Page last updated: 2024-10-31

midazolam and Developmental Disabilities

midazolam has been researched along with Developmental Disabilities in 6 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Developmental Disabilities: Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)

Research Excerpts

ExcerptRelevanceReference
"All had developmental delay (66."5.62The Use of Oral Midazolam to Facilitate the Ophthalmic Examination of Children with Autism and Developmental Disorders. ( Comer, G; Flanagan, O; McBride, GR; Stephenson, KAJ, 2021)
"All had developmental delay (66."1.62The Use of Oral Midazolam to Facilitate the Ophthalmic Examination of Children with Autism and Developmental Disorders. ( Comer, G; Flanagan, O; McBride, GR; Stephenson, KAJ, 2021)
" Medication dosing generally followed standard dosing guidelines with very few exceptions."1.51Seizure Rescue Medication Use among US Pediatric Epilepsy Providers: A Survey of the Pediatric Epilepsy Research Consortium. ( Payne, E; Wallace, A; Wirrell, E, 2019)
"Midazolam exposure was associated with macro- and microstructural alterations in hippocampal development and poorer outcomes consistent with hippocampal dysmaturation."1.43Midazolam dose correlates with abnormal hippocampal growth and neurodevelopmental outcome in preterm infants. ( Chakravarty, MM; Chau, V; Dodbiba, L; Duerden, EG; Grunau, RE; Guo, T; Miller, SP; Poskitt, KJ; Synnes, A, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Asada, R1
Hori, H1
Iida, H1
Kawasaki, H1
McBride, GR1
Stephenson, KAJ1
Comer, G1
Flanagan, O1
Xu, J1
Mathena, RP1
Singh, S1
Kim, J1
Long, JJ1
Li, Q1
Junn, S1
Blaize, E1
Mintz, CD1
Wallace, A1
Wirrell, E1
Payne, E1
Duerden, EG1
Guo, T1
Dodbiba, L1
Chakravarty, MM1
Chau, V1
Poskitt, KJ1
Synnes, A1
Grunau, RE1
Miller, SP1
Casado, AI1
Ruiz, J1
Oro, J1
Martínez, C1
Fernández, I1
Oliva, P1

Other Studies

6 other studies available for midazolam and Developmental Disabilities

ArticleYear
Benzodiazepine withdrawal catatonia after discontinuing midazolam in young patient with intellectual developmental disorder: A case report.
    Asian journal of psychiatry, 2023, Volume: 89

    Topics: Adult; Benzodiazepines; Catatonia; Developmental Disabilities; Humans; Intellectual Disability; Male

2023
The Use of Oral Midazolam to Facilitate the Ophthalmic Examination of Children with Autism and Developmental Disorders.
    Journal of autism and developmental disorders, 2021, Volume: 51, Issue:5

    Topics: Administration, Oral; Autistic Disorder; Child; Child, Preschool; Cohort Studies; Conscious Sedation

2021
Early Developmental Exposure to Repetitive Long Duration of Midazolam Sedation Causes Behavioral and Synaptic Alterations in a Rodent Model of Neurodevelopment.
    Journal of neurosurgical anesthesiology, 2019, Volume: 31, Issue:1

    Topics: Aging; Animals; Behavior, Animal; Cells, Cultured; Conscious Sedation; Dentate Gyrus; Developmental

2019
Seizure Rescue Medication Use among US Pediatric Epilepsy Providers: A Survey of the Pediatric Epilepsy Research Consortium.
    The Journal of pediatrics, 2019, Volume: 212

    Topics: Administration, Intranasal; Administration, Oral; Administration, Rectal; Adolescent; Age Factors; A

2019
Midazolam dose correlates with abnormal hippocampal growth and neurodevelopmental outcome in preterm infants.
    Annals of neurology, 2016, Volume: 79, Issue:4

    Topics: Child Development; Developmental Disabilities; Dose-Response Relationship, Drug; Female; Follow-Up S

2016
Anaesthetic management in a case of Kabuki syndrome.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:2

    Topics: Abnormalities, Multiple; Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; A

2004