Page last updated: 2024-10-31

midazolam and Cirrhosis

midazolam has been researched along with Cirrhosis in 3 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
"We evaluated the efficacy and gastroenterologist/patient satisfaction of midazolam combined with oxycodone, relative to that of midazolam combined with sufentanil, for anesthesia during endoscopic injection sclerotherapy (EIS) in patients with cirrhosis and esophageal varices."9.27Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices. ( Chi, P; He, H; Luo, C; Quan, Z; Wang, L, 2018)
"We evaluated the efficacy and gastroenterologist/patient satisfaction of midazolam combined with oxycodone, relative to that of midazolam combined with sufentanil, for anesthesia during endoscopic injection sclerotherapy (EIS) in patients with cirrhosis and esophageal varices."5.27Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices. ( Chi, P; He, H; Luo, C; Quan, Z; Wang, L, 2018)
"Midazolam was associated with the deterioration of psychometric scores for a longer period than propofol."2.52Propofol versus midazolam for upper gastrointestinal endoscopy in cirrhotic patients: a meta-analysis of randomized controlled trials. ( Chen, CY; Chen, TL; Ko, CL; Lin, YC; Lou, HY; Tam, KW; Tsai, HC, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Quan, Z1
Luo, C1
Chi, P1
Wang, L1
He, H1
Tsai, HC1
Lin, YC1
Ko, CL1
Lou, HY1
Chen, TL1
Tam, KW1
Chen, CY1
Steinlauf, AF1
Garcia-Tsao, G1
Zakko, MF1
Dickey, K1
Gupta, T1
Groszmann, RJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Fentanyl Analgesia on the Accuracy of Hepatic Venous Pressure Gradient Measurements in Patients With Portal Hypertension:a Prospective, Multicenter Study[NCT04724148]4 participants (Anticipated)Interventional2022-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for midazolam and Cirrhosis

ArticleYear
Propofol versus midazolam for upper gastrointestinal endoscopy in cirrhotic patients: a meta-analysis of randomized controlled trials.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Anesthesia Recovery Period; Bradycardia; Deep Sedation; Endoscopy, Gastrointestinal; Fibrosis; Hepat

2015

Trials

2 trials available for midazolam and Cirrhosis

ArticleYear
Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia; Body Mass Index; Double-Blind Method; Drug Therapy, Com

2018
Low-dose midazolam sedation: an option for patients undergoing serial hepatic venous pressure measurements.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:4

    Topics: Anti-Anxiety Agents; Anxiety; Catheterization; Dose-Response Relationship, Drug; Double-Blind Method

1999