midazolam has been researched along with Colonic Diseases in 9 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Colonic Diseases: Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate patient satisfaction with propofol compared with nonpropofol (fentanyl/midazolam) anesthesia for outpatient colonoscopies." | 5.24 | Patient Satisfaction With Propofol for Outpatient Colonoscopy: A Prospective, Randomized, Double-Blind Study. ( Frangopoulos, C; Padmanabhan, A; Shaffer, LET, 2017) |
| "Midazolam produced lower SaO(2) values during colonoscopy compared with placebo or control groups (p < 0." | 2.69 | Conscious sedation and cardiorespiratory safety during colonoscopy. ( Hartikainen, J; Heikkinen, M; Janatuinen, E; Julkunen, R; Laitinen, T; Mattila, M; Ristikankare, M; Wang, SX, 2000) |
| " No serious adverse events were seen, and minor sedation-related adverse events occurred with similar frequency in both groups (8." | 1.43 | Capnographic Monitoring of Moderate Sedation During Low-Risk Screening Colonoscopy Does Not Improve Safety or Patient Satisfaction: A Prospective Cohort Study. ( Barnett, S; Bukoye, B; Hung, A; Leffler, DA; Sheehan, J; Sheth, SG; Tsao, R, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Padmanabhan, A | 1 |
| Frangopoulos, C | 1 |
| Shaffer, LET | 1 |
| Lee, JM | 2 |
| Min, G | 1 |
| Keum, B | 1 |
| Kim, SH | 1 |
| Choi, HS | 1 |
| Kim, ES | 1 |
| Seo, YS | 1 |
| Jeen, YT | 1 |
| Chun, HJ | 1 |
| Lee, HS | 1 |
| Um, SH | 1 |
| Kim, CD | 1 |
| Barnett, S | 1 |
| Hung, A | 1 |
| Tsao, R | 1 |
| Sheehan, J | 1 |
| Bukoye, B | 1 |
| Sheth, SG | 1 |
| Leffler, DA | 1 |
| Manolaraki, MM | 1 |
| Theodoropoulou, A | 1 |
| Stroumpos, C | 1 |
| Vardas, E | 1 |
| Oustamanolakis, P | 1 |
| Gritzali, A | 1 |
| Chlouverakis, G | 1 |
| Paspatis, GA | 1 |
| Dafnis, GM | 1 |
| Ristikankare, M | 1 |
| Julkunen, R | 1 |
| Mattila, M | 1 |
| Laitinen, T | 1 |
| Wang, SX | 1 |
| Heikkinen, M | 1 |
| Janatuinen, E | 1 |
| Hartikainen, J | 1 |
| Morrow, JB | 1 |
| Zuccaro, G | 1 |
| Conwell, DL | 1 |
| Vargo, JJ | 1 |
| Dumot, JA | 1 |
| Karafa, M | 1 |
| Shay, SS | 1 |
| Bhardwaj, G | 1 |
| Conlon, S | 1 |
| Bowles, J | 1 |
| Baralt, J | 1 |
| Sipe, BW | 1 |
| Rex, DK | 1 |
| Latinovich, D | 1 |
| Overley, C | 1 |
| Kinser, K | 1 |
| Bratcher, L | 1 |
| Kareken, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Preliminary Characterization of the Capnography Profile of Obstructive Sleep Apnea (OSA) Patients in the Post-Anesthesia Care Unit (PACU)[NCT03076047] | 100 participants (Anticipated) | Observational | 2017-11-06 | Recruiting | |||
| Randomised, Controlled Trial of Intravenous Saline Pre-hydration in Patients Undergoing Outpatient Colonoscopy[NCT00308152] | Phase 2 | 1,000 participants (Anticipated) | Interventional | 2006-02-28 | Completed | ||
| Etomidate With Meperidine vs Midazolam With Meperidine for Sedation During Endodscopic Retrograde Cholangiopancreatogram (ERCP)[NCT02027311] | Phase 4 | 63 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Hypoxia defined as peripheral blood oxygen saturation measured by pulse oxymeter < 90% (NCT02027311)
Timeframe: Every 5min in Preoperative, intraoperative phase and 15 min in Recovery phase
| Intervention | Hypoxia events (Number) |
|---|---|
| Midazolam | 19 |
| Etomidate | 27 |
The frequency of intervention which was defined as any restraint of the patient's head, arms, or legs if they became agitated, or if patient movement was not controlled with verbal instruction from the endoscopist during the whole intraoperative phases. (NCT02027311)
Timeframe: Throughout the whole ERCP procedure
| Intervention | Number of intervention (Mean) |
|---|---|
| Etomidate | 1.9 |
| Midazolam | 7.5 |
7 trials available for midazolam and Colonic Diseases
| Article | Year |
|---|---|
Patient Satisfaction With Propofol for Outpatient Colonoscopy: A Prospective, Randomized, Double-Blind Study.
Topics: Aged; Anesthesia; Anesthetics, Intravenous; Colonic Diseases; Colonoscopy; Double-Blind Method; Fema | 2017 |
Using Etomidate and Midazolam for Screening Colonoscopies Results in More Stable Hemodynamic Responses in Patients of All Ages.
Topics: Adult; Aged; Cardiovascular Diseases; Colonic Diseases; Colonoscopy; Double-Blind Method; Etomidate; | 2019 |
Remifentanil compared with midazolam and pethidine sedation during colonoscopy: a prospective, randomized study.
Topics: Anesthetics, Intravenous; Colonic Diseases; Colonoscopy; Conscious Sedation; Female; Follow-Up Studi | 2008 |
Technical considerations and patient comfort in total colonoscopy with and without a transparent cap: initial experiences from a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia, Intravenous; Anesthetics, Intravenous; Colon | 2000 |
Conscious sedation and cardiorespiratory safety during colonoscopy.
Topics: Adult; Analysis of Variance; Blood Pressure Determination; Cardiovascular Physiological Phenomena; C | 2000 |
Sedation for colonoscopy using a single bolus is safe, effective, and efficient: a prospective, randomized, double-blind trial.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Colonic Diseases; Colonoscopy; Conscious Sedation; Doub | 2000 |
Propofol versus midazolam/meperidine for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Colonic Diseases; Colonoscopy; Drug Therap | 2002 |
Propofol versus midazolam/meperidine for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Colonic Diseases; Colonoscopy; Drug Therap | 2002 |
Propofol versus midazolam/meperidine for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Colonic Diseases; Colonoscopy; Drug Therap | 2002 |
Propofol versus midazolam/meperidine for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Colonic Diseases; Colonoscopy; Drug Therap | 2002 |
2 other studies available for midazolam and Colonic Diseases
| Article | Year |
|---|---|
Capnographic Monitoring of Moderate Sedation During Low-Risk Screening Colonoscopy Does Not Improve Safety or Patient Satisfaction: A Prospective Cohort Study.
Topics: Adult; Aged; Aged, 80 and over; Capnography; Cohort Studies; Colonic Diseases; Colonoscopy; Consciou | 2016 |
Use of midazolam and propofol during colonoscopy: 7 years of experience.
Topics: Adult; Aged; Aged, 80 and over; Colonic Diseases; Colonoscopy; Conscious Sedation; Dose-Response Rel | 2002 |