Page last updated: 2024-10-31

midazolam and Cyanosis

midazolam has been researched along with Cyanosis in 6 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Cyanosis: A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.

Research Excerpts

ExcerptRelevanceReference
"Methemoglobinemia (MetHb) after exposure to benzocaine (BZC) has been reported for more than 50 years, however the pathophysiologic mechanism has not been previously established."3.80Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure. ( Casavant, MJ; Gerona, RR; Ho, RY; Russell, JL; Spiller, HA, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spiller, HA1
Russell, JL1
Casavant, MJ1
Ho, RY1
Gerona, RR1
Montero, JV1
Nieto, EM1
Vallejo, IR1
Montero, SV1
Okazaki, J1
Isono, S1
Hasegawa, H1
Sakai, M1
Nagase, Y1
Nishino, T1
Chauhan, S1
Ingole, P1
Kale, S1
Kiran, U1
Alswang, M1
Friesen, RH1
Bangert, P1
Levine, MF1
Hartley, EJ1
Macpherson, BA1
Burrows, FA1
Lerman, J1

Trials

2 trials available for midazolam and Cyanosis

ArticleYear
Effect of preanesthetic medication on carbon dioxide tension in children with congenital heart disease.
    Journal of cardiothoracic and vascular anesthesia, 1994, Volume: 8, Issue:4

    Topics: Blood Gas Monitoring, Transcutaneous; Blood Pressure; Carbon Dioxide; Child; Child, Preschool; Consc

1994
Oral midazolam premedication for children with congenital cyanotic heart disease undergoing cardiac surgery: a comparative study.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:10

    Topics: Administration, Oral; Administration, Rectal; Anxiety, Separation; Atropine; Awareness; Child; Child

1993

Other Studies

4 other studies available for midazolam and Cyanosis

ArticleYear
Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure.
    Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:9

    Topics: 4-Aminobenzoic Acid; Acetaminophen; Administration, Topical; Benzocaine; Bupivacaine; Child; Cyanosi

2014
Intranasal midazolam for the emergency management of hypercyanotic spells in tetralogy of Fallot.
    Pediatric emergency care, 2015, Volume: 31, Issue:4

    Topics: Administration, Intranasal; Cyanosis; Emergency Service, Hospital; Humans; Hypnotics and Sedatives;

2015
Quantitative assessment of tracheal collapsibility in infants with tracheomalacia.
    American journal of respiratory and critical care medicine, 2004, Oct-01, Volume: 170, Issue:7

    Topics: Airway Resistance; Anesthesia, General; Body Weight; Bronchoscopy; Case-Control Studies; Compliance;

2004
Correlation of BIS with Tet spells.
    Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:5

    Topics: Analgesics; Anti-Anxiety Agents; Child; Cyanosis; Electroencephalography; Heart Defects, Congenital;

2004