Page last updated: 2024-10-31

midazolam and Dental Caries

midazolam has been researched along with Dental Caries in 8 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Dental Caries: Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.

Research Excerpts

ExcerptRelevanceReference
"This paper demonstrates how oral midazolam can be employed as an alternative method of behaviour management to general anaesthesia for the dental treatment of people with learning disabilities."7.70Oral midazolam for adults with learning disabilities. ( Boyle, CA; Fleming, GJ; Manley, MC, 2000)
"5 mg·kg -1 midazolam oral liquid for the treatment of dental caries was 1."5.69Intranasal esketamine combined with oral midazolam provides adequate sedation for outpatient pediatric dental procedures: a prospective cohort study. ( Chen, S; Chen, Z; Liao, J; Ran, H; Wang, J; Yu, C; Zeng, J; Zhao, N, 2023)
"This paper demonstrates how oral midazolam can be employed as an alternative method of behaviour management to general anaesthesia for the dental treatment of people with learning disabilities."3.70Oral midazolam for adults with learning disabilities. ( Boyle, CA; Fleming, GJ; Manley, MC, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Wang, J1
Zeng, J1
Zhao, N1
Chen, S1
Chen, Z1
Liao, J1
Ran, H1
Yu, C1
Yamamoto, T1
Miyazawa, N1
Yamamoto, S1
Kawahara, H1
Kim, BW1
Peskin, RM1
Antunes, DE2
Viana, KA1
Costa, PS2
Costa, LR2
Xia, B1
Liu, KY1
Wang, CL1
Sun, LJ1
Ge, LH1
Moreira, TA1
Jesus-França, CM1
Gomes, HS1
Neto, OA1
Wan, K1
Jing, Q1
Zhao, JZ1
Boyle, CA1
Manley, MC1
Fleming, GJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Controlled Trial of Oral Sedatives for Moderate Sedation in Young Children[NCT00902395]Phase 441 participants (Actual)Interventional2008-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for midazolam and Dental Caries

ArticleYear
Intranasal esketamine combined with oral midazolam provides adequate sedation for outpatient pediatric dental procedures: a prospective cohort study.
    International journal of surgery (London, England), 2023, Jul-01, Volume: 109, Issue:7

    Topics: Anesthesia; Child; Dental Caries; Humans; Hypnotics and Sedatives; Midazolam; Outpatients; Prospecti

2023
Moderate sedation helps improve future behavior in pediatric dental patients - a prospective study.
    Brazilian oral research, 2016, Oct-24, Volume: 30, Issue:1

    Topics: Age Factors; Analysis of Variance; Anesthesia, General; Anesthetics, Dissociative; Child Behavior; C

2016
[Clinical evaluation of oral midazolam sedation for dental treatment in children].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2010, Feb-18, Volume: 42, Issue:1

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Conscious Sedation; Crowns; Dental Caries

2010
Combined oral midazolam-ketamine better than midazolam alone for sedation of young children: a randomized controlled trial.
    International journal of paediatric dentistry, 2013, Volume: 23, Issue:3

    Topics: Administration, Oral; Anesthesia, Dental; Child Behavior; Child, Preschool; Conscious Sedation; Coop

2013
Evaluation of oral midazolam as conscious sedation for pediatric patients in oral restoration.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2006, Volume: 21, Issue:3

    Topics: Administration, Oral; Anti-Anxiety Agents; Blood Pressure; Child; Child Behavior; Child, Preschool;

2006

Other Studies

3 other studies available for midazolam and Dental Caries

ArticleYear
Anesthetic Management in Mitochondrial Encephalomyopathy: A Case Report.
    Anesthesia progress, 2017,Winter, Volume: 64, Issue:4

    Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia, General; Dental Caries; Entropion; Humans; Male; Mida

2017
Dexmedetomidine, ketamine, and midazolam for oral rehabilitation: a case report.
    Anesthesia progress, 2015,Spring, Volume: 62, Issue:1

    Topics: Adult; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Dissociative; Ane

2015
Oral midazolam for adults with learning disabilities.
    Dental update, 2000, Volume: 27, Issue:4

    Topics: Administration, Oral; Adult; Anesthesia, Dental; Behavior Therapy; Conscious Sedation; Dental Calcul

2000