midazolam has been researched along with Clostridium tetani Infection in 8 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is a case of a 31-year-old Filipino man with chronic methamphetamine use disorder who developed tetanus from a necrotic skin graft over his left calcaneus, which was fractured after a motor vehicular accident." | 7.88 | Rocuronium for control of muscle spasms in a tetanus patient with chronic methamphetamine use disorder. ( Abejero, JEE; Enriquez, CAG; Maligaso, CPD; Ramiro, PA, 2018) |
| " Midazolam was administered as an antispastic therapy followed by human tetanus immune globulin and tetanus toxoid." | 7.73 | [Antispasm therapy using combination of midazolam and propofol for severe tetanus]. ( Hirano, T; Kamikawa, M; Kinoshita, Y; Uchino, M; Watanabe, M; Yonemitsu, K, 2005) |
| "A case of severe tetanus with autonomic dysfunction is reported, describing the adequate response to continuous infusions of both propofol and midazolam, and the successful use of clonidine to control sympathetic over-activity." | 7.68 | [Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus]. ( Peduto, VA; Piga, M; Pisanu, GM, 1993) |
| "Midazolam was used for prolonged sedation in ten adult patients with severe tetanus in the Intensive Care Unit for periods ranging from 10 to 50 days." | 7.68 | Midazolam for prolonged intravenous sedation in patients with tetanus. ( Fahr, J; Gyasi, HK; Kurian, E; Mathew, M, 1993) |
| "An adult patient with severe tetanus was successfully treated with alternating long-term infusions of propofol (20-80 mg/h, 8 + 3 days) and midazolam (5-15 mg/h, 29 days) for sedation, and with vecuronium infusion (6-8 mg/h, 35 days) for muscle relaxation." | 7.67 | Intravenous infusion of midazolam, propofol and vecuronium in a patient with severe tetanus. ( Himberg, JJ; Orko, R; Rosenberg, PH, 1988) |
| "This is a case of a 31-year-old Filipino man with chronic methamphetamine use disorder who developed tetanus from a necrotic skin graft over his left calcaneus, which was fractured after a motor vehicular accident." | 3.88 | Rocuronium for control of muscle spasms in a tetanus patient with chronic methamphetamine use disorder. ( Abejero, JEE; Enriquez, CAG; Maligaso, CPD; Ramiro, PA, 2018) |
| " Midazolam was administered as an antispastic therapy followed by human tetanus immune globulin and tetanus toxoid." | 3.73 | [Antispasm therapy using combination of midazolam and propofol for severe tetanus]. ( Hirano, T; Kamikawa, M; Kinoshita, Y; Uchino, M; Watanabe, M; Yonemitsu, K, 2005) |
| "The assessment of modifications in the tetanus treatment, which included using metronidazol and midazolam instead penicillin and diazepam, was presented." | 3.70 | [Modifications in treatment of tetanus and prognosis--observations from the Cracow Department of Infectious Diseases]. ( Bociaga-Jasik, M; Caban, J; Garlicki, A; Kluba-Wojewoda, U; Krukowiecki, J, 1999) |
| "A case of severe tetanus with autonomic dysfunction is reported, describing the adequate response to continuous infusions of both propofol and midazolam, and the successful use of clonidine to control sympathetic over-activity." | 3.68 | [Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus]. ( Peduto, VA; Piga, M; Pisanu, GM, 1993) |
| "Midazolam was used for prolonged sedation in ten adult patients with severe tetanus in the Intensive Care Unit for periods ranging from 10 to 50 days." | 3.68 | Midazolam for prolonged intravenous sedation in patients with tetanus. ( Fahr, J; Gyasi, HK; Kurian, E; Mathew, M, 1993) |
| "An adult patient with severe tetanus was successfully treated with alternating long-term infusions of propofol (20-80 mg/h, 8 + 3 days) and midazolam (5-15 mg/h, 29 days) for sedation, and with vecuronium infusion (6-8 mg/h, 35 days) for muscle relaxation." | 3.67 | Intravenous infusion of midazolam, propofol and vecuronium in a patient with severe tetanus. ( Himberg, JJ; Orko, R; Rosenberg, PH, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Enriquez, CAG | 1 |
| Abejero, JEE | 1 |
| Ramiro, PA | 1 |
| Maligaso, CPD | 1 |
| Araki, T | 1 |
| Iwanami, N | 1 |
| Yamazaki, Y | 1 |
| Kamikawa, M | 1 |
| Watanabe, M | 1 |
| Hirano, T | 1 |
| Yonemitsu, K | 1 |
| Kinoshita, Y | 1 |
| Uchino, M | 1 |
| Thwaites, CL | 1 |
| Yen, LM | 1 |
| Loan, HT | 1 |
| Thuy, TT | 1 |
| Thwaites, GE | 1 |
| Stepniewska, K | 1 |
| Soni, N | 1 |
| White, NJ | 1 |
| Farrar, JJ | 1 |
| Peduto, VA | 1 |
| Pisanu, GM | 1 |
| Piga, M | 1 |
| Gyasi, HK | 1 |
| Fahr, J | 1 |
| Kurian, E | 1 |
| Mathew, M | 1 |
| Garlicki, A | 1 |
| Caban, J | 1 |
| Bociaga-Jasik, M | 1 |
| Kluba-Wojewoda, U | 1 |
| Krukowiecki, J | 1 |
| Orko, R | 1 |
| Rosenberg, PH | 1 |
| Himberg, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intrathecal Immunoglobulin for Treatment of Adult Patients With Tetanus: a Randomized Controlled 2x2 Factorial Trial[NCT02999815] | Phase 1/Phase 2 | 272 participants (Actual) | Interventional | 2017-02-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for midazolam and Clostridium tetani Infection
| Article | Year |
|---|---|
Magnesium sulphate for treatment of severe tetanus: a randomised controlled trial.
Topics: Adult; Aged; Anticonvulsants; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infusion | 2006 |
7 other studies available for midazolam and Clostridium tetani Infection
| Article | Year |
|---|---|
Rocuronium for control of muscle spasms in a tetanus patient with chronic methamphetamine use disorder.
Topics: Adult; Amphetamine-Related Disorders; Androstanols; Anesthetics, Intravenous; Humans; Infusions, Int | 2018 |
Severe Tetanus Complicated by Takotsubo Cardiomyopathy.
Topics: Aged; Anti-Bacterial Agents; Arrhythmias, Cardiac; Diazepam; Echocardiography; Electrocardiography; | 2019 |
[Antispasm therapy using combination of midazolam and propofol for severe tetanus].
Topics: Aged; Drug Therapy, Combination; Female; Humans; Midazolam; Parasympatholytics; Propofol; Tetanus | 2005 |
[Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus].
Topics: Aged; Autonomic Nervous System; Clonidine; Conscious Sedation; Female; Humans; Midazolam; Propofol; | 1993 |
Midazolam for prolonged intravenous sedation in patients with tetanus.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Infusions, Intravenous; Male; Midazolam; Middle Aged | 1993 |
[Modifications in treatment of tetanus and prognosis--observations from the Cracow Department of Infectious Diseases].
Topics: Aged; Aged, 80 and over; Diazepam; Drug Therapy, Combination; Female; Humans; Length of Stay; Male; | 1999 |
Intravenous infusion of midazolam, propofol and vecuronium in a patient with severe tetanus.
Topics: Aged; Drug Administration Schedule; Humans; Infusions, Intravenous; Male; Midazolam; Phenols; Propof | 1988 |