Page last updated: 2024-10-31

midazolam and Costello Syndrome

midazolam has been researched along with Costello Syndrome in 1 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Costello Syndrome: Rare congenital disorder with multiple anomalies including: characteristic dysmorphic craniofacial features, musculoskeletal abnormalities, neurocognitive delay, and high prevalence of cancer. Germline mutations in H-Ras protein can cause Costello syndrome. Costello syndrome shows early phenotypic overlap with other disorders that involve MAP KINASE SIGNALING SYSTEM (e.g., NOONAN SYNDROME and cardiofaciocutaneous syndrome).

Research Excerpts

ExcerptRelevanceReference
"Costello syndrome is a rare genetic disorder characterized by mental and growth retardation and distinctive coarse facies."1.51Anesthetic Management in an Adult Patient With Costello Syndrome: A Case Report. ( Hashimoto, A; Imamachi, N; Saito, Y; Ugata, K, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ugata, K1
Imamachi, N1
Hashimoto, A1
Saito, Y1

Other Studies

1 other study available for midazolam and Costello Syndrome

ArticleYear
Anesthetic Management in an Adult Patient With Costello Syndrome: A Case Report.
    A&A practice, 2019, Jul-15, Volume: 13, Issue:2

    Topics: Adult; Anesthetics, General; Costello Syndrome; Female; Fentanyl; Humans; Midazolam; Preoperative Ca

2019