midazolam has been researched along with Cognitive Decline in 3 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We recently reported a role for the circadian rhythm protein Period 2 (PER2) in midazolam induced cognitive dysfunction." | 7.96 | A Role for the Adenosine ADORA2B Receptor in Midazolam Induced Cognitive Dysfunction. ( Eckle, T; Gile, J; Oyama, Y; Shuff, S, 2020) |
| "We recently reported a role for the circadian rhythm protein Period 2 (PER2) in midazolam induced cognitive dysfunction." | 3.96 | A Role for the Adenosine ADORA2B Receptor in Midazolam Induced Cognitive Dysfunction. ( Eckle, T; Gile, J; Oyama, Y; Shuff, S, 2020) |
| " The purpose of this study was to identify the factors and procedure time associated with the use of intravenous sedation with propofol alone or propofol combined with midazolam in dental patients with special needs." | 1.62 | A comparative study of propofol alone and propofol combined with midazolam for dental treatments in special needs patients. ( Chen, SL; Chong, SY; Huang, MS; Huang, TS; Lin, IH; Tsai, HH; Wang, PY, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Gile, J | 1 |
| Oyama, Y | 1 |
| Shuff, S | 1 |
| Eckle, T | 1 |
| Lin, IH | 1 |
| Huang, MS | 1 |
| Wang, PY | 1 |
| Huang, TS | 1 |
| Chong, SY | 1 |
| Chen, SL | 1 |
| Tsai, HH | 1 |
| Li, WX | 1 |
| Luo, RY | 1 |
| Chen, C | 1 |
| Li, X | 1 |
| Ao, JS | 1 |
| Liu, Y | 1 |
| Yin, YQ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketofol vs Dexmedetomidine for Preventing Post-operative Delirium in Elderly Patients Undergoing Intestinal Obstruction Surgeries. A Randomized Controlled Study[NCT04816162] | Phase 4 | 120 participants (Actual) | Interventional | 2021-03-25 | Completed | ||
| The Effects of Different Anesthesia Methods on Perioperative Neurocognitive Disorders in the Elderly: a Randomized Controlled Trial[NCT04488952] | 350 participants (Anticipated) | Interventional | 2020-07-08 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for midazolam and Cognitive Decline
| Article | Year |
|---|---|
Effects of propofol, dexmedetomidine, and midazolam on postoperative cognitive dysfunction in elderly patients: a randomized controlled preliminary trial.
Topics: Aged; Cognitive Dysfunction; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazol | 2019 |
Effects of propofol, dexmedetomidine, and midazolam on postoperative cognitive dysfunction in elderly patients: a randomized controlled preliminary trial.
Topics: Aged; Cognitive Dysfunction; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazol | 2019 |
Effects of propofol, dexmedetomidine, and midazolam on postoperative cognitive dysfunction in elderly patients: a randomized controlled preliminary trial.
Topics: Aged; Cognitive Dysfunction; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazol | 2019 |
Effects of propofol, dexmedetomidine, and midazolam on postoperative cognitive dysfunction in elderly patients: a randomized controlled preliminary trial.
Topics: Aged; Cognitive Dysfunction; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazol | 2019 |
2 other studies available for midazolam and Cognitive Decline
| Article | Year |
|---|---|
A Role for the Adenosine ADORA2B Receptor in Midazolam Induced Cognitive Dysfunction.
Topics: Adenosine; Animals; Cognitive Dysfunction; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Midazolam; | 2020 |
A comparative study of propofol alone and propofol combined with midazolam for dental treatments in special needs patients.
Topics: Adjuvants, Anesthesia; Administration, Intravenous; Adolescent; Adult; Affective Symptoms; Child; Co | 2021 |