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midazolam and Cystic Fibrosis

midazolam has been researched along with Cystic Fibrosis in 3 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group."9.08[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998)
"To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group."5.08[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998)
"There is an increase in sedative drug requirement with time for both midazolam and fentanyl after transplantation, which is significantly higher in patients with cystic fibrosis."3.73Sedative drug requirements during bronchoscopy are higher in cystic fibrosis after lung transplantation. ( Aboyoun, C; Chhajed, PN; Chhajed, TP; Glanville, AR; Harrison, GA; Leuppi, JD; Malouf, MA; Tamm, M, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chhajed, PN1
Aboyoun, C1
Chhajed, TP1
Malouf, MA1
Harrison, GA1
Tamm, M1
Leuppi, JD1
Glanville, AR1
Garcia, J1
Roure, P1
Hayem, C1
Dupont, D1
McLeod, DH1
Gaukroger, PB1

Trials

1 trial available for midazolam and Cystic Fibrosis

ArticleYear
[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination].
    Revue des maladies respiratoires, 1998, Volume: 15, Issue:2

    Topics: Adjuvants, Anesthesia; Administration, Rectal; Anesthesia, Local; Anesthetics, Inhalation; Anestheti

1998

Other Studies

2 other studies available for midazolam and Cystic Fibrosis

ArticleYear
Sedative drug requirements during bronchoscopy are higher in cystic fibrosis after lung transplantation.
    Transplantation, 2005, Oct-27, Volume: 80, Issue:8

    Topics: Adolescent; Adult; Bronchoscopy; Cystic Fibrosis; Female; Fentanyl; Humans; Hypnotics and Sedatives;

2005
Anaesthetic management for pancreatic stimulation test.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:2

    Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthesia, Rectal; Child; Cystic Fibrosis; Humans; Mi

1992