Page last updated: 2024-10-31

midazolam and Deficiency, Mental

midazolam has been researched along with Deficiency, Mental in 18 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effect of N2O inhalation and oral midazolam sedation on uncooperative patients with intellectual disability in pediatric dentistry."7.81[Evaluation of N2O inhalation and oral midazolam conscious sedation in pediatric dentistry of children with intellectual disability]. ( Li, XF; Tian, XH; Yang, YZ, 2015)
"The use of midazolam for dental care in patients with intellectual disability is poorly documented."5.17Conscious sedation procedures using intravenous midazolam for dental care in patients with different cognitive profiles: a prospective study of effectiveness and safety. ( Collado, V; Faulks, D; Hennequin, M; Nicolas, E, 2013)
"To evaluate the effect of N2O inhalation and oral midazolam sedation on uncooperative patients with intellectual disability in pediatric dentistry."3.81[Evaluation of N2O inhalation and oral midazolam conscious sedation in pediatric dentistry of children with intellectual disability]. ( Li, XF; Tian, XH; Yang, YZ, 2015)
" A significant odds ratio related to decreased SpO2 was observed for age, sex, midazolam and propofol levels, concurrent use of nitrous oxide, cerebral palsy, Down syndrome, and mental retardation."3.79Risk factors with intravenous sedation for patients with disabilities. ( Fukayama, H; Ishikawa, M; Jinno, S; Kohase, H; Kunimori, H; Miwa, Z; Nakamura, Z; Okumura, H; Shimoyama, K; Tamaki, Y; Yoshikawa, F, 2013)
"Midazolam was used in approximately 47% in the MC group."1.40Survey on choice of intravenous sedative agent at department of dental anesthesiology, Tokyo Dental College Chiba Hospital between 2010 and 2011. ( Ichinohe, T; Kasahara, M; Matsuki, Y; Matsuura, N; Okamura, T; Shiozaki, K, 2014)
"Midazolam has shown in this follow-up to be an effective and safe drug for premedication of infants in the stressed dental situation."1.31Rectal administration of midazolam for conscious sedation of uncooperative children in need of dental treatment. ( Lindh-Strömberg, U, 2001)
"Midazolam was administered to three mentally retarded patients with acute and refractory aggressivity and violence."1.28Midazolam for aggressivity and violence in three mentally retarded patients. ( Bond, WS; Kurtz, MB; Mandos, LA, 1989)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's3 (16.67)18.2507
2000's4 (22.22)29.6817
2010's7 (38.89)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Oda, Y1
Yoshida, K1
Kawano, R1
Yoshinaka, T1
Oda, A1
Takahashi, T1
Oue, K1
Mukai, A1
Irifune, M1
Okada, Y1
Asada, R1
Hori, H1
Iida, H1
Kawasaki, H1
Frohlich, J1
Reiter, LT1
Saravanapandian, V1
DiStefano, C1
Huberty, S1
Hyde, C1
Chamberlain, S1
Bearden, CE1
Golshani, P1
Irimia, A1
Olsen, RW1
Hipp, JF1
Jeste, SS1
Collado, V1
Faulks, D1
Nicolas, E1
Hennequin, M1
Yoshikawa, F1
Tamaki, Y1
Okumura, H1
Miwa, Z1
Ishikawa, M1
Shimoyama, K1
Nakamura, Z1
Kunimori, H1
Jinno, S1
Kohase, H1
Fukayama, H1
Matsuki, Y1
Okamura, T1
Shiozaki, K1
Matsuura, N1
Kasahara, M1
Ichinohe, T1
Tian, XH1
Yang, YZ1
Li, XF1
Bakan, M1
Idin, K1
Karaaslan, K1
Ozturk, E1
Horacek, J1
Palenicek, T1
Malek, J1
Scigel, V1
Kurzova, A1
Hess, L1
Casado, AI1
Ruiz, J1
Oro, J1
Martínez, C1
Fernández, I1
Oliva, P1
Gooden, CK1
Pate, VA1
Kavee, R1
Canbay, O1
Kose, EA1
Celebi, N1
Karagoz, AH1
Ozgen, S1
Fukuta, O1
Braham, RL1
Yanase, H1
Atsumi, N1
Kurosu, K1
van der Bijl, P1
Roelofse, JA1
Lindh-Strömberg, U1
Tuel, DC1
Weis, FR1
Valentin, AH1
Foitzik, C1
Bond, WS1
Mandos, LA1
Kurtz, MB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Conscious Sedation With Midazolam in Dentally Anxious Patients: Effect of the Administration Route (Oral Versus Intravenous Administration)[NCT01874717]Phase 3131 participants (Actual)Interventional2005-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for midazolam and Deficiency, Mental

ArticleYear
Mechanisms underlying the EEG biomarker in Dup15q syndrome.
    Molecular autism, 2019, Volume: 10

    Topics: Adult; Biomarkers; Child; Chromosome Aberrations; Chromosomes, Human, Pair 15; Cohort Studies; Elect

2019
Conscious sedation procedures using intravenous midazolam for dental care in patients with different cognitive profiles: a prospective study of effectiveness and safety.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthetics, Intravenous; Anxiety Disorders; Child; Cog

2013
The influence of clonidine on oral ketamine-midazolam premedication in intellectually disabled patients indicated for dental procedures: double-blind comparison of two sedation regimes.
    Neuro endocrinology letters, 2012, Volume: 33, Issue:4

    Topics: Adult; Anesthesia, Dental; Clinical Protocols; Clonidine; Dental Care for Disabled; Disabled Persons

2012

Other Studies

15 other studies available for midazolam and Deficiency, Mental

ArticleYear
Effects of antipsychotics on intravenous sedation with midazolam and propofol during dental treatment for patients with intellectual disabilities.
    Journal of intellectual disability research : JIDR, 2022, Volume: 66, Issue:4

    Topics: Antipsychotic Agents; Conscious Sedation; Dental Care; Humans; Hypnotics and Sedatives; Intellectual

2022
Benzodiazepine withdrawal catatonia after discontinuing midazolam in young patient with intellectual developmental disorder: A case report.
    Asian journal of psychiatry, 2023, Volume: 89

    Topics: Adult; Benzodiazepines; Catatonia; Developmental Disabilities; Humans; Intellectual Disability; Male

2023
Risk factors with intravenous sedation for patients with disabilities.
    Anesthesia progress, 2013,Winter, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Dental; Anesthes

2013
Survey on choice of intravenous sedative agent at department of dental anesthesiology, Tokyo Dental College Chiba Hospital between 2010 and 2011.
    The Bulletin of Tokyo Dental College, 2014, Volume: 55, Issue:3

    Topics: Administration, Intravenous; Adult; Aged; Anesthesia, Dental; Anesthetics, Intravenous; Cerebral Pal

2014
[Evaluation of N2O inhalation and oral midazolam conscious sedation in pediatric dentistry of children with intellectual disability].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2015, Volume: 24, Issue:3

    Topics: Administration, Inhalation; Child; Conscious Sedation; Humans; Intellectual Disability; Midazolam; N

2015
Anaesthesia and orphan disease: anaesthetic management of a child with Pena-Shokeir syndrome.
    European journal of anaesthesiology, 2012, Volume: 29, Issue:12

    Topics: Alopecia; Anesthesia; Anesthetics; Child; Cleft Palate; Craniofacial Abnormalities; Epilepsy; Female

2012
Anaesthetic management in a case of Kabuki syndrome.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:2

    Topics: Abnormalities, Multiple; Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; A

2004
Anesthetic management of a child with Aicardi syndrome.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:2

    Topics: Abnormalities, Multiple; Adjuvants, Anesthesia; Agenesis of Corpus Callosum; Anesthesia; Anesthetics

2005
Anesthesia for congenital insensitivity to pain with anhidrosis.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:2

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Debridement; Fentanyl

2007
The sedative effect of intranasal midazolam administration in the dental treatment of patients with mental disabilities. Part 1. The effect of a 0.2 mg/kg dose.
    The Journal of clinical pediatric dentistry, 1993,Summer, Volume: 17, Issue:4

    Topics: Administration, Intranasal; Adolescent; Adult; Analysis of Variance; Anesthesia, Dental; Autistic Di

1993
Propofol and midazolam for conscious sedation in a mentally retarded dental patient.
    Anesthesia progress, 1992, Volume: 39, Issue:1-2

    Topics: Adult; Conscious Sedation; Dental Care for Disabled; Female; Heart Defects, Congenital; Humans; Infu

1992
Rectal administration of midazolam for conscious sedation of uncooperative children in need of dental treatment.
    Swedish dental journal, 2001, Volume: 25, Issue:3

    Topics: Administration, Rectal; Anesthesia, Dental; Anti-Anxiety Agents; Child; Child Behavior; Child, Presc

2001
Oral midazolam for a mentally retarded patient.
    Anesthesiology, 1990, Volume: 72, Issue:1

    Topics: Administration, Oral; Adolescent; Humans; Intellectual Disability; Male; Midazolam; Preanesthetic Me

1990
[Concepts for periodontal treatment for mentally retarded children].
    Die Quintessenz, 1989, Volume: 40, Issue:11

    Topics: Anesthesia, Dental; Appointments and Schedules; Child; Dental Care for Disabled; Humans; Intellectua

1989
Midazolam for aggressivity and violence in three mentally retarded patients.
    The American journal of psychiatry, 1989, Volume: 146, Issue:7

    Topics: Adolescent; Adult; Aggression; Female; Humans; Intellectual Disability; Male; Midazolam; Violence

1989