Page last updated: 2024-10-31

midazolam and Canine Diseases

midazolam has been researched along with Canine Diseases in 11 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
"To determine the dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in American Society of Anesthesiologists status ≥III dogs requiring emergency abdominal surgery."9.34Dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in critically ill dogs. ( Aguilera, R; Bateman, S; Hanna, B; Sinclair, M; Valverde, A, 2020)
"To evaluate the clinical efficacy of intranasal midazolam (IN-MDZ), via a mucosal atomization device, as a first-line management option for canine status epilepticus and compare it to rectal administration of diazepam (R-DZP) for controlling status epilepticus before intravenous access is available."9.24Intranasal Midazolam versus Rectal Diazepam for the Management of Canine Status Epilepticus: A Multicenter Randomized Parallel-Group Clinical Trial. ( Bhatti, SFM; Charalambous, M; Gallucci, A; Gandini, G; Hasegawa, D; Ives, E; Jeffery, ND; Musteata, M; Platt, S; Siedenburg, J; Tipold, A; Van Ham, L; Vanhaesebrouck, AE; Volk, HA, 2017)
"Midazolam delivered by continuous rate infusion (CRI) might be effective in dogs with cluster seizures (CS) or status epilepticus (SE)."8.02Continuous rate infusion of midazolam as emergent treatment for seizures in dogs. ( Bray, KY; Early, PJ; Mariani, CL; Muñana, KR; Olby, NJ, 2021)
"To compare IN versus IV midazolam (MDZ) at the same dosage (0."6.90Comparison of intranasal versus intravenous midazolam for management of status epilepticus in dogs: A multi-center randomized parallel group clinical study. ( Bhatti, SFM; Broeckx, BJG; Cappello, R; Charalambous, M; Coates, JR; Corlazzoli, D; Cozzi, F; De Risio, L; Erath, J; Gallucci, A; Gandini, G; Hasegawa, D; Huenerfauth, E; Musteata, M; Pancotto, T; Platt, S; Porcarelli, L; Rossmeisl, JH; Tipold, A; Tirrito, F; Van Ham, L; Vanhaesebrouck, A; Volk, HA, 2019)
"To determine the dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in American Society of Anesthesiologists status ≥III dogs requiring emergency abdominal surgery."5.34Dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in critically ill dogs. ( Aguilera, R; Bateman, S; Hanna, B; Sinclair, M; Valverde, A, 2020)
"To evaluate the clinical efficacy of intranasal midazolam (IN-MDZ), via a mucosal atomization device, as a first-line management option for canine status epilepticus and compare it to rectal administration of diazepam (R-DZP) for controlling status epilepticus before intravenous access is available."5.24Intranasal Midazolam versus Rectal Diazepam for the Management of Canine Status Epilepticus: A Multicenter Randomized Parallel-Group Clinical Trial. ( Bhatti, SFM; Charalambous, M; Gallucci, A; Gandini, G; Hasegawa, D; Ives, E; Jeffery, ND; Musteata, M; Platt, S; Siedenburg, J; Tipold, A; Van Ham, L; Vanhaesebrouck, AE; Volk, HA, 2017)
"Midazolam delivered by continuous rate infusion (CRI) might be effective in dogs with cluster seizures (CS) or status epilepticus (SE)."4.02Continuous rate infusion of midazolam as emergent treatment for seizures in dogs. ( Bray, KY; Early, PJ; Mariani, CL; Muñana, KR; Olby, NJ, 2021)
" The aim of this report is to describe a suspected anaphylactic reaction to propofol in a 14 years old Shih-Tzu undergoing general anaesthesia for ovariohysterectomy due to a pyometra."4.02A Suspected Anaphylactoid Reaction to Propofol in a Dog. ( Del Prete, T; Scarabelli, S, 2021)
"To determine the frequency, severity and duration of adverse events including myoclonus, pain on injection, hypersalivation, regurgitation and apnoea after administration of midazolam or saline followed by etomidate in hydromorphone premedicated dogs."3.01Descriptive assessment of adverse events associated with midazolam-etomidate versus saline-etomidate in healthy hydromorphone premedicated dogs. ( Calbay, R; da Cunha, AF; Hofmeister, EH; Jones, TL, 2021)
"To compare IN versus IV midazolam (MDZ) at the same dosage (0."2.90Comparison of intranasal versus intravenous midazolam for management of status epilepticus in dogs: A multi-center randomized parallel group clinical study. ( Bhatti, SFM; Broeckx, BJG; Cappello, R; Charalambous, M; Coates, JR; Corlazzoli, D; Cozzi, F; De Risio, L; Erath, J; Gallucci, A; Gandini, G; Hasegawa, D; Huenerfauth, E; Musteata, M; Pancotto, T; Platt, S; Porcarelli, L; Rossmeisl, JH; Tipold, A; Tirrito, F; Van Ham, L; Vanhaesebrouck, A; Volk, HA, 2019)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's4 (36.36)24.3611
2020's4 (36.36)2.80

Authors

AuthorsStudies
Charalambous, M2
Volk, HA2
Tipold, A2
Erath, J1
Huenerfauth, E1
Gallucci, A2
Gandini, G2
Hasegawa, D2
Pancotto, T1
Rossmeisl, JH1
Platt, S2
De Risio, L1
Coates, JR1
Musteata, M2
Tirrito, F1
Cozzi, F1
Porcarelli, L1
Corlazzoli, D1
Cappello, R1
Vanhaesebrouck, A1
Broeckx, BJG1
Van Ham, L2
Bhatti, SFM2
Aguilera, R1
Sinclair, M1
Valverde, A1
Bateman, S1
Hanna, B1
Bray, KY1
Mariani, CL1
Early, PJ1
Muñana, KR1
Olby, NJ1
Jones, TL1
Calbay, R1
da Cunha, AF1
Hofmeister, EH1
Del Prete, T1
Scarabelli, S1
Jeffery, ND1
Siedenburg, J1
Ives, E1
Vanhaesebrouck, AE1
Jang, M1
Shin, CW1
Choi, S1
Won, S1
Lee, I1
Adami, C1
Spadavecchia, C1
Casoni, D1
Estrada, AH1
Ko, JC1
Snyder, PS1
Sobel, KE1
Smith, LJ1
Stepien, RL1
Willis, CK1
Quinn, RP1
McDonell, WM1
Gati, J1
Parent, J1
Nicolle, D1

Trials

4 trials available for midazolam and Canine Diseases

ArticleYear
Comparison of intranasal versus intravenous midazolam for management of status epilepticus in dogs: A multi-center randomized parallel group clinical study.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:6

    Topics: Administration, Intranasal; Animals; Dog Diseases; Dogs; Female; Injections, Intravenous; Male; Mida

2019
Dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in critically ill dogs.
    Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:4

    Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Critical Illness; Dog Diseases

2020
Descriptive assessment of adverse events associated with midazolam-etomidate versus saline-etomidate in healthy hydromorphone premedicated dogs.
    The Journal of small animal practice, 2021, Volume: 62, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Dog Diseases; Dogs; Etomidate; Hydromorphone; Midazolam; Myoclonu

2021
Intranasal Midazolam versus Rectal Diazepam for the Management of Canine Status Epilepticus: A Multicenter Randomized Parallel-Group Clinical Trial.
    Journal of veterinary internal medicine, 2017, Volume: 31, Issue:4

    Topics: Administration, Intranasal; Administration, Rectal; Animals; Anticonvulsants; Diazepam; Dog Diseases

2017

Other Studies

7 other studies available for midazolam and Canine Diseases

ArticleYear
Continuous rate infusion of midazolam as emergent treatment for seizures in dogs.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:1

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Hospitals, Animal; Hospitals, Teaching; Midazolam; Ret

2021
A Suspected Anaphylactoid Reaction to Propofol in a Dog.
    Topics in companion animal medicine, 2021, Volume: 44

    Topics: Anaphylaxis; Anesthetics, Intravenous; Animals; Dog Diseases; Dogs; Female; Hysterectomy; Midazolam;

2021
Anesthesia Case of the Month.
    Journal of the American Veterinary Medical Association, 2018, Aug-01, Volume: 253, Issue:3

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Arnold-Chiari Malformation; Diagnosis, Differential;

2018
Seizure activity occurring in two dogs after S-ketamine-induction.
    Schweizer Archiv fur Tierheilkunde, 2013, Volume: 155, Issue:10

    Topics: Acepromazine; Analgesics, Opioid; Anesthesia, General; Anesthetics, Dissociative; Animals; Anticonvu

2013
Anesthesia case of the month. Pacemaker malfunction during anesthesia in a dog.
    Journal of the American Veterinary Medical Association, 1998, Oct-01, Volume: 213, Issue:7

    Topics: Analgesics, Opioid; Animals; Butorphanol; Cardiac Pacing, Artificial; Dog Diseases; Dogs; Electrocar

1998
Anesthesia case of the month. Anesthesia in a dog with tricuspid insufficiency and atrial fibrillation.
    Journal of the American Veterinary Medical Association, 1999, Feb-01, Volume: 214, Issue:3

    Topics: Analgesics, Opioid; Anesthesia; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local;

1999
Functional MRI as a tool to assess vision in dogs: the optimal anesthetic.
    Veterinary ophthalmology, 2001, Volume: 4, Issue:4

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dog Diseases; Dogs; Eye Dise

2001