midazolam has been researched along with Coronary Disease in 29 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "003 mg/kg fentanyl the patients received the induction agent in the above-mentioned dosage within 40 s followed by 0." | 6.66 | [Comparative hemodynamic study of anesthesia induction with propofol (Diprivan), thiopental, methohexital, etomidate and midazolam in patients with coronary disease]. ( Boldt, J; Börner, U; Hempelmann, G; Kling, D; Laubenthal, H, 1987) |
| "Demographic data, hemodynamic variables, sedation and anxiety scores, amnesia, patient and cardiologist satisfaction, and adverse effects were evaluated and compared among coronary angiography patients taking midazolam, midazolam and fentanyl, or placebo before the procedure." | 5.09 | Comparison of midazolam with or without fentanyl for conscious sedation and hemodynamics in coronary angiography. ( Aykent, R; Baris, S; Karakaya, D; Kirdar, K; Sagkan, O; Tür, A, 2001) |
| "We studied the hemodynamic interaction between midazolam and alfentanil during induction of anaesthesia in 27 patients with coronary heart disease." | 5.06 | [Hemodynamic interaction between midazolam and alfentanil in coronary patients]. ( Schwinn, W; Skarvan, K, 1986) |
| "It is hypothesized that because of its potential to increase coronary flow and simultaneously decrease myocardial performance and O2 consumption, midazolam would minimize regional metabolic impairment during myocardial ischemia." | 3.69 | Midazolam's effects on myocardial load and coronary perfusion: reduced regional O2 consumption and lactate production during ischemia in dogs. ( Rush, W; Sidi, A, 1994) |
| " Anesthesia was maintained with fentanyl and midazolam." | 3.69 | [The anesthetic management of patients in chronic renal failure for coronary artery bypass surgery without cardiopulmonary bypass]. ( Gotou, K; Hashimoto, Y; Kimura, F; Kimura, N; Wakayama, S, 1997) |
| "Midazolam was associated with a greater sedative and cardiovascular effect, whereas for diazepam these effects were less intense." | 2.73 | Sedative and cardiovascular effects of midazolam and diazepam alone or combined with clonidine in patients undergoing hemodynamic studies for suspected coronary artery disease. ( Carvalho, HG; Modolo, NS; Nascimento, Jdos S; Santos, KP; Silva, RC, 2007) |
| "Pretreatment with midazolam seemed to protect the patient from this undesirable reaction." | 2.66 | [Low-dose midazolam. Effect on the induction doses of fentanyl and on hemodynamics in the coronary patient]. ( Brasey, AM; Burgener, MH; Morel, D; Neidhart, P, 1988) |
| "003 mg/kg fentanyl the patients received the induction agent in the above-mentioned dosage within 40 s followed by 0." | 2.66 | [Comparative hemodynamic study of anesthesia induction with propofol (Diprivan), thiopental, methohexital, etomidate and midazolam in patients with coronary disease]. ( Boldt, J; Börner, U; Hempelmann, G; Kling, D; Laubenthal, H, 1987) |
| "Midazolam is a suitable alternative to diazepam as part of an intravenous induction regimen in patients with ischaemic heart disease." | 1.27 | Haemodynamic changes during induction of anaesthesia with midazolam and diazepam (Valium) in patients undergoing coronary artery bypass surgery. ( Carson, IW; Clarke, RS; Dundee, JW; Kawar, P; Lyons, SM, 1985) |
| "Midazolam appears to be a valuable alternative to conventional induction agents without adverse effects on the cardiovascular system." | 1.26 | Haemodynamic responses to induction of anaesthesia using midazolam in cardiac surgical patients. ( Hess, W; Schulte-Sasse, U; Tarnow, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (34.48) | 18.7374 |
| 1990's | 13 (44.83) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| But, AK | 1 |
| Durmus, M | 1 |
| Toprak, HI | 1 |
| Ozturk, E | 1 |
| Demirbilek, S | 1 |
| Ersoy, MO | 1 |
| Behny, LR | 1 |
| Cillo, JE | 1 |
| Finn, R | 1 |
| Venkatesh, BG | 1 |
| Mehta, Y | 1 |
| Kumar, A | 1 |
| Trehan, N | 1 |
| Nascimento, Jdos S | 1 |
| Modolo, NS | 1 |
| Silva, RC | 1 |
| Santos, KP | 1 |
| Carvalho, HG | 1 |
| Massaut, J | 1 |
| d'Hollander, A | 1 |
| Barvais, L | 1 |
| Dubois-Primo, J | 1 |
| Schulte-Sasse, U | 1 |
| Hess, W | 1 |
| Tarnow, J | 1 |
| Samuelson, PN | 1 |
| Reves, JG | 1 |
| Kouchoukos, NT | 1 |
| Smith, LR | 2 |
| Dole, KM | 1 |
| Messina, AG | 1 |
| Paranicas, M | 1 |
| Yao, FS | 1 |
| Illner, P | 1 |
| Roman, MJ | 1 |
| Saba, PS | 1 |
| Devereux, RB | 1 |
| Sidi, A | 1 |
| Rush, W | 1 |
| Higgins, TL | 1 |
| Yared, JP | 1 |
| Estafanous, FG | 1 |
| Coyle, JP | 1 |
| Ko, HK | 1 |
| Goodale, DB | 1 |
| Thorelius, J | 2 |
| Wesslén, O | 2 |
| Björkman, JA | 1 |
| Ekroth, R | 2 |
| Joachimsson, PO | 2 |
| Ronquist, G | 1 |
| Tydén, H | 2 |
| Lischke, V | 1 |
| Wilke, HJ | 1 |
| Probst, S | 1 |
| Behne, M | 1 |
| Kessler, P | 1 |
| Spahn, DR | 1 |
| Hu, WC | 1 |
| Leone, BJ | 1 |
| Hallhagen, S | 1 |
| von der Linden, J | 1 |
| Thrush, DN | 1 |
| Gotou, K | 1 |
| Kimura, F | 1 |
| Kimura, N | 1 |
| Hashimoto, Y | 1 |
| Wakayama, S | 1 |
| Tritapepe, L | 1 |
| Baris, S | 1 |
| Karakaya, D | 1 |
| Aykent, R | 1 |
| Kirdar, K | 1 |
| Sagkan, O | 1 |
| Tür, A | 1 |
| Colson, P | 1 |
| Médioni, P | 1 |
| Saussine, M | 1 |
| Séguin, JR | 1 |
| Cuchet, D | 1 |
| Grolleau, D | 1 |
| Chaptal, PA | 1 |
| Roquefeuil, B | 1 |
| Vrána, M | 1 |
| Fejfar, Z | 1 |
| Hess, L | 1 |
| Blazek, Z | 1 |
| Gordon, AR | 1 |
| O'Connor, JP | 1 |
| Ralley, FE | 1 |
| Ramsay, JG | 1 |
| Malcolm, I | 1 |
| Raza, SM | 1 |
| Masters, RW | 1 |
| Zsigmond, EK | 1 |
| Kawar, P | 1 |
| Carson, IW | 1 |
| Clarke, RS | 1 |
| Dundee, JW | 1 |
| Lyons, SM | 1 |
| Marty, J | 1 |
| Nitenberg, A | 1 |
| Blanchet, F | 1 |
| Zouioueche, S | 1 |
| Desmonts, JM | 1 |
| Skarvan, K | 1 |
| Schwinn, W | 1 |
| Neidhart, P | 1 |
| Burgener, MH | 1 |
| Brasey, AM | 1 |
| Morel, D | 1 |
| Kling, D | 1 |
| Laubenthal, H | 1 |
| Börner, U | 1 |
| Boldt, J | 1 |
| Hempelmann, G | 1 |
| Lepage, JY | 1 |
| Blanloeil, Y | 1 |
| Pinaud, M | 1 |
| Helias, J | 1 |
| Auneau, C | 1 |
| Cozian, A | 1 |
| Souron, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Randomised Controled Trial: Comparison of Volatile Anaesthetics Sevoflurane vs. Isoflurane for Low-Flow General Anaesthesia for Abdominal Surgery[NCT00521612] | 82 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for midazolam and Coronary Disease
| Article | Year |
|---|---|
Off-pump coronary artery bypass grafting: a case report.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 2006 |
12 trials available for midazolam and Coronary Disease
| Article | Year |
|---|---|
Hemodynamic, hepatorenal, and postoperative effects of desflurane-fentanyl and midazolam-fentanyl anesthesia in coronary artery bypass surgery.
Topics: Adult; Anesthetics, Combined; Anesthetics, General; Biomarkers; Coronary Artery Bypass; Coronary Dis | 2005 |
Sedative and cardiovascular effects of midazolam and diazepam alone or combined with clonidine in patients undergoing hemodynamic studies for suspected coronary artery disease.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Analysis of Variance; Blood P | 2007 |
Propofol versus midazolam for intensive care unit sedation after coronary artery bypass grafting.
Topics: Adult; Aged; Blood Pressure; Conscious Sedation; Coronary Artery Bypass; Coronary Disease; Drug Admi | 1994 |
Prolongation of the QT-interval during induction of anesthesia in patients with coronary artery disease.
Topics: Anesthesia, Intravenous; Blood Pressure; Coronary Disease; Electrocardiography; Etomidate; Female; F | 1994 |
Thoracolumbar epidural blockade as adjunct to high dose fentanyl/midazolam anesthesia in coronary surgery: effects of sternotomy.
Topics: Anesthesia, Epidural; Anesthetics, Intravenous; Catecholamines; Coronary Disease; Drug Therapy, Comb | 1996 |
Comparison of midazolam with or without fentanyl for conscious sedation and hemodynamics in coronary angiography.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anxiety; Conscious Sedation; Coronary Angiograph | 2001 |
Hemodynamic effect of calcium channel blockade during anesthesia for coronary artery surgery.
Topics: Anesthesia, Intravenous; Blood Pressure; Cardiac Output; Cardiopulmonary Bypass; Coronary Artery Byp | 1992 |
Midazolam-ketamine vs sufentanil for rapid sequence induction of anaesthesia for CABG surgery.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Arousal; Coronary | 1990 |
Comparison of the hemodynamic effects of midazolam and diazepam in patients with coronary occlusion.
Topics: Aged; Coronary Artery Bypass; Coronary Disease; Diazepam; Drug Evaluation; Female; Hemodynamics; Hum | 1989 |
[Hemodynamic interaction between midazolam and alfentanil in coronary patients].
Topics: Alfentanil; Anesthetics; Benzodiazepines; Coronary Artery Bypass; Coronary Disease; Drug Interaction | 1986 |
[Low-dose midazolam. Effect on the induction doses of fentanyl and on hemodynamics in the coronary patient].
Topics: Anesthesia, General; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Fentanyl; Hemo | 1988 |
[Comparative hemodynamic study of anesthesia induction with propofol (Diprivan), thiopental, methohexital, etomidate and midazolam in patients with coronary disease].
Topics: Anesthesia, General; Anesthetics; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease | 1987 |
16 other studies available for midazolam and Coronary Disease
| Article | Year |
|---|---|
Hemodynamics in elderly coronary artery disease patients undergoing propofol sedation.
Topics: Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Intraveno | 2006 |
Comparison of sevoflurane and isoflurane in OPCAB surgery.
Topics: Aged; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; | 2007 |
Haemodynamic effects of midazolam in the anaesthetized patient with coronary artery disease.
Topics: Adult; Anesthesia, General; Anti-Anxiety Agents; Benzodiazepines; Blood Pressure; Cardiac Output; Co | 1983 |
Haemodynamic responses to induction of anaesthesia using midazolam in cardiac surgical patients.
Topics: Adult; Aged; Anesthetics; Benzodiazepines; Blood Pressure; Coronary Artery Bypass; Coronary Disease; | 1982 |
Hemodynamic responses to anesthetic induction with midazolam or diazepam in patients with ischemic heart disease.
Topics: Anesthetics; Benzodiazepines; Coronary Disease; Diazepam; Female; Hemodynamics; Humans; Male; Midazo | 1981 |
The effect of midazolam on left ventricular pump performance and contractility in anesthetized patients with coronary artery disease: effect of preoperative ejection fraction.
Topics: Anesthesia; Anesthetics, Intravenous; Coronary Disease; Echocardiography, Transesophageal; Female; H | 1995 |
Midazolam's effects on myocardial load and coronary perfusion: reduced regional O2 consumption and lactate production during ischemia in dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Female; Hea | 1994 |
Myocardial uptake and release of lactate after high dose neurolept endotracheal intubation in coronary surgery.
Topics: Adrenergic beta-Antagonists; Aged; Anesthesia, Inhalation; Coronary Disease; Electrocardiography; Fe | 1993 |
Pacing-induced left ventricular asynchronies in dogs with critical coronary stenosis: mechanisms and effect of anesthetics.
Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cardiac Pacing, Artifici | 1993 |
Anesthesia for laser transmyocardial revascularization.
Topics: Aluminum Silicates; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesth | 1997 |
[The anesthetic management of patients in chronic renal failure for coronary artery bypass surgery without cardiopulmonary bypass].
Topics: Adult; Anesthesia; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Disease; Fentanyl; Human | 1997 |
[Midazolam in heart surgery: applications outside the operating room].
Topics: Cardiac Surgical Procedures; Coronary Disease; Critical Care; Humans; Hypnotics and Sedatives; Midaz | 1998 |
Analgosedation-enhanced baroreflex sensitivity in acute local myocardial ischaemia.
Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Electrocardiography; Fentanyl; Midazolam; Pressorec | 1991 |
Haemodynamic changes during induction of anaesthesia with midazolam and diazepam (Valium) in patients undergoing coronary artery bypass surgery.
Topics: Anesthesia, Intravenous; Benzodiazepines; Coronary Artery Bypass; Coronary Disease; Diazepam; Female | 1985 |
Effects of midazolam on the coronary circulation in patients with coronary artery disease.
Topics: Anesthesia; Angina Pectoris; Benzodiazepines; Blood Gas Analysis; Cardiac Output; Coronary Circulati | 1986 |
Hemodynamic effects of diazepam, flunitrazepam, and midazolam in patients with ischemic heart disease: assessment with a radionuclide approach.
Topics: Adult; Aged; Aged, 80 and over; Coronary Disease; Coronary Vessels; Diazepam; Flunitrazepam; Hemodyn | 1986 |