Page last updated: 2024-10-31

midazolam and Cancer of Stomach

midazolam has been researched along with Cancer of Stomach in 11 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
"Patients scheduled to undergo ESD for early gastric cancer or adenoma were randomly assigned to sedation with midazolam or propofol, and consciousness level was evaluated by bispectral index (BIS) monitoring."5.16Propofol sedation with bispectral index monitoring is useful for endoscopic submucosal dissection: a randomized prospective phase II clinical trial. ( Azuma, M; Higuchi, K; Ishido, K; Katada, C; Koizumi, W; Naruke, A; Sasaki, T; Sato, A; Tanabe, S, 2012)
"Although the treatment of early gastric cancer with endoscopic submucosal dissection (ESD) has been widely carried out, a standardized method of sedation for ESD has not been established."2.76Sedation with dexmedetomidine hydrochloride during endoscopic submucosal dissection of gastric cancer. ( Fujinaga, Y; Kashiwa, A; Kojima, Y; Matsuyama, K; Shimamoto, F; Takimoto, K; Toyonaga, T; Ueda, T; Yamauchi, H; Yoshikawa, T, 2011)
"Propofol has a very short half-life and can be administered continuously, which is advantageous for long-term sedation."2.76Efficacy of propofol sedation for endoscopic submucosal dissection (ESD): assessment with prospective data collection. ( Fujita, N; Harada, Y; Hirasawa, D; Koike, Y; Maeda, Y; Noda, Y; Obana, T; Ohira, T; Sugawara, T; Suzuki, K; Suzuki, T; Yamagata, T, 2011)
"Propofol-treated patients had a quicker recovery profile than those treated with MDZ."2.75Safe and effective sedation in endoscopic submucosal dissection for early gastric cancer: a randomized comparison between propofol continuous infusion and intermittent midazolam injection. ( Gotoda, T; Hirashima, T; Kiriyama, S; Kusano, C; Kuwano, H; Nishimoto, F; Oda, I; Sano, H, 2010)
"Therapeutic endoscopy of early gastric cancers can often be performed with only moderate sedation."2.50Propofol sedation during endoscopic treatment for early gastric cancer compared to midazolam. ( Kiriyama, S; Kuwano, H; Naitoh, H, 2014)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's10 (90.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sasaki, T2
Tanabe, S2
Ishido, K2
Azuma, M2
Katada, C2
Higuchi, K2
Koizumi, W2
Yamamoto, H1
Gotoda, T2
Nakamura, T1
Yamamoto, T1
Kikuchi, H1
Kitamura, M1
Itoi, T1
Moriyasu, F1
Kiriyama, S2
Naitoh, H1
Kuwano, H2
Lee, SP1
Sung, IK1
Kim, JH1
Lee, SY1
Park, HS1
Shim, CS1
Hwang, HK1
Kim, TY1
Shim, SG1
Shin, S1
Park, CH1
Kim, HJ1
Park, SH1
Lee, SK1
Yoo, YC1
Sano, H1
Oda, I1
Nishimoto, F1
Hirashima, T1
Kusano, C1
Takimoto, K1
Ueda, T1
Shimamoto, F1
Kojima, Y1
Fujinaga, Y1
Kashiwa, A1
Yamauchi, H1
Matsuyama, K1
Toyonaga, T1
Yoshikawa, T1
Yamagata, T1
Hirasawa, D1
Fujita, N1
Suzuki, T1
Obana, T1
Sugawara, T1
Ohira, T1
Harada, Y1
Maeda, Y1
Koike, Y1
Suzuki, K1
Noda, Y1
Sato, A1
Naruke, A1
Rong, QH1
Zhao, GL1
Xie, JP1
Wang, LX1
Honda, A1
Arai, T1
Akiyama, M1
Masuda, E1
Kobayashi, M1
Hoka, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial[NCT03453359]180 participants (Actual)Interventional2018-01-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for midazolam and Cancer of Stomach

ArticleYear
Recommended sedation and intraprocedural monitoring for gastric endoscopic submucosal dissection.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2013, Volume: 25 Suppl 1

    Topics: Analgesics, Opioid; Benzodiazepines; Conscious Sedation; Dissection; Gastric Mucosa; Guideline Adher

2013
Propofol sedation during endoscopic treatment for early gastric cancer compared to midazolam.
    World journal of gastroenterology, 2014, Sep-14, Volume: 20, Issue:34

    Topics: Body Weight; Conscious Sedation; Dissection; Drug Dosage Calculations; Gastroscopy; Humans; Hypnotic

2014

Trials

8 trials available for midazolam and Cancer of Stomach

ArticleYear
Clinical impact of gastroenterologist-administered propofol during esophagogastroduodenoscopy: a randomized comparison at a single medical clinic.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2015, Volume: 18, Issue:2

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Endoscopy, Digestive System; Fema

2015
Comparison of dexmedetomidine with on-demand midazolam versus midazolam alone for procedural sedation during endoscopic submucosal dissection of gastric tumor.
    Journal of digestive diseases, 2015, Volume: 16, Issue:7

    Topics: Aged; Aged, 80 and over; Conscious Sedation; Dexmedetomidine; Dissection; Double-Blind Method; Drug

2015
Patient satisfaction after endoscopic submucosal dissection under propofol-based sedation: a small premedication makes all the difference.
    Surgical endoscopy, 2017, Volume: 31, Issue:6

    Topics: Adenoma; Aged; Anesthetics, Intravenous; Carcinoma; Conscious Sedation; Endoscopic Mucosal Resection

2017
Safe and effective sedation in endoscopic submucosal dissection for early gastric cancer: a randomized comparison between propofol continuous infusion and intermittent midazolam injection.
    Journal of gastroenterology, 2010, Volume: 45, Issue:8

    Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthetics, Intravenous; Conscious Sedation; D

2010
Sedation with dexmedetomidine hydrochloride during endoscopic submucosal dissection of gastric cancer.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2011, Volume: 23, Issue:2

    Topics: Adenocarcinoma; Adenoma; Aged; Aged, 80 and over; Arousal; Conscious Sedation; Dexmedetomidine; Diss

2011
Efficacy of propofol sedation for endoscopic submucosal dissection (ESD): assessment with prospective data collection.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:14

    Topics: Aged; Anesthetics, Intravenous; Cardiovascular System; Depression, Chemical; Dissection; Endoscopy,

2011
Propofol sedation with bispectral index monitoring is useful for endoscopic submucosal dissection: a randomized prospective phase II clinical trial.
    Endoscopy, 2012, Volume: 44, Issue:6

    Topics: Adenoma; Aged; Aged, 80 and over; Anesthetics, Intravenous; Bradycardia; Chi-Square Distribution; Co

2012
Feasibility and safety of endoscopic submucosal dissection of esophageal or gastric carcinomas under general anesthesia.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2013, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Diazepam; Endoscopy, Gastrointestinal; Esophage

2013

Other Studies

1 other study available for midazolam and Cancer of Stomach

ArticleYear
Anesthetic management of a patient with a history of Batista procedure for dilated cardiomyopathy undergoing gastric surgery.
    Journal of anesthesia, 2006, Volume: 20, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine

2006