploratory double-blind psychoactive-controlled replication study.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Blood Pressure; Brain-Derived Neuro | 2020 |
Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial.
Topics: Alcohol Drinking; Behavior, Addictive; Dissociative Disorders; Double-Blind Method; Female; Hallucin | 2021 |
Effect of ketamine dose on self-rated dissociation in patients with treatment refractory anxiety disorders.
Topics: Adolescent; Anxiety; Anxiety Disorders; Dissociative Disorders; Double-Blind Method; Humans; Ketamin | 2017 |
A sub-set of psychoactive effects may be critical to the behavioral impact of ketamine on cocaine use disorder: Results from a randomized, controlled laboratory study.
Topics: Cocaine-Related Disorders; Dissociative Disorders; Female; Hallucinogens; Hospitalization; Humans; K | 2018 |
Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: an RCT.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia; Anesthetics, Dissociative; Anti-Anxiety Age | 2014 |
1 other study available for midazolam and Dissociation
| Article | Year |
|---|---|
Analysis of Memory Formation during General Anesthesia (Propofol/Remifentanil) for Elective Surgery Using the Process-dissociation Procedure.
Topics: Adult; Aged; Algorithms; Anesthesia, General; Anesthetics, Intravenous; Dissociative Disorders; Elec | 2009 |