midazolam has been researched along with Chronic Hepatitis B in 1 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ritonavir is a powerful inhibitor of cytochrome P450 3A (CYP3A) that metabolizes many antiretrovirals." | 2.73 | Ritonavir greatly impairs CYP3A activity in HIV infection with chronic viral hepatitis. ( Greenblatt, DJ; Kaufman, RC; Knox, TA; Oleson, L; von Moltke, LL; Wanke, CA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Knox, TA | 1 |
| Oleson, L | 1 |
| von Moltke, LL | 1 |
| Kaufman, RC | 1 |
| Wanke, CA | 1 |
| Greenblatt, DJ | 1 |
1 trial available for midazolam and Chronic Hepatitis B
| Article | Year |
|---|---|
Ritonavir greatly impairs CYP3A activity in HIV infection with chronic viral hepatitis.
Topics: Administration, Oral; Adult; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome | 2008 |