midazolam has been researched along with Diabetes Mellitus, Type 2 in 3 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gravel, S | 1 |
| Chiasson, JL | 1 |
| Turgeon, J | 1 |
| Grangeon, A | 1 |
| Michaud, V | 1 |
| Shi, R | 1 |
| Wu, J | 1 |
| Meng, C | 1 |
| Ma, B | 1 |
| Wang, T | 1 |
| Li, Y | 1 |
| Ma, Y | 1 |
| Rinehart, JB | 1 |
| Baker, B | 1 |
| Raphael, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Type 2 Diabetes on CYP450s Activities; Intersubject Variability in Drug Metabolism.[NCT02291666] | Phase 4 | 73 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for midazolam and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Modulation of CYP450 Activities in Patients With Type 2 Diabetes.
Topics: Adult; Aged; Bupropion; Caffeine; Case-Control Studies; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cyto | 2019 |
Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.
Topics: Animals; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucuron | 2016 |
Postoperative global amnesia reversed with flumazenil.
Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desfluran | 2012 |